Image 10_Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.tif حسب Wuyuan Liao (21776432)

"…</p>Methods<p>We systematically collected and analyzed genomic and clinical data from patients receiving anti-PD-1/PD-L1 immunotherapy across multiple cohorts. …"

Image 1_Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.tif حسب Wuyuan Liao (21776432)

"…</p>Methods<p>We systematically collected and analyzed genomic and clinical data from patients receiving anti-PD-1/PD-L1 immunotherapy across multiple cohorts. …"

Image 3_Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.tif حسب Wuyuan Liao (21776432)

"…</p>Methods<p>We systematically collected and analyzed genomic and clinical data from patients receiving anti-PD-1/PD-L1 immunotherapy across multiple cohorts. …"

Image 5_Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.tif حسب Wuyuan Liao (21776432)

"…</p>Methods<p>We systematically collected and analyzed genomic and clinical data from patients receiving anti-PD-1/PD-L1 immunotherapy across multiple cohorts. …"

Image 8_Interplay between tumor mutation burden and the tumor microenvironment predicts the prognosis of pan-cancer anti-PD-1/PD-L1 therapy.tif حسب Wuyuan Liao (21776432)

"…</p>Methods<p>We systematically collected and analyzed genomic and clinical data from patients receiving anti-PD-1/PD-L1 immunotherapy across multiple cohorts. …"

Supplementary file 1_Gene expression profile in colon cancer therapeutic resistance and its relationship with the tumor microenvironment.docx حسب Priscila Galvão Doria (22518647)

"…The following algorithms were used: i. Limma was applied to identify differentially expressed genes; ii. …"

<b>dGenhancer v2</b>: A software tool for designing oligonucleotides that can trigger gene-specific Enhancement of Protein Translation. حسب Adam Master (20316450)

"…Prediction of total Gibbs energies (ΔG=ΔH–TΔS) of the 5’UTR structures can be performed using RNAstructure version 5.2. ΔGs are input data for final dGenhancer calculations as shown by Master A et al 2016¹</p><p dir="ltr"> The algorithms of the calculator were constructed to visualize ΔG changes after <i>in silico</i> introduced single nucleotide substitutions (SNPs) of the 5’UTR sequences. …"