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Resveratrol-Elicited PKC Inhibition Counteracts NOX-Mediated Endothelial to Mesenchymal Transition in Human Retinal Endothelial Cells Exposed to High Glucose
Published 2021“…<p dir="ltr">Diabetes-associated long-term hyperglycaemia leads to oxidative stress-mediated fibrosis in different tissues and organs. …”
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Human Recombinant Arginase I (Co)-PEG5000-Induced Arginine Depletion of Breast Cancer Cell Lines Causes Autophagy Mediated Cell Death
Published 2024“…In this study, we showed for the first time that arginine deprivation induced by a recombinant human arginase drug induces selective cytotoxicity mediated by autophagy in distinct human breast cancer cell lines. …”
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masterThesis -
25
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…Addition of N-acetyl-cysteine (NAC); being a reactive oxygen species (ROS) scavenger, led to a significant decrease in the cytotoxicity of arginine deprivation to U251 and A172 cells, indicating that ROS generation reversed the cytotoxicity of arginine deprivation to GBM cells. …”
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masterThesis -
26
Preparation of albumin-targeted liposomes and the study of their release characteristics using ultrasound
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doctoralThesis -
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1787 evaluation of transperineal prostatic administration of a PSA-activasted protoxin (PRX302) in men with luts secondary to BPH
Published 2010“…In the Phase I study, mean IPSS showed a decrease of 6.5 points (34%), mean QoL a decrease of 2 points (44%) and mean prostate volume a decrease of 5.5 cc (13%) at 12-months compared to screening. …”
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Cryomyolysis, a new procedure for the conservative treatment of uterine fibroids
Published 1998“…Normal uterine volume ranged from 35.6 to 548.7 ml preoperatively and 45.1 to 729.6 ml postoperatively (mean increase 40%); however, myoma volume showed a mean decrease of 6% (range-87-28%). …”
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Exercise-induced Citrate Enhances Associative Memory Formation by Modulating Histone Acetylation in a Sex-dependent manner
Published 2023“…The benefits of exercise on cognition are mediated by an increase in brain-derived neurotrophic factor (BDNF) levels in the hippocampus. …”
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masterThesis -
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
Published 2021“…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …”
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Sequential therapy in patients receiving Fluoroquinolones at the American University of Beirut Medical Center. (c2001)
Published 2001“…Date of switch (if applicable), oral antibiotic chosen, mean time to switch, mean hospital duration, and mean treatment duration were also recorded. …”
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masterThesis -
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Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
Published 2019“…[HuArgI (Co)-PEG5000]-induced arginine deprivation led to extensive and prolonged activation of autophagy, which proved to be deleterious to cell survival since its inhibition led to a significant decrease in cytotoxicity. This indicates that the activation of autophagy following arginine-deprivation, rather than being protective, mediates cell cytotoxicity leading to death by autophagy.…”
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
Published 2023“…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …”
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Rescue cerclage
Published 2006“…Advanced dilation of 3 cm and/or prolapsed membranes (n = 18) did not decrease the likelihood of reaching 28 weeks. Mean gestational age at delivery for this subset of patients was 30.7 ± 7.2 weeks. …”
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Role of intravitreal antivascular endothelial growth factor injections for choroidal neovascularization due to choroidal osteoma
Published 2014“…By paired comparison, mean decrease from baseline was 119.7 microns at 6 months (n = 15; P = 0.001 ), 105.3 microns at 1 year (n = 10; P = 0.03 ), and 157.6 microns at 2 years (n = 7;p = 0.08 ). …”
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The Impact of Perceived Economic Threat on Turnover Intentions in Lebanese Universities
Published 2023“…Furthermore, emotional exhaustion fully mediates the relationship between perceived economic threat and faculty turnover intention. …”
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masterThesis -
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Wait! What’s my job? Role ambiguity and role conflict as predictors of commitment among faculty
Published 2024“…Structural equation modeling indicates that job satisfaction partially mediates the relationship between role ambiguity and affective commitment, while not mediating the relationship between role ambiguity and normative and continuance commitments. …”
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Raising awareness among health educators and educational institutions of the need to overcome the language barrier among Non-Native English speaking students of Health Sciences in...
Published 2015“…This study showed a decrease in 2014 for the proportion of students in the foundation year that studied sciences in English with 73% in 2013 to 39% in 2014. …”
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