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241
Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch
منشور في 2025"…BackgroundAtopic dermatitis (AD) is a multifaceted inflammatory skin disease characterized by chronic itch and acute itch flare (AIF), with basophils playing pivotal roles in both. VAMP7 mediates immune responses; however, its function in basophils remains undefined. …"
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article -
242
A component analysis of positive behaviour support plans
منشور في 2012"…This paper investigates which components are most effective and which factors might mediate effectiveness. Method Sixty-one staff working with individuals with intellectual disability and challenging behaviours completed longitudinal competency-based training in PBS. …"
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article -
243
Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema
منشور في 2010"…Administration of sphingosine decreased the ceramide-to-S1P ratio in the lung and inhibited alveolar space enlargement, along with activation of prosurvival signaling pathways and decreased lung parenchyma cell apoptosis. …"
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article -
244
Work-life balance, perceived stress, & locus of control
منشور في 2014احصل على النص الكامل
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conferenceObject -
245
Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System
منشور في 2017"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
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article -
246
Combinatory effect of diet and exercise on brain derived neurotrophic factor expression, cognitive function and behavioral phenotypes of psychiatric disorders. (c2017)
منشور في 2017"…BDNF levels are dramatically decreased in the adult brain in response to stress and are elevated by increased exercise. …"
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masterThesis -
247
An empirical approach to understanding users' fake news identification on social media
منشور في 2021"…Findings The findings show that expertise in social media use and verification behavior have a positive impact on fake news identification, while trust in social media as an information channel decreases this identification behavior. Furthermore, results establish the mediating role of social media information trust and verification behavior. …"
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article -
248
Breast cancer cells and bone marrow mesenchymal stromal cells
منشور في 2017"…Objective The role of direct cell–cell interactions mediating selective bone metastasis by breast cancer cells (BCCs) niche is still mostly unknown. …"
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article -
249
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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250
RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
منشور في 2019"…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …"
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article -
251
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
منشور في 2013"…Hypoxia-inducible factor (HIF) mediates a broad, conserved adaptive response to hypoxia, and the HIF pathway is a potential therapeutic target in cerebral ischemia. …"
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252
Determinants of dividend payout ratio
منشور في 2014احصل على النص الكامل
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conferenceObject -
253
Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection?
منشور في 2021"…SEMA3A was not different at baseline; at hypoglycemia, SEMA3A decreased in controls only. Post-hypoglycemia, SEMA3A levels were higher in T2D versus controls. sNRP1 did not correlate with ACE2, REN or AGT. …"
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254
Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats
منشور في 2010"…Photostimulation increased BP (4 mmHg) and renal sympathetic nerve discharge (43%) while decreasing heart rate (15 bpm). Conclusions: Photostimulation of ChR2-transfected RVLM Phox2b neurons produces a vigorous stimulation of breathing accompanied by a small sympathetically mediated increase in BP. …"
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article -
255
Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
منشور في 2023"…Furthermore, the peptide inhibitor protects dopaminergic neurons from α-synuclein-mediated degeneration in hermaphroditic C. elegans and preclinical Parkinson’s disease models using female rats. …"
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256
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
منشور في 2025"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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article -
257
Deciphering the In vitro Role of microRNAs miR-21-3p and miR-222-5p In the Regulation of Clostridioides difficile Flagellin-Induced Inflammation
منشور في 2024"…Clostridioides difficile infection (CDI) induces severe intestinal inflammation, mediated partly by the NF-κB signaling pathway. Flagellin (FliC), a major component of C. difficile flagella, plays a pivotal role in host-pathogen interactions by inducing inflammation via Toll-like receptor 5 (TLR5). …"
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masterThesis -
258
miRNA-dependent regulation of STIM1 expression in breast cancer
منشور في 2019"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"
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259
Evaluation of cationic channel TRPV2 as a novel biomarker and therapeutic target in Leukemia-Implications concerning the resolution of pulmonary inflammation
منشور في 2019"…Challenging lung airway epithelial cells (AECs) with LBCs decreased (by more than 50%) transepithelial resistance (TER) denoting barrier function alteration. …"
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260
A Severe Case of Overlap of Morphea and Eosinophilic Fasciitis after Burn Injuries
منشور في 2024"…Another uncommon immune‐mediated connective tissue disease called eosinophilic fasciitis (EF) evolves to cause sclerosis and woody skin induration. …"