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COMET: A Machine-Learning Framework Integrating Ligand-Based and Target-Based Algorithms for Elucidating Drug Targets
Published 2025“…Computational methods can efficiently narrow down the candidate targets for subsequent experimental validation. We have developed a computational target-fishing method, termed COMET, which integrates ligand-based similarity scores with target-based binding scores into a random forest algorithm for target ranking. …”
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COMET: A Machine-Learning Framework Integrating Ligand-Based and Target-Based Algorithms for Elucidating Drug Targets
Published 2025“…Computational methods can efficiently narrow down the candidate targets for subsequent experimental validation. We have developed a computational target-fishing method, termed COMET, which integrates ligand-based similarity scores with target-based binding scores into a random forest algorithm for target ranking. …”
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COMET: A Machine-Learning Framework Integrating Ligand-Based and Target-Based Algorithms for Elucidating Drug Targets
Published 2025“…Computational methods can efficiently narrow down the candidate targets for subsequent experimental validation. We have developed a computational target-fishing method, termed COMET, which integrates ligand-based similarity scores with target-based binding scores into a random forest algorithm for target ranking. …”
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Types of machine learning algorithms.
Published 2024“…Thus, the objectives of this study are to develop an appropriate model for predicting the risk of undernutrition and identify its influencing predictors among under-five children in Bangladesh using explainable machine learning algorithms.…”
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Data Sheet 2_Machine learning algorithm based on combined clinical indicators for the prediction of infertility and pregnancy loss.zip
Published 2025“…The model for potential pregnancy loss was also developed using five machine learning algorithms and was based on 7 indicators. …”
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Data Sheet 1_Machine learning algorithm based on combined clinical indicators for the prediction of infertility and pregnancy loss.docx
Published 2025“…The model for potential pregnancy loss was also developed using five machine learning algorithms and was based on 7 indicators. …”
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Data Sheet 1_Predicting place of delivery choice among childbearing women in East Africa: a comparative analysis of advanced machine learning techniques.pdf
Published 2024“…</p>Method<p>The study focused on 86,009 childbearing women in East Africa. A comparative analysis of 12 advanced machine learning algorithms was conducted, utilizing various data balancing techniques and hyperparameter optimization methods to enhance model performance.…”
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Data Sheet 2_Predicting place of delivery choice among childbearing women in East Africa: a comparative analysis of advanced machine learning techniques.pdf
Published 2024“…</p>Method<p>The study focused on 86,009 childbearing women in East Africa. A comparative analysis of 12 advanced machine learning algorithms was conducted, utilizing various data balancing techniques and hyperparameter optimization methods to enhance model performance.…”
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Image 2_Construction of a clinical prediction model for osteoporosis in asymptomatic elderly population based on machine learning algorithm.tif
Published 2025“…</p>Method<p>In this study, a robust and accurate prediction model for osteoporosis was developed and validated based on machine learning and SHAP techniques. …”
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Table 1_Construction of a clinical prediction model for osteoporosis in asymptomatic elderly population based on machine learning algorithm.docx
Published 2025“…</p>Method<p>In this study, a robust and accurate prediction model for osteoporosis was developed and validated based on machine learning and SHAP techniques. …”
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Image 1_Construction of a clinical prediction model for osteoporosis in asymptomatic elderly population based on machine learning algorithm.tif
Published 2025“…</p>Method<p>In this study, a robust and accurate prediction model for osteoporosis was developed and validated based on machine learning and SHAP techniques. …”