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281
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
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282
Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis...
Published 2021“…We completed systematic reviews and did Bayesian meta-regressions for 36 causally linked health outcomes to estimate non-linear dose-response risk curves for current and former smokers. …”
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283
Antecedents and consequences on employee turnover intention in the hospitality industry in Lebanon
Published 2020“…H1 (There is an indirect relationship between PAT and Turnover) showed a significant result that when training is available employees’ intention to leave decreases. As for H2 (AC mediates the relationship between PAT and Turnover) it was supported as AC highly mediated the relationship between these two variables; it showed then when training is available, employees tend to be more committed to their organization and their intention to leave decreased. …”
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284
Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000–17
Published 2020“…More than 253 000 people did not have access to sewer or septic sanitation facilities in the city of Harare, Zimbabwe, despite 88·6% (95% UI 87·2–89·7) access overall. …”
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285
Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage
Published 2018“…Increased glucose entry into glycolysis in fibroblast senescence is mainly mediated by increased hexokinase-2. SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …”
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A comparison of peer, teacher and self-feedback on the reduction of language errors in student essays
Published 2016“…Results show that language development is mediated by source of CF, type of error, and affective factors.…”
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288
Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk
Published 2015“…Moreover, smoking inhalation increases the activity of inflammatory mediators through an increase in leukotriene synthesis essential in atherosclerosis pathogenesis. …”
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289
Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells
Published 2021“…When deprived of arginine, several types of cancers can modulate arginine synthesis mediated by the enzyme ASS1 or employ broader response mechanisms such as autophagy. …”
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290
Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018)
Published 2018“…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …”
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291
Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
Published 2020“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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292
Dietary Trichosporon mycotoxinivoron modulates ochratoxin-A induced altered performance, hepatic and renal antioxidant capacity and tissue injury in broiler chickens
Published 2021“…Dietary OTA at all the tested levels induced the hepatic and renal tissue injury as indicated by significant decreased total antioxidant capacity in these organs along with significant decreased (p ≤ 0.05) serum concentrations of total proteins and albumin. …”
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293
Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch
Published 2025“…BackgroundAtopic dermatitis (AD) is a multifaceted inflammatory skin disease characterized by chronic itch and acute itch flare (AIF), with basophils playing pivotal roles in both. VAMP7 mediates immune responses; however, its function in basophils remains undefined. …”
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294
A component analysis of positive behaviour support plans
Published 2012“…This paper investigates which components are most effective and which factors might mediate effectiveness. Method Sixty-one staff working with individuals with intellectual disability and challenging behaviours completed longitudinal competency-based training in PBS. …”
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295
Work-life balance, perceived stress, & locus of control
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296
Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System
Published 2017“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
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297
Combinatory effect of diet and exercise on brain derived neurotrophic factor expression, cognitive function and behavioral phenotypes of psychiatric disorders. (c2017)
Published 2017“…BDNF levels are dramatically decreased in the adult brain in response to stress and are elevated by increased exercise. …”
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298
An empirical approach to understanding users' fake news identification on social media
Published 2021“…Findings The findings show that expertise in social media use and verification behavior have a positive impact on fake news identification, while trust in social media as an information channel decreases this identification behavior. Furthermore, results establish the mediating role of social media information trust and verification behavior. …”
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299
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Published 2013“…Levels of HETE and inflammatory mediators were examined by LC/MS and Multiplex Immunoassay respectively. …”
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Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…Objective The role of direct cell–cell interactions mediating selective bone metastasis by breast cancer cells (BCCs) niche is still mostly unknown. …”
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