Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …”

Monitoring the Athlete Match Response: Can External Load Variables Predict Post-match Acute and Residual Fatigue in Soccer? A Systematic Review with Meta-analysis by Karim Hader (2548618)

“…For every 100-m run above 5.5 m·s⁻¹, CK activity measured 24 h post-match increased by 30% and CMJPPO decreased by 0.5%. Conversely, the total distance covered did not present any evidence of a clear relationship with any fatigue-related marker at any time-point.…”

Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up by Wahiba Elhag (5245547)

“…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …”

10-Day structured initiation protocol from multiple daily injection to hybrid closed-loop system in children and adolescents with type 1 diabetes by Goran Petrovski (129836)

“…The participants used the sensor for a median of 92% of the time and spent a median of 89% in Auto Mode. The mean HbA1c decreased from 8.2 ± 1.4% (66 ± 15.3 mmol/mol) at baseline to 6.7 ± 0.5% (50 ± 5.5 mmol/mol) at the end of the study (p = 0.017). …”

Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort by Mohamed Adil Shah Khoodoruth (14589828)

“…Multivariate analysis highlighted significant differences in platelet count, mean platelet volume (MPV), TG, HbA1c, BMI, neutrophil/lymphocyte ratio (NLR), monocyte/lymphocyte ratio (MLR), and ferritin among the groups. …”

Brain microstructural changes support cognitive deficits in HIV uninfected children born to HIV infected mothers by Yadav, Santosh K.

“…Decreased FA along with both increased and decreased MD in different brain regions was present in HUC compared to CHNM. …”
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Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making by Almutairi, Adel F.

“…Results Study participants who were invited and completed the survey were 657. The percentage mean score of participants’ attitudes and concern was 70.1 ± 16.4 and 58.3 ± 15.3 respectively. …”
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Dual-labeled trastuzumab-based imaging agent for the detection of human epidermal growth factor receptor 2 overexpression in breast cancer by Sampath, Lakshmi

“…The tumor-to-muscle ratio decreased in mice pretreated with trastuzumab and in mice injected with IRDye 800CW and (111In-DTPA)p-IgG-(IRDye800)q. …”
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Changes in Blood microRNA Expression and Early Metabolic Responsiveness 21 Days Following Bariatric Surgery by Stephen L. Atkin (6684368)

“…</p><p dir="ltr"><br></p><h3>Methods: </h3><p dir="ltr">Twenty-nine type 2 patients with severe obesity (mean BMI 46.2 kg/m²) and diabetes underwent Roux-en-Y gastric bypass (RYGB) surgery. …”

SYSTEM DYNAMICS APPROACH FOR WHOLE LIFE CYCLE COST MODELLING OF RESIDENTIAL BUILDING PROJECTS IN UNITED ARAB EMIRATES by Sadek, Ahmed

“…The applied adjusting risks are comprising three value levels. Minimum, mean, and maximum cost risks. Simulated costs under adjusting risks' levels can be presented in the same exported data sheet. …”
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Global, regional, and national burden of household air pollution, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021 by Fiona B, Bennitt

“…InterpretationAlthough the burden attributable to HAP has decreased considerably, HAP remains a substantial risk factor, especially in sub-Saharan Africa and south Asia. …”
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Conceptual Skills in Leading Change: A Competence Approach to Public Sector Leadership by JASIM, ARIF FADHEL AHMED

“…These interpretive cognitive acts of meaning construction by leaders and followers include significant elements of conceptual thinking and explanation. …”
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Implementation of corporate governance rules and procedures in lebanese firms by Elgammal, Walid

“…It also helps the organization to determine the means to achieve its objectives and monitor its performance. …”
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An Evaluation of Short-Term Effects of Different Soil Management Systems on Soil Physical, Structural and Hydraulic Properties and an Estimation and Optimization of Water Infiltrat... by Merheb, Caroline

“…In both soils, tillage application decreased the densities, the aggregate mean weight diameter, the residual moisture content, and the fine pore volumes while increased the organic matter content, the porosity, the saturated hydraulic conductivity, and the amount of large pores of undisturbed soil. …”
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Causes of blindness and vision impairment in 2020 and trends over 30 years, and prevalence of avoidable blindness in relation to VISION 2020: the Right to Sight: an analysis for th... by Jaimie D Steinmetz (18015919)

“…</p><p><br></p><h3>Methods</h3><p dir="ltr">We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. …”

Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases by Glazer, Evan

“…A meta-analysis9 found that PET had higher sensitivity rates (76%) for detection of malignant lesions than did helical CT (64%) or MRI (71%). That meta-analysis included 61 articles from 1990 to 2003. …”
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Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
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Trends in prevalence of blindness and distance and near vision impairment over 30 years: an analysis for the Global Burden of Disease Study by Rupert Bourne (603842)

“…</p><p><br></p><h3>Methods</h3><p dir="ltr">We did a systematic review and meta-analysis of population-based surveys of eye disease from January, 1980, to October, 2018. …”

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1 by Natalie C Galles (9715361)

“…Drawing from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2020, Release 1, we did a systematic analysis of global, regional, and national vaccine coverage trends using a statistical framework, by vaccine and over time.…”

The global, regional, and national burden of oesophageal cancer and its attributable risk factors in 195 countries and territories, 1990–2017: a systematic analysis for the Global... by Farin Kamangar (63964)

“…Between 1990 and 2017, age-standardised incidence decreased by 22·0% (18·6–25·2), mortality decreased by 29·0% (25·8–32·0), and DALYs decreased by 33·4% (30·4–36·1) globally. …”