Impact of inflammation, gene variants, and cigarette smoking on coronary artery disease risk by Merhi, Mahmoud

“…Moreover, smoking inhalation increases the activity of inflammatory mediators through an increase in leukotriene synthesis essential in atherosclerosis pathogenesis. …”
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Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells by Haidar, Fatemah

“…When deprived of arginine, several types of cancers can modulate arginine synthesis mediated by the enzyme ASS1 or employ broader response mechanisms such as autophagy. …”
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Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…Due to the resistance and complexity of the tumor itself, it is characterized by a low survival rate and decreased prognosis. Therefore, more selective and efficient therapeutic methods for targeting GBM are needed. …”
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Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment by Farhat, Peter

“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
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Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy by Khoury, Reine

“…The beneficial effects of exercise are mediated through the induction of the brain derived neurotrophic factor (BDNF). …”
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Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch by Zhang, Wenhao

“…BackgroundAtopic dermatitis (AD) is a multifaceted inflammatory skin disease characterized by chronic itch and acute itch flare (AIF), with basophils playing pivotal roles in both. VAMP7 mediates immune responses; however, its function in basophils remains undefined. …”
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A component analysis of positive behaviour support plans by Grey, Ian

“…This paper investigates which components are most effective and which factors might mediate effectiveness. Method Sixty-one staff working with individuals with intellectual disability and challenging behaviours completed longitudinal competency-based training in PBS. …”
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Stimulation of sphingosine 1-phosphate signaling as an alveolar cell survival strategy in emphysema by Diab, Khalil J.

“…Administration of sphingosine decreased the ceramide-to-S1P ratio in the lung and inhibited alveolar space enlargement, along with activation of prosurvival signaling pathways and decreased lung parenchyma cell apoptosis. …”
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Work-life balance, perceived stress, & locus of control by Karkoulian, Silva

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Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System by Bair, Scott

“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
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An empirical approach to understanding users' fake news identification on social media by Aoun Barakat, Karine

“…Findings The findings show that expertise in social media use and verification behavior have a positive impact on fake news identification, while trust in social media as an information channel decreases this identification behavior. Furthermore, results establish the mediating role of social media information trust and verification behavior. …”
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12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase by Amira Othman (380131)

“…Levels of HETE and inflammatory mediators were examined by LC/MS and Multiplex Immunoassay respectively. …”

Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

“…Objective The role of direct cell–cell interactions mediating selective bone metastasis by breast cancer cells (BCCs) niche is still mostly unknown. …”
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas by Tejedor, Alejandro

“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
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RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells by El Atat, Oula

“…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …”
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…Hypoxia-inducible factor (HIF) mediates a broad, conserved adaptive response to hypoxia, and the HIF pathway is a potential therapeutic target in cerebral ischemia. …”
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Determinants of dividend payout ratio by Elgammal, Walid

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Soluble Neuropilin-1 Response to Hypoglycemia in Type 2 Diabetes: Increased Risk or Protection in SARS-CoV-2 Infection? by Abu Saleh Md Moin (6189512)

“…SEMA3A was not different at baseline; at hypoglycemia, SEMA3A decreased in controls only. Post-hypoglycemia, SEMA3A levels were higher in T2D versus controls. sNRP1 did not correlate with ACE2, REN or AGT. …”

Photostimulation of Phox2b medullary neurons activates cardiorespiratory function in conscious rats by Kanbar, Roy

“…Photostimulation increased BP (4 mmHg) and renal sympathetic nerve discharge (43%) while decreasing heart rate (15 bpm). Conclusions: Photostimulation of ChR2-transfected RVLM Phox2b neurons produces a vigorous stimulation of breathing accompanied by a small sympathetically mediated increase in BP. …”
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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease by Satra Nim (11540447)

“…Furthermore, the peptide inhibitor protects dopaminergic neurons from α-synuclein-mediated degeneration in hermaphroditic C. elegans and preclinical Parkinson’s disease models using female rats. …”