Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells by Ejlal Abu-El-Rub (5168183)

“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”

The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties by Jelena Eric (21015107)

“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”

Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells by Nihal AlMuraikhi (6002234)

“…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …”

A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country by Nancy Zaghloul (14147865)

“…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…”

Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis by Fateen Ata (12217764)

“…The overall SPE-related mortality rate was 8 % (95 % CI: 5.26–10.96). …”

The effects of texting on students' spelling skills. (c2014) by Daccache, Jamayna Georges

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Essays on the effect of excess compensation and governance changes on firm value by Dah, Mustafa A.

“…Our results suggest that an increase in director excess compensation decreases the likelihood of CEO turnover, reduces the turnover-performance sensitivity, and increases managerial entrenchment. …”
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Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? by Abdalla, Eddie K.

“…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …”
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Vitamin D association with coagulation factors in polycystic ovary syndrome is dependent upon body mass index by Abu Saleh Md Moin (6189512)

“…It is reported that PCOS subjects show marked platelet dysfunction and decreased plasma fibrinolytic activity, resulting in a prothrombotic state. …”

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells by Mohamed Qasim, Al-Fahdawi

“…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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A systematic review on sequence-to-sequence learning with neural network and its models by Yousuf, Hana

“…Through introductory hunts, 790 papers, and scholarly works were found, and with the assistance of choice criteria and PRISMA methodology, the number of papers reviewed decreased to 16. Every one of the 16 articles was categorized by their contribution to each examination question, and they were broken down. …”
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The effect of soft background music, Mozart music, on the three levels of students' engagement. (c2016) by Al Bizri, Dima Bashir

“…Engagement, in its three levels, cognitive, behavioral, and affective, is vital in the learning process. One strategy that leads to active engagement is soft background music, such as Mozart music. …”
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An empirical approach to understanding users' fake news identification on social media by Aoun Barakat, Karine

“…Findings The findings show that expertise in social media use and verification behavior have a positive impact on fake news identification, while trust in social media as an information channel decreases this identification behavior. Furthermore, results establish the mediating role of social media information trust and verification behavior. …”
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Bulk passivation of perovskite films utilizing halide anion ionic liquids by Alashkar, Adnan

“…The average lifetimes obtained within one day of preparations were 79 ns, 73 ns and 275 ns for pristine perovskite, IL-I passivated perovskite and IL-Cl passivated perovskite films, respectively. …”
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Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression by Rayanah Barnawi (8737584)

“…<p dir="ltr">Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic options. …”

Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019 by Razieh, Hassannejad

“…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …”
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Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31 by Jonathan D. J. Labonne (18090841)

“…<p dir="ltr">We report a genomic and phenotypic delineation for two chromosome regions with candidate genes for syndromic intellectual disability at 12q12 and Xp22.31, segregating independently in one family with four affected members. Fine mapping of three affected members, along with six unreported small informative CNVs, narrowed down the candidate chromosomal interval to one gene LRRK2 at 12q12. …”

دور مكاتب الإصلاح والوساطة والتوفيق الأسري في الأردن في الحد من النزاعات الأسرية من وجهة نظر العاملين بها... by Al-Oqaili , Amneh Irshied

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A Modification to Enhance the Survival of the Island FDMA Flap by Adding a Skin Bridge by Salim Al Lahham (16515333)

“…Introducing first dorsal metacarpal artery flap has solved the dilemma. One drawback is that the flap is susceptible to distal necrosis, which can happen because of tight tunneling or insufficient venous drainage. …”

Impact of Exclusive Bus Lanes on Traffic Performance in Urban Areas by Abdulwahid, Amro Riyadh

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