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Malva pseudolavatera Leaf Extract Promotes ROS Induction Leading to Apoptosis in Acute Myeloid Leukemia Cells In Vitro
منشور في 2020"…Treatment of AML cell lines with M. pseudolavatera methanolic leaf extract showed a dose- and time-dependent inhibition of proliferation and a dose-dependent increase in apoptotic hallmarks such as an increase in phosphatidylserine on the outer membrane leaflet and membrane leakage in addition to DNA fragmentation. …"
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43
Safety and Effectiveness of 100 mg/kg/day Deferiprone in Patients with Thalassemia Major
منشور في 2005"…Twelve thalassemia major patients received deferiprone at a dose of100 mg/kg/day over 2 years. Transient aspartate aminotransferase increase (8 patients), gastrointestinal discomfort (3 patients) and arthralgia (2 patients) were the most commonly reported side effects. …"
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44
Hepatoprotective, Antioxidant, and Anticancer Effects of the Tragopogon porrifolius Methanolic Extract
منشور في 2015"…The highest dose of the extract (250 mg/kg) recorded a fold increase of 1.68 for SOD, 2.49 for GST, and 3.2 for CAT. …"
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45
The Anti-Tumor Effect of Flaxseed Lignan Derivatives on Different Acute Myeloid Leukemia Cancer Cells
منشور في 2020"…Moreover, Cell Death ELISA analysis showed a dose-dependent increase in apoptosis, as revealed by an increase in DNA fragmentation. …"
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masterThesis -
46
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Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
منشور في 2023"…Cannabis oil extract was administered at increasing doses of 5, 10, or 20 mg/kg to the Folic acid-treated groups for 2 weeks. …"
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masterThesis -
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Sternbergia Clusiana Bulb Ethanolic Extracts Induce Apoptosis in MCF-7 Breast Cancer Cells
منشور في 2022"…A dose-dependent increase in apoptosis via induced DNA fragmentation was revealed via Cell Death ELISA as well as an increase in cellular fragmentation using flow cytometry. …"
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masterThesis -
51
The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000)
منشور في 2000"…The mean levodopa dose was reduced by 90% (p < 0.01), while the mean dopamine agonist dose was increased by 15% from preoperative level. …"
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masterThesis -
52
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Aqueous urtica dioica leaves extract inhibits proliferation of acute myeloid leukemia cells in vitro
منشور في 2017"…To confirm apoptosis, AnnexinV/PI dual staining method was performed showing a time- and dose-dependent increase in the number of cells in the early and late apoptosis stage. …"
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54
Bone Benefits of Fish Oil Supplementation Depend on its EPA and DHA Content
منشور في 2019"…<div><p>The preventive effect of high-dose (9%) regular-fish oil (FO) against bone loss during aging has been demonstrated, but the effects of a low-dose (1%–4%) of a highly purified concentrated FO (CFO) has not been elucidated. …"
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Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
منشور في 2011"…Increasing the dose to 500 mg/kg body weight caused a significant decrease in stool water content. …"
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56
β-2-himachalen-6-ol protects against skin cancer development in vitro and in vivo
منشور في 2017"…Results β-2-himachalen-6-ol showed a dose-dependent decrease in cell survival with an IC50 and IC90 of 8 and 30 μg/ml, respectively. …"
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57
The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013)
منشور في 2016"…Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. An increase in the production of both cytokines is usually associated with neoplastic transformation. …"
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masterThesis -
58
Dietary Curcumin Nanoparticles Improve Growth Performance, Oxidative Status and Immune Response of European Seabass (<i>Dicentrarchus Labrax</i>)
منشور في 2024"…A noticeable decrease (P<0.05) in malondialdehyde (MDA) and considerable upregulation of hepatic insulin-like growth factor 1 (IGF1) and interleukin-1beta (IL-1β) mRNA levels were found in CURNPs-supplemented fish in a dose-dependent manner. …"
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Association Between Three-Months Vitamin D Supplementation and Depressive Symptomatology incidence among Saudi Arabian Adults
منشور في 2022"…Furthermore, the change between both groups was significantly different (-7.61 ±4.03 in the Vitamin D group, -3.50±1.54 in the control group; p=<0.001) Conclusion: The present study shows thata 50.000 IU/week dose of vitamin D supplementation for 3 months was enough to increase vitamin D levels beyond sufficient and decrease depression symptoms in Saudi Arabian Adults. …"
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masterThesis
