Effect of the natural sequencing read placement uncertainty on euploid sample group number of false-positive trisomy 21 cases. by Priit Paluoja (6927959)

Table1_Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos.xlsx by Akifumi Ijuin (16817115)

“…</p><p>Discussion: Our results indicate that aneuploid cells decrease in human embryos post-implantation, and mtDNA mutations might induce low mitochondrial function and influence the development of post-implantation embryos with not only aneuploidy but also euploidy. …”

Table5_Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos.DOCX by Akifumi Ijuin (16817115)

“…</p><p>Discussion: Our results indicate that aneuploid cells decrease in human embryos post-implantation, and mtDNA mutations might induce low mitochondrial function and influence the development of post-implantation embryos with not only aneuploidy but also euploidy. …”

Table_2_A Novel Predictive Model to Estimate the Number of Mature Oocytes Required for Obtaining at Least One Euploid Blastocyst for Transfer in Couples Undergoing in vitro Fertili... by Sandro C. Esteves (5143712)

“…The estimated predicted probabilities of a mature oocyte turn into a euploid blastocyst decreased progressively with female age and was negatively modulated overall by use of testicular sperm across age (p < 0.001). …”

Table_1_A Novel Predictive Model to Estimate the Number of Mature Oocytes Required for Obtaining at Least One Euploid Blastocyst for Transfer in Couples Undergoing in vitro Fertili... by Sandro C. Esteves (5143712)

“…The estimated predicted probabilities of a mature oocyte turn into a euploid blastocyst decreased progressively with female age and was negatively modulated overall by use of testicular sperm across age (p < 0.001). …”

Table_3_A Novel Predictive Model to Estimate the Number of Mature Oocytes Required for Obtaining at Least One Euploid Blastocyst for Transfer in Couples Undergoing in vitro Fertili... by Sandro C. Esteves (5143712)

“…The estimated predicted probabilities of a mature oocyte turn into a euploid blastocyst decreased progressively with female age and was negatively modulated overall by use of testicular sperm across age (p < 0.001). …”

Data_Sheet_1_A Novel Predictive Model to Estimate the Number of Mature Oocytes Required for Obtaining at Least One Euploid Blastocyst for Transfer in Couples Undergoing in vitro Fe... by Sandro C. Esteves (5143712)

“…The estimated predicted probabilities of a mature oocyte turn into a euploid blastocyst decreased progressively with female age and was negatively modulated overall by use of testicular sperm across age (p < 0.001). …”

Both monosomies and trisomies decrease cellular fitness. by Dorine C. Hintzen (12988183)

DataSheet_1_Impact of endometrial compaction on reproductive outcomes after cryotransfer of euploid embryos in a modified natural cycle: protocol for a prospective cohort study.pdf by Esperanza De la Torre Perez (17363236)

“…Inclusion criteria are: 18 to 50 years of age, with primary or secondary infertility, subjected to endometrial preparation in a modified natural cycle for transfer of a genetically euploid blastocyst, from their own oocyte or oocyte donation, with a normal uterine cavity. …”

MtDNA replacement in human oocytes with MRR-SCCT procedure. by Xiaoyu Liao (8161995)

MtDNA carryover removal and SCC integraty by MRR manipulation in mouse oocytes. by Xiaoyu Liao (8161995)

Whole genome sequencing analysis of FLC-evolved and engineered strains. by Xin Zhou (54275)

MtDNA residual levels and chromosomal copy numbers in mouse SCC transferred blastocysts. by Xiaoyu Liao (8161995)

Trisomy detection accuracy of tested NIPT software tools across different sequencing depths. by Priit Paluoja (6927959)

Genome instability in STRIPAK complex mutants. by Patricia P. Peterson (20291306)

“…<p>(A) Read depth analyses from whole-genome sequencing of the WT/WT (CnLC6683) parental diploid strain and heterozygous mutant diploid strains. The WT/WT genome is euploid, while <i>PPH22/pph22</i>Δ and <i>MOB3/mob3</i>Δ strains exhibit multiple instances of segmental and whole chromosome aneuploidy, with dark blue and orange highlighting regions/chromosomes with increased and decreased read depth, respectively. …”

Image1_Preimplantation genetic testing for complex chromosomal rearrangements: clinical outcomes and potential risk factors.PDF by Dun Liu (674970)

“…Type B exhibited the lowest rate of euploid embryos at only 6.7%, followed by type A at 11.6% and type C at 14.0%, although the differences were not significant (p = 0.182). …”

Table1_Preimplantation genetic testing for complex chromosomal rearrangements: clinical outcomes and potential risk factors.PDF by Dun Liu (674970)

“…Type B exhibited the lowest rate of euploid embryos at only 6.7%, followed by type A at 11.6% and type C at 14.0%, although the differences were not significant (p = 0.182). …”

Table_7_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…</p>Results<p>Results highlight specific alterations of THF with a median concentration ratio DS/control of 2:3, a decrease of a necessary molecule perfectly consistent with a chromosomal dosage effect. …”

Table_8_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…</p>Results<p>Results highlight specific alterations of THF with a median concentration ratio DS/control of 2:3, a decrease of a necessary molecule perfectly consistent with a chromosomal dosage effect. …”

Table_3_One-carbon pathway metabolites are altered in the plasma of subjects with Down syndrome: Relation to chromosomal dosage.xlsx by Beatrice Vione (10734998)

“…</p>Results<p>Results highlight specific alterations of THF with a median concentration ratio DS/control of 2:3, a decrease of a necessary molecule perfectly consistent with a chromosomal dosage effect. …”