DataSheet_1_Dual targeting of glutamine and serine metabolism in acute myeloid leukemia.pdf by Kanwal M. Hameed (18386853)

“…<p>Acute myeloid leukemia (AML) is a heterogeneous hematological malignancy characterized by disrupted blood cell production and function. …”

Table1_Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos.xlsx by Akifumi Ijuin (16817115)

“…</p><p>Discussion: Our results indicate that aneuploid cells decrease in human embryos post-implantation, and mtDNA mutations might induce low mitochondrial function and influence the development of post-implantation embryos with not only aneuploidy but also euploidy. …”

Table5_Mitochondrial DNA mutations can influence the post-implantation development of human mosaic embryos.DOCX by Akifumi Ijuin (16817115)

“…</p><p>Discussion: Our results indicate that aneuploid cells decrease in human embryos post-implantation, and mtDNA mutations might induce low mitochondrial function and influence the development of post-implantation embryos with not only aneuploidy but also euploidy. …”

Supplementary Material for: Regulation of miR-126 and miR-122 Expression and Response of Imatinib Treatment on Its Expression in Chronic Myeloid Leukemia Patients by AliBeg M.M. (11278041)

“…The expression of miR-126 was not conclusive when compared in different clinical stages of the CML disease as it showed a decreased expression in patients with accelerated phase compared to chronic phase (mean fold change = 0.03 and 0.27, respectively), but patients with chronic phase and blastic phase had comparable expression (mean fold change = 0.27 and 0.24, respectively). …”

EF-24 treatment induces distinct gene expression changes in Kasumi-1 cells. by Ajeet P. Singh (22298432)

EF-24 treatment disrupts key molecular pathways associated with cell survival, proliferation, and viability. by Ajeet P. Singh (22298432)

EF-24 induces significant transcriptional changes in K-562 cells. by Ajeet P. Singh (22298432)

EF-24 treatment alters gene expression profiles in HL-60 cells. by Ajeet P. Singh (22298432)

Distinct and shared gene expression patterns among leukemia cell lines following EF-24 treatment. by Ajeet P. Singh (22298432)

CSF1R and IL-8 mediated signaling affect PDAC portal blood CTC proliferation, cluster formation, and apoptosis. by Juan Pablo Arnoletti (12275290)

Inhibition of CSF1R, IL-8, and IL-34 reduces T cell anergy in PortalBMC <i>ex vivo</i> cultures. by Juan Pablo Arnoletti (12275290)

IFNγ from ASFV-specific CD4+CD8+ T cells induces TNF-production by myeloid cells. by Laia Bosch-Camós (14093985)

“…The fold decrease was calculated by dividing percentages of TNF-producing cells without IFNγ blockage by percentages of TNF-producing cells with IFNγ blockage. …”

Tun increases mitochondrial fission, inflammatory cell infiltration, and decreased ER-mitochondria interaction in neonatal rat lungs. by Kirkwood A. Pritchard Jr. (13449794)

“…The decreased expressions of GRP75 (0.5±0.2-fold, p = 0.006767, n = 5) and acyl-CoA synthetase long-chain family member 4 (ASCL4; 0.3±0.1-fold, p<0.001, n = 5) indicate a decreased interaction between ER and mitochondria by Tun. …”

DataSheet_1_Autolysosomal activation combined with lysosomal destabilization efficiently targets myeloid leukemia cells for cell death.doc by Harshit Shah (9375656)

“…</p>Results<p>Our analyses demonstrated several-fold higher constitutive autolysosomal activity in ML cells as compared to human CD34⁺ hematopoietic cells. …”

DataSheet1_Potential drug-drug interaction of olverembatinib (HQP1351) using physiologically based pharmacokinetic models.docx by Zhiheng Yu (2433805)

“…The predicted results suggest that 1) strong, moderate, and mild CYP3A4 inhibitors (which have some overlap with CYP2C9 inhibitors) may increase olverembatinib exposure by approximately 2.39-, 1.80- to 2.39-, and 1.08-fold, respectively; strong, and moderate CYP3A4 inducers may decrease olverembatinib exposure by approximately 0.29-, and 0.35- to 0.56-fold, respectively 2); olverembatinib, as a “perpetrator,” would have no or limited impact on CYP1A2, CYP2B6, CYP2C9, CYP2C19, and CYP3A4 enzyme activity 3); systemic exposure of olverembatinib in liver function injury with Child-Pugh A, B, C may increase by 1.22-, 1.79-, and 2.13-fold, respectively. …”

The pathway analysis of 348 genes in the hematopoietic cell lineage pathway (Fig 6A) using the KEGG pathway database and DAVID software. by Souma Suzuki (18554923)

The pathway analysis of 348 genes in the cytokine-cytokine receptor interaction pathway (Fig 6A) using the KEGG pathway database and DAVID software. by Souma Suzuki (18554923)

DataSheet_1_Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models.pdf by Meike Kaehler (4561306)

“…(Gln61Lys) variant provided a strong benefit for CML cells under TKI exposure visible by increased cell number (6.2-fold, p < 0.001) and decreased apoptosis (-25%, p < 0.001), proving the functionality of our approach. …”

Table_1_Clonal evolution in tyrosine kinase inhibitor-resistance: lessons from in vitro-models.xlsx by Meike Kaehler (4561306)

“…(Gln61Lys) variant provided a strong benefit for CML cells under TKI exposure visible by increased cell number (6.2-fold, p < 0.001) and decreased apoptosis (-25%, p < 0.001), proving the functionality of our approach. …”

Impact of IBD gene candidate ORFs on the THP-1 transcriptome. by Mohamad Karaky (8910497)