Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management by Tarraf, Vanessa

“…The shifting of the negative charge (-17.22± 5.99 mV) of the uncoated liposomes to the positive charge (13.17± 3.34 mV) of the coated one approved the success of the coating. …”
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miRNA-dependent regulation of STIM1 expression in breast cancer by Rashmi P. Kulkarni (18618634)

“…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …”

Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Valery L Feigin (5320574)

“…During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). …”

Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology by Senyuk, Mihail

“…Features of transmission line maintenance were used to increase accuracy of estimation. …”
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Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…We previously showed that inhibition of the platelet-derived growth factor receptor (PDGFR) blocks the survival and migration of medulloblastoma cells. …”
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Optimization of Vapor Compression Refrigeration Cycles with Clathrate Hydrates Thermal Energy Storage by Gadalla, Akram Mohamed

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Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 by Austin, Carter

“…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …”
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Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms by ALBLOOSHI, ROUDHA KHALID ABDULLA

“…Implementing a 6KV surge protector for higher-wattage lights significantly reduced defect rates by 0.5%. This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …”
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Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models by Ben Romdhane, Haifa

“…Furthermore, results demonstrated that the probability of severe damage increases with decreasing water oxygenation and with increasing temperature, light, salinity, acidity and nutrient levels. …”
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α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain by Eid, Fady

“…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…”
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Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon by Mokhbat, Jacques M.

“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity by Imran Ramzan (15430807)

“…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …”

Evaluation of the durability and shielding properties of high-strength concrete incorporating locally available materials and carbon additives by Othman, Obaida

“…The inclusion of steel fibers (FLDUNE) increased 28-day compressive and flexural strengths by 3.5 and 22%, respectively, and reduced shrinkage and creep by 25 and 10%. …”
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Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 by Joseph L Ward (9715619)

“…Annual percentage decrease in all-cause mortality rate since 1990 in adolescents aged 15–19 years was 1·3% in males and 1·6% in females, almost half that of males aged 1–4 years (2·4%), and around a third less than in females aged 1–4 years (2·5%). …”

Secrecy Performance of a RIS-Assisted Wireless Network: A Comprehensive Analysis Under Outdated CSI by Tasneem Alshamaseen (22392382)

“…This resilience indicates that the system can reduce channel estimation frequency to reconfigure the RIS, thus decreasing overall system overhead and complexity and improving energy efficiency. …”

Applying value-based strategies to accelerate access to novel cancer medications: guidance from the Oncology Health Economics Expert Panel in Qatar (Q-OHEP) by Anas Hamad (9545771)

“…<h3>Background</h3><p dir="ltr">In line with global trends, cancer incidence and mortality may have decreased for specific types of cancer in Qatar. …”

Orofacial Clefts by El Baba, Nada

“…We found no significant differences in the proliferative abilities of the patient-derived cells and the healthy cells. The striking difference in behavior was related to cell migration, whereby the patient-derived cells showed decreased motility, increased adhesion, and a general loss of polarity compared to the healthy cells. …”
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Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro by Najem, Sonia A.

“…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
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A Risk-Based Multi-Objective Modeling Approach to the Preventive Maintenance Process of Roof Waterproofing System at Airports by Shehab, Bahaa

“…The purpose of this study is to: (a) determine current waterproofing systems and components of concrete roofs at airports, (b) explore frequently used techniques to design optimal preventive maintenance policies, and (c) derive an optimal preventive multi-objective risk-based maintenance strategy via simulation that can diminish failure costs, thereby decreasing the system’s overall maintenance costs. …”
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