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401
Selective induction of apoptosis in T-cell acute lymphoblastic leukemia by pristimerin through dual PI3K/AKT pathway inhibition and ROS generation
منشور في 2025"…Prist significantly increases reactive oxygen species (ROS) levels and depletes glutathione (GSH), leading to mitochondrial dysfunction and cytochrome c release. …"
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402
Protein arginine methyltransferase 5 (PRMT5) activates WNT/β‐catenin signalling in breast cancer cells via epigenetic silencing of DKK1 and DKK3
منشور في 2023"…<p></p><div> <p>Protein arginine methyltransferase 5 (PRMT5) activity is dysregulated in many aggressive cancers and its enhanced levels are associated with increased tumour growth and survival. However, the role of PRMT5 in breast cancer remains underexplored. …"
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403
Inositol 1,4,5-Trisphosphate Receptors in Hypertension
منشور في 2018"…This involves a phenotypic switch of VSMCs as well as an alteration of cytoplasmic Ca<sup>2+</sup> signaling machinery, a phenomena tightly related to the aging process. Several lines of evidence implicate changes in expression/function levels of IP<sub>3</sub>R isoforms in the development of hypertension, VSMC phenotypic switch, and vascular aging. …"
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404
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
منشور في 2021"…SNG treatment increased Bax/Bcl-2 ratio, which contributed to a leaky mitochondrial membrane leading to cytochrome c release accompanied by caspase activation. …"
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405
Maternal Body Mass Index and Recommended Gestational Weight Gain in a Middle Eastern Setting
منشور في 2023"…</p><h3>Results</h3><p dir="ltr">The mean maternal age was 29.7 ± 5.5 years, prepregnancy BMI was 27.5 ± 5.8 kg/m2, GWG was 9.58 kg ± 6.87 kg and gestational age at birth was 38.5 ± 1.9 weeks. …"
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406
Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
منشور في 2023"…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …"
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407
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
منشور في 2025"…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …"
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408
Cytotoxicity of [HuArgI (co)-PEG5000]-induced arginine deprivation to ovarian Cancer cells is autophagy dependent
منشور في 2019"…Ovarian cancer cell lines were negative for annexinV staining while showing loss of membrane integrity and absence of caspase activation, indicating caspase-independent, non-apoptotic cell death. …"
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409
1,2,4-Trimethylbenzene Transformation Reaction Compared With Its Transalkylation Reaction With Toluene Over USY Zeolite
منشور في 2020"…The apparent activation energies were found to decrease as follows: E-transalkylation > E-isomerization > E-disproportionation.…"
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410
Drug-free phototherapy of superficial tumors
منشور في 2021"…While previous data proved its inherent cytotoxicity, this study is the first to explore the use of a commercially available, high-intensity white LED light (24.5 mW.cm−2) as a treatment for skin tumors. After a 9-h exposure in vitro, the viability of Human Malignant Melanoma cells (A375) decreased by around 70%. …"
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411
Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon
منشور في 2011"…Antiplatelet activity was investigated in vitro using the adenosine 5′-diphosphate (ADP)-induced platelet aggregation bioassay. …"
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412
Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample
منشور في 2020"…The prevalence of DM increased from 40.4 to 46.5% in patients hospitalized for HF. In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …"
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413
Custom foot orthoses improve performance, but do not modify the biomechanical manifestation of fatigue, during repeated treadmill sprints
منشور في 2022"…Regardless of footwear condition, mean horizontal forces, step frequency, vertical and leg stiffness decreased from sprint 1 to sprint 8 (all <i>P</i> < 0.001). …"
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414
Oral contraceptive pills and possible adverse effects
منشور في 2014احصل على النص الكامل
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415
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416
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417
Solar hydrogen production via thermochemical magnesium oxide – Magnesium sulfate water splitting cycle
منشور في 2020"…Further increment in the solar-to-fuel energy conversion efficiency up to 62.5% is possible if 50% of the heat recuperation is applied.…"
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418
Effect of Acute and Chronic Moderate Red or White Wine Consumption on Fasted and Postprandial Lipemia in the Rat
منشور في 2006"…Fasted rats, in the acute study, were loaded intragastrically with 5 ml of an olive oil emulsion (30% w/v) in the presence or absence of wine (8% v/v ethanol), and either mesenteric lymph or blood was collected 3 h postprandially. …"
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419
Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
منشور في 2024"…Experimental samples S1, S3, S5 and S10 were prepared from polymer pellets that were stored for 1,3,5 and 10-year time duration respectively. …"
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420
Carotid artery revascularization through a radiated field
منشور في 2003"…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …"
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