Angiotensin II AT1 receptor internalization, translocation and de novo synthesis modulate cytosolic and nuclear calcium in human vascular smooth muscle cells by Sleiman, S.

“…Overexpression of hAT1R and hAT1R GFP decreased both basal cytosolic and nuclear Ca2+. In normal hVSMCs and low hAT1R GFP overexpressing hVSMCs, Ang II (10 15 to 10 4 M) induced a dose-dependent sustained increase of [Ca]c and [Ca]n with an EC50 near 5 × 10 11 and 5 × 10 9 M, respectively. …”
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Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors by Yu Wang (12152)

“…Liquid (bounce fraction; BF < 0.2) at RH > 80 % and nonliquid behaviour (BF > 0.8) at RH < 30 % were observed, with a liquid-to-nonliquid transition with decreasing RH between 30 % and 80 %. This RH-dependent phase behaviour (RH_{BF=0.2, 0.5, 0.8}) increased towards a maximum, with an increasing organic–inorganic mass ratio (MR_org_/inorg) during SOA formation evolution in all investigated VOC systems. …”

Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon by Mokhbat, Jacques M.

“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We observed ATP depletion under OGD vs. hypoxia and propose that ATP depletion enhances translational suppression, overcoming the selective synthesis of HIF concurrent with global decreases in protein synthesis in hypoxia. Taken together, these findings biochemically characterize a practical reporter for monitoring HIF-1α levels and support a novel model for HIF regulation in an in vitro model of human ischemia.…”
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Reply to Comments by Kakkar and Dahiya by Chahine, Elias B.

“…TO THE EDITOR: Chahine, Karaoui, and Mansour1 reviewed the efficacy and safety of bedaquiline in the treatment of adults with pulmonary multidrug-resistant tuberculosis (MDR-TB) and generally agree with the comments made by Kakkar and Dahiya.2 Bedaquiline was approved by the Food and Drug Administration based largely on results from phase 2 studies using sputum conversion as a surrogate marker for efficacy rather than long-term mortality data.2 Bedaquiline was shown to be associated with an unfavorable side effect profile, including an unexplained increased risk of mortality, QT prolongation, and elevated liver function tests.2 However, it is important to acknowledge that bedaquiline is the first novel drug to be approved for the treatment of TB in more than 4 decades and the communities devastated by MDR-TB are in desperate need for more options to manage their patients. …”
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In Vitro and In Vivo Effects of Lebanese Cannabis Oil Against Acute Myeloid Leukemia (AML) by Lteif, Anthony

“…WEHI-3 cells were treated with increasing concentrations of COE to determine the IC50 after 24, 48 and 72-hours post treatment. …”
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Towards electric digital twin grid: Technology and framework review by Md. Mhamud Hussen Sifat (17337913)

“…Thus, the power grid transmission loss and location of the overheated line and power connection missing can be detected in addition decision-making and self-healing can possible. …”

Effects of paternal and chronological age on BEGAIN methylation and its possible role in autism by Ramya Potabattula (4401160)

“…<p dir="ltr">Children from old fathers carry an increased risk for autism spectrum (ASD) and other neurodevelopmental disorders, which may at least partially be mediated by paternal age effects on the sperm epigenome. …”

Simulating blood vessel scaffolds by Nature Research (16552612)

“…According to their simulations, the amount of shear stress is highest at the endoluminal strut surface, where the stent comes into contact with the inner lining of the vessels, but very low at the areas where blood flows in and out of the device. …”

Tailoring the deposition of MoSe₂ on TiO₂ nanorods arrays via radiofrequency magnetron sputtering for enhanced photoelectrochemical water splitting by Yahia H. Ahmad (14340210)

“…Compared to pure TiO₂ NRs, the heterojunction nanostructured assembly displayed excellent spectral and photoelectrochemical properties, including more surface oxygen vacancies, enhanced visible-light absorption, higher photocurrent response, and decreased charge transfer resistance. In particular, the sample synthesized by sputtering of MoSe₂ for 90 s, i.e., MoSe₂@TiO₂-90 s, depicted the highest current density (1.86 mA cm⁻² at 0.5 V vs. …”

Control of the Speed of a Light-Induced Spin Transition through Mesoscale Core-Shell Architecture by Slimani, Ahmed

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Solar Technology and District Cooling System in a Hot Climate Regions: Optimal Configuration and Technology Selection by Rabah Ismaen (18387189)

“…The PVT-DCS configuration has the lowest operation cost and the highest environmental performance by decreasing the global warming potential by 89.5%. The T-DCS configuration becomes economically competitive only at high electricity tariffs.…”

Enhanced thermoelectric properties of Bi₂Te_2.55Se_0.45 nanocomposites using eco-friendly Eocene Midra Shale palygorskite nanofillers: A sustainable... by Farah M. El-Makaty (14157090)

“…However, adding higher amounts (0.1, 0.5, and 1) decreased the electrical and thermal conductivities due to the dominant effect of bulky precipitates in increasing the scattering of charge carriers and phonons. …”

An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH₄-CO₂-H₂S by Hani Ababneh (9218272)

“…The model predictions for the solidification points of 5 different mixtures were within the acceptable error when compared to the experimental data available in the literature. …”

Past and future climate effects on population structure and diversity of North Pacific surfgrasses by Ana I. Tavares (6942986)

“…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …”

Therapeutic targeting of the TPX2/TTK network in colorectal cancer by Hibah Shaath (5599658)

“…The growth potential of CRC cells under 3-dimensional (3D) conditions was assessed using Matrigel. STRING database (v11.5) and Ingenuity Pathway Analysis (IPA) tool were used for network and pathway analyses. …”

Associating learning technology to sustain the environment through green mobile applications by Haraty, Ramzi A.

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Kinetics and adsorption of metolachlor and atrazineand the conversion products (deethylatrazine,deisopropylatrazine, hydroxyatrazine) in the soilprofile of a river basin by Vryzas, Z.

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Acute pain management and assessment by Zeitoun, Abeer A.

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Functionalization of reverse osmosis membrane with graphene oxide to reduce both membrane scaling and biofouling by Mohammad Y. Ashfaq (14152290)

“…After functionalization, the membrane surface properties were improved as the water contact angle was reduced from 41.7 ± 4.5⁰ to 26.9 ± 0.9⁰ demonstrating improvement in hydrophilic properties besides decreasing membrane surface roughness. …”