Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…However, we did not observe the same changes in the other KO lines. …"

Validation of Polygenic Risk Scores for Coronary Heart Disease in a Middle Eastern Cohort Using Whole Genome Sequencing حسب Mohamad Saad (214545)

"…However, the 9p21 locus did not replicate. Six suggestive (<i>P</i><10−5) new loci/genes with plausible biological function were identified (eg, <i>CORO7</i>, <i>RBM47</i>, <i>PDE4D</i>). …"

Tranexamic acid for the prevention of blood loss after cesarean section: an updated systematic review and meta-analysis of randomized controlled trials حسب Huzaifa Ahmad Cheema (16328980)

"…TXA was associated with a beneficial effect in our secondary outcomes including decline in hemoglobin levels and the need for additional uterotonic agents. TXA increased the risk of non-thromboembolic adverse events but, based on limited data, did not increase the incidence of thromboembolic events. …"

The Effects of the COVID-19 Pandemic on Undergraduate Students’ Stress and Anxiety in a University in the UAE حسب Alfalasi, Khulood

"…This study argues and claims that the COVID-19 pandemic did not have a direct impact as an epidemic on student academic stress. …"
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The distribution of toxic sources in Louisiana حسب Djoundourian, Salpie Sarkis

"…A distance gradient analysis indicates that as distance from the nearest toxic source increases, the mean percentage of blacks in the community decreases and the mean percentage of whites increases. …"
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Hyperaminoacidaemia at postprandial levels does not modulate glucose metabolism in type 2 diabetes mellitus حسب Bassil, M.

"…Whereas phosphorylation of AKTSer473, AKTThr308 mTORSer2448 and rpS6Ser235/236 increased (p < 0.05) with elevated amino acids, that of IRS-1Ser636/639 and IRS-1Ser1101 did not change. …"
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Identification of Cancer Stem Cells in Human Gastrointestinal Carcinoid and Neuroendocrine Tumors حسب Gaur, Puja

"…Although many primary cell lines failed to grow, CNDT96 ALDH+ cells formed spheres in anchorage-independent conditions, whereas ALDH- cells did not. CNDT2.5 ALDH+ cells formed spheres, whereas ALDH- cells did not. …"
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Risk factors for stoma outlet obstruction: systematic review and meta-analysis حسب Ali Toffaha (18111886)

"…Although age was assessed as a potential risk factor, it did not show a statistically significant association with SOO (OR 1.69, 95% CI 0.44–6.54).…"

Topical treatments for atopic dermatitis (eczema): Systematic review and network meta-analysis of randomized trials حسب Derek K., Chu

"…With moderate- to high-certainty evidence, group 5 TCS improved 6—among the best for 3; group 4 TCS and delgocitinib improved 4—among the best for 2; ruxolitinib improved 4—among the best for 1; group 1 TCS improved 3—among the best for 2. These interventions did not increase harm. Crisaborole and difamilast were intermediately effective, but with uncertain harm. …"
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Macular ultrastructural features in amblyopia using high-definition optical coherence tomography حسب Al-Haddad, Christiane Elias

"…Also, amblyopic eyes demonstrated a shallow foveal pit compared with normal fellow eyes. Mean foveal thickness was significantly increased in amblyopic (228.56 µm) versus fellow eyes (221.72 µm), p=0.03. …"
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Experimental and Analytical Investigations of the Use of Groove-Epoxy Anchorage System for Shear Strengthening of RC Beams Using CFRP Laminates حسب Mohamed, Khalid Mustafa Elradi

"…The developed models predicted the experimental shear-strength of the tested RC beams with a good level of accuracy, with an average mean absolute percent error (MAPE) = 3.31% and 6.68%, normalized mean square error (NMSE) = 0.072, 0.523, and coefficient of determination R2 = 0.964, 0.691, for plates and sheets, respectively.…"
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IS security menace حسب Balozian, Puzant

"…It is widely believed in IS security literature that enforcing IS security policy compliance on employees through various means is the solution for security effectiveness. …"
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Postprandial hyperaminoacidaemia overcomes insulin resistance of protein anabolism in men with type 2 diabetes حسب Bassil, M.

"…Results In Hyper-2 vs Hyper-1 clamps, leucine flux (2.99 ± 0.16 vs 2.62 ± 0.06 μmol kg [fat-free mass (FFM)]−1 min−1), rates of synthesis (2.31 ± 0.15 vs 1.98 ± 0.06) and breakdown (2.38 ± 0.16 vs 2.00 ± 0.07) were higher (p < 0.05), but leucine oxidation and net balance did not differ. In Hyper-3 vs Hyper-2 clamps, leucine flux and synthesis and oxidation rates increased markedly as did net balance (0.84 ± 0.09 vs −0.07 ± 0.04 μmol [kg FFM]−1 min−1, p < 0.0001). …"
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A novel phosphorylated STAT3 inhibitor enhances T cell cytotoxicity against melanoma through inhibition of regulatory T cells حسب Abou-Ghazal, Mohamed K.

"…The p-STAT3 inhibitor WP1066 enhanced CD3+ (which contained Tregs) but not CD8+ T cell cytotoxicity against human A375 melanoma cells, indicating that this p-STAT3 blockade agent did not directly activate CD8+ T cells. Furthermore, the p-STAT3 inhibitor did not enhance the cytotoxicity of CD3+CD25− T cells (from which Tregs were excluded), indicating that the enhanced cytotoxicity of WP1066 is secondary to its inhibition of Tregs. …"
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Pharmacist-driven antimicrobial stewardship interventions in patients with COVID-19: a scoping review حسب Z. G. Nasr (17785694)

"…Studies that reported antimicrobial stewardship (AMS) interventions performed by pharmacists in COVID-19 patients were included. Articles that did not report outcomes or did not mention pharmacists in the intervention were excluded. …"

Outcomes of drain versus no drain in total knee arthroplasty: a retrospective cohort study حسب Anas Albasha (17765964)

"…The aim of this study is to compare the outcomes of patients who received suction drains versus those who did not, focusing on blood loss, blood transfusion need, and length of hospital stay.…"

The impact of scoliosis surgery on pulmonary function in spinal muscular atrophy: a systematic review حسب Abduljabber Alhammoud (14152503)

"…Respiratory and spine-based complications were common. Given the available evidence, the following GRADE C recommendations were made: (1) surgery is most often associated with decreases in pulmonary function; (2) the impact of surgery on pulmonary function is variable, but does not improve over pre-operative baseline; (3) surgery may result in a decreased rate of decline in pulmonary function post-operatively. …"

Notes total mesorectal excision (TME) for patients with rectal neoplasia حسب Chouillard, E.

"…A median of 17 nodes (range 12–81) was retrieved per specimen. Mean length of hospital stay was 10 days (range 4–29 days). …"
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The effect of Dopamine Agonists on patients with advanced Parkinson's disease subjected to subthalamic deep brain stimulation. (c2000) حسب Jabre, Mazen Gerges

"…The mean levodopa dose was reduced by 90% (p < 0.01), while the mean dopamine agonist dose was increased by 15% from preoperative level. …"
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An experimental measurement of corona discharge using laser Dopplervelocimetry حسب Belhadj, C.A.

"…The corona wind velocity was measured by means of a laser Doppler velocimetry system implemented and calibrated in the laboratory. …"
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