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381
Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models
Published 2025“…ACSS2 inhibition significantly reduced the expression of pro-inflammatory cytokines such as Interleukin 8 (IL-8), IL-1β, and TNF-α, and attenuated activation of NF-κB and MAPK signaling pathways, as evidenced by decreased phosphorylation of p65 and ERK/MEK. These findings highlight a pro-inflammatory role for ACSS2 in IBD and identify it as a potential therapeutic target, warranting further validation in advanced models, including patient-derived organoids and in vivo systems.…”
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masterThesis -
382
NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides
Published 1981“…The structure, however, does not allow one to differentiate between electronic and steric effects in decreasing the affinity of the iron for a sixth axial ligand.…”
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383
Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon
Published 2008“…The rates of disorders peaked one month post-war and decreased over one year. …”
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384
Waterpipe Tobacco Smoke Nicotine Mediates Resilience to Chronic Stress by Activating BDNF Signaling
Published 2020“…The involvement of brain-derived neurotrophic factor signaling in the nicotine-mediated effects was assessed with the tropomyosin receptor kinase B (TRKB) inhibitor, ANA-12. …”
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masterThesis -
385
The Effect of DJ-1 on Invasion and Invadopodia Formation in Glioblastoma Multiforme
Published 2020“…Glioblastoma multiform (GBM) is one of the most aggressive malignant brain tumors. …”
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masterThesis -
386
Breast cancer cells and bone marrow mesenchymal stromal cells
Published 2017“…Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
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387
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388
Hemodynamics of small aneurysm pairs at the internal carotid artery
Published 2012“…For each case, aneurysms are separated from the parent artery and three models are reconstructed, one with two aneurysms and the other two models with only one of the two aneurysms. …”
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389
Electrochemical and thermodynamic study on the corrosion performance of API X120 steel in 3.5% NaCl solution
Published 2020“…The overall results revealed that PEI significantly decreases the corrosion rate of API X120 steel with inhibition efficiency of 94% at a concentration of 100 μmol L<sup>−1</sup>. …”
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390
Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…These positive outcomes are mediated through the induction of the expression of a growth factor, brain derived neurotrophic factor (BDNF), in the hippocampus. …”
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masterThesis -
391
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
Published 2011“…We previously showed that inhibition of the platelet-derived growth factor receptor (PDGFR) blocks the survival and migration of medulloblastoma cells. …”
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392
An empirical evaluation of the technology cycle time indicator as ameasure of the pace of technological progress in superconductortechnology
Published 1999“…The measure assumes that the more recent the age of the cited patents, the more quickly one generation of inventions is replacing another. …”
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393
Conflicts Employee-Employee
Published 2012“…The data was collected within a period of two weeks through one-to-one interview. The participants represented the eight departments with a manager and an officer from each department. …”
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394
Barriers of Additive Manufacturing Adoption in United Arab Emirates Automotive Supply Chain
Published 2023“…The United Arab Emirates (UAE) is one of the leading countries, in the Middle East, for Additive Manufacturing (AM). …”
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395
PROACT: Parallel multi-miner proof of accumulated trust protocol for Internet of Drones
Published 2022“…In such networks, swarms of UAVs cooperate in executing one or more missions to achieve the application's objectives. …”
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396
Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells
Published 2021“…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …”
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masterThesis -
397
Delineating the molecular mechanisms of hippocampal neurotoxicity induced by chronic administration of synthetic cannabinoid AB-FUBINACA in mice
Published 2024“…Additionally, we showed that AB-FUBINACA significantly decreased the expression of NR1, an important functional subunit of glutamate/NMDA receptors and closely implicated in the development of toxic psychosis. …”
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398
Dicarbonyl stress, protein glycation and the unfolded protein response
Published 2022“…An optimized inducer of Glo1 expression, trans-resveratrol and hesperetin combination, normalized increased MG concentration, corrected insulin resistance and decreased low grade inflammation in overweight and obese subjects. …”
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399
Resilience of UAE high-rise buildings to climate change: Impacts of projected climate changes on annual energy demands.
Published 2020“…This study has revealed that the derived future weather files daily dry-bulb temperatures are increasing throughout the years, while the daily relative humidity ratio and global horizontal solar radiation values are marginally decreasing from the present values. …”
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400
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”