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Location matters: spatial dynamics of tumor-infiltrating T cell subsets is prognostic in colon cancer
Published 2024“…Spatial distribution analysis elucidated that proliferative T cells, characterized by Ki67 expression, and Granzyme B-expressing T cells were predominantly located within the tumor epithelium. We demonstrated an increase in immune cell density and a decrease in the distance of CD3<sup>+</sup>CD8<sup>+</sup> T cells to the nearest tumor cell, in the immune active, ICR High, immune subtypes. …”
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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64
Chemical, rheological, and sensory properties of wheat biscuits fortified with local buckwheat
Published 2023“…The samples with <i>F</i>. tataricum demonstrated greater amounts of fiber and ash while the samples made of soft wheat flour were rich in carbohydrates. …”
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Phase II National Study: Job Satisfaction and Workplace Environment Among Community Pharmacists in Lebanon: Pre and Post Economic Crisis
Published 2024“…Average weekly working hours decreased from 59.2 hours in Phase 1 to 49.8 hours in Phase II. …”
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masterThesis -
66
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…Western blot analysis showed significant decrease in stem cell markers SOX-2 and Oct-4, and tumorigenic protein HMGA1, whereas it showed significant increase in apoptotic markers cleaved PARP and cleaved caspase-3. …”
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masterThesis -
67
Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells
Published 2014“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
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Influence of natural gas composition on adsorption in calcite Nanopores: A DFT study
Published 2021“…The results of the simulation calculations showed that as the nanopore diameter decreases, the adsorption energy increases exponentially due to the geometry of the smallest pore that increases the affinity of the molecules to the surface. …”
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Targeting the MAP kinase pathway in astrocytoma cells using a recombinant anthrax lethal toxin as a way to inhibit cell motility and invasion
Published 2016“…However, astrocytoma cells that were treated with LeTx showed a significant decrease in cell motility as seen by wound healing as well as random 2D motility in serum. …”
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The anti-cancer effect of the pentane fraction of Daucus carota oil extract is mediated through cell cycle arrest and an increase in apoptosis
Published 2013“…We indeed determined that the PF treatment led to a decrease in p-ERK as compared to total ERK levels, whereas the level of phosphorylated Akt was not affected. …”
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Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy
Published 2020“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
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masterThesis -
72
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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Economics of hydrogen production and liquefaction by geothermal energy
Published 2012“…The results show that the cost of hydrogen production and liquefaction decreases as the geothermal water temperature increases. …”
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Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…We find that monthly shrinkage rates have a pronounced structured variability around the channel network with the shrinkage rate systematically decreasing farther away from the channels. This pattern of shrinkage is predominantly attributed to a deeper active layer enhancing near-surface connectivity and storage and greater vegetation density closer to the channels leading to increased evapotranspiration rates. …”
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Tabu search based circuit optimization
Published 1998“…Such a strategy leads to sizable circuit speed improvement with minimum increase in the overall circuit capacitance. Compared to earlier approaches, the presented technique produces circuits with remarkable increase in speed (greater than 20%) for very small increase in overall circuit capacitance (less than 3%)…”
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The Effect of Auditor Characteristics on the Quality of Segment Disclosures of Diversified Firms
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doctoralThesis -
77
CEO gender and managerial entrenchment
Published 2020“…We find that the presence of female CEO decreases the turnover-performance sensitivity, increases the E-index, and inflates CEO compensation. …”
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Antitumor activity of β-2-himachalen-6-ol in colon cancer is mediated through its inhibition of the PI3K and MAPK pathways
Published 2017“…The SW1116 colon cancer cell line was treated with HC (1, 5, 10 and 25 μg/ml) and cell viability was evaluated with WST 1 assay kit. …”
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Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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Urban Geometry: The Effect of Height Diversity and Buildings Configuration on Thermal Performance and Cooling Load at Urban Scale. A Case Study in Dubai / UAE
Published 2018“…The variation along the short direction of the urban block has a greater positive effect and the saving in cooling energy consumption reaches 4.6 %. …”
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