Showing 1 - 20 results of 3,808 for search '(((( i large decrease ) OR ( ((b marked) OR (a marked)) decrease ))) OR ( a marked decrease ))', query time: 0.42s Refine Results
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    <b>Effect of Marked Weight Loss on Adipose Tissue Biology in People with Obesity and Type 2 Diabetes</b> by Dmitri Samovski (305400)

    Published 2025
    “…</p><p dir="ltr"><b>Results: </b>Weight loss: <a href="" target="_blank">i) </a><a href="" target="_blank">decreased adipose tissue </a>expression of genes related to extracellular matrix remodeling; ii) decreased adipose tissue expression of SERPINE 1 which encodes plasminogen activator inhibitor-1 (PAI-1); iii) did not decrease adipose tissue immune cell content or expression of genes involved in inflammation; iv) decreased adipose tissue ceramide content; v) decreased plasma <a href="" target="_blank">PAI-1 </a>and leptin concentrations and increased plasma high-molecular weight (HMW) adiponectin; and vi) decreased plasma small extracellular vesicle (sEV) concentration and the sEV content of microRNAs proposed to inhibit insulin action, and completely reversed the inhibitory effect of plasma sEVs on insulin signaling in myotubes.…”
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    ROC analysis to mark selectivity results in mostly mixed-selective units. by Thomas S. Wierda (22404198)

    Published 2025
    “…<p><b>a</b> Adding a modulatory current to selective units based on the ROC method results in no significant effects for choice selective units. …”
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