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Lamin-B protein marks the onset of physiological decline in young adult male <i>Drosophila</i>.
Published 2022Subjects: -
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MAb binding to JR-FL gp160ΔCT E168K+N189A in BN-PAGE “shifts”.
Published 2023“…The asterisk (*) marks a ~220kDa observed with b12 and 15e, possibility arise from decreased lateral stability during MAb binding.…”
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<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b>
Published 2025“…Age-corrected data revealed decreased islet frequency and increased inter-islet distances in the type 1 diabetes pancreas. …”
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Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia.
Published 2022“…(<b>D)</b> Mann–Whitney test, <i>N</i> (WT) = 142 cells from 2 mice, <i>N</i> (KO) = 83 cells from 1 mouse. ****: <i>p</i> < 0.0001. …”
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Decreased <i>Bgl-</i>FaNaC expression in the left parietal ganglion following <i>S</i>. <i>mansoni</i> infection.
Published 2023“…See values in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0011249#pntd.0011249.t001" target="_blank">Table 1</a>. <b>e-g:</b> Decreased <i>Bgl</i>-FaNaC hybridization on the ventral surface of the left parietal ganglion in infected specimens. …”
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Deletion of Ssp2 or/and Gsk3/Gsk31 markedly suppressed CLZ, TER or CoCl<sub>2</sub>-induced Sre1 activity.
Published 2020“…<p>The Δ<i>ssp2</i>, Δ<i>gsk3</i>Δ<i>gsk31</i>, Δ<i>ssp2</i>Δ<i>gsk3</i>, Δ<i>ssp2</i>Δ<i>gsk31</i> or Δ<i>ssp2</i>Δ<i>gsk3</i>Δ<i>gsk31</i> cells showed a significant decrease in Sre1 activity and delay in the peak rising of the SRE2 reporter stimulated with 8 μg/ml CLZ (A)<sub>,</sub> 8 μg/ml TER (B) or 0.32 mM CoCl<sub>2</sub> (C). …”
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<b>Effects of marked weight loss induced by gastric bypass surgery or low-calorie diet alone on postprandial glucose disposal in type 2 diabetes</b>
Published 2025“…<p dir="ltr">We used a dual (intravenous and oral) glucose tracer protocol to evaluate rates of glucose appearance into the circulation, insulin-mediated glucose disposal (IMGD), and non-insulin-mediated glucose disposal (NIMGD) for four hours after consumption of a mixed meal in people with obesity and type 2 diabetes before and after marked (~20%) weight loss, induced by behavioral diet therapy (BDT, n=11) or Roux-en-Y gastric bypass (RYGB) surgery (n=9).…”
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