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large decrease » marked decrease (Expand Search), large increases (Expand Search), large degree (Expand Search)
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Cinacalcet administered early in the inactive phase markedly decrease parathyroid Ki-67 index.
Published 2025Subjects: -
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Simplified scheme illustrating the inhibitory effect of nNOS on the PPP during the initiation of GSIS.
Published 2025“…<p>1) A marked increase in glucose concentration results in a large accumulation of the released insulin at the exocytotic sites of nNOS-associated insulin granules (denoted as orange circles on insulin granules) in the PPP. …”
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Deletion of microglial NKCC1 markedly impacts on baseline cell morphology and alters transformation to reactive microglia.
Published 2022“…(<b>C)</b> NKCC1 mRNA levels in isolated NKCC1 KO microglia was markedly reduced in comparison to WT cells. (<b>D, E)</b> NKCC1 protein expression in a large number of randomly sampled NKCC1 KO microglia cells is markedly reduced compared to WT cells. …”
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The proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases in <i>APC</i>-mutant colon tissues from FAP patients.
Published 2020“…Results show that, in normal crypts, the distribution and proportion of cells staining for ALDH1 and CGA are very similar. In contrast, in <i>APC</i>-mutant tissues from FAP patients, the proportion of ALDH+ cells progressively increases while CGA+ cells markedly decreases. …”
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Persistence of β-cell responsiveness for over two years in autoantibody-positive children with marked metabolic impairment at screening
Published 2022“…</p> <p><strong>Results:</strong> Longitudinal analyses revealed annualized AUC C-peptide increases in non-progressors vs. decreases in progressors (p≤0.026 for DPT-1 and TNPTP). …”
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Violin plots of the best fit modelled distributions of times to clinical outcome over the course of the pandemic for category A.
Published 2021“…For both hospitalisation to death and infection to death, the mean time was lowest in the first wave, and there was a marked increase over the summer months.</p>…”
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