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<i>S</i>. Typhimurium coordinates protein synthesis with protein folding capacity.
Published 2024Subjects: -
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Decreased Notch pathway activity in isolated MAFs.
Published 2021“…</b> Quantification of gene expression of the Notch pathway components in MAF vs. FF2441 by <i>PCR Array</i>. The <i>Notch1</i>, <i>Notch4</i>, <i>Dll1</i>, <i>Hes-1</i> and <i>Hey-1</i> genes were significantly downregulated (<2-fold) in MAFs (* <i>P</i><0.01). …”
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FTY720 treatment decreased tumor growth in a xenograft model of hepatoblastoma.
Published 2019“…There was a trend toward decreased Ki67 staining in FTY720-treated tumors (p = 0.29). …”
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mTORC1 hyperactivation led to a decreased autophagic activity in the podocytes.
Published 2020“…<p>(<b>A</b>) Primary cultured podocytes were isolated from <i>Tsc2</i><sup>Δ<i>podocyte</i></sup> and wild-type controls, followed by western blot analyses of TSC2, phospho-4EBP1, LC3B type II, p62, phospho-ULK1, and β-tubulin. …”
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Diabetic kidney shows decreased klotho expression.
Published 2021“…<p>(a) Representative images of the kidney from normal and diabetic biopsies showing the decreased klotho expression in diabetic podocytes by IHC. …”
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The decrease or inhibition of Hsp90 induced REST degradation.
Published 2019“…(D) The level of REST dramatically reduced in differentiated SH-SY5Y cells treated with GA (1 μM) or PU-H71 (50 nM) at 24 h. (E) The REST level decreased by GA more than 50% and (F) PU-H71 more than 80%, respectively. …”
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