The Transition from a Compensatory Increase to a Decrease in C-peptide During the Progression to Type 1 Diabetes and Its Relation to Risk by Heba M Ismail (9568748)

“…This change was mostly attributable to change in the late AUC C-peptide response (i.e., 60-to-120-minute AUC C-peptide). Median Index60 values of  DPT-1 (1.44) and TNPTP (1.05) progressors to type 1 diabetes 1.5 years pre-diagnosis (time of transition from increasing to decreasing AUC C-peptide) were used as thresholds to identify individuals at high risk for type 1 diabetes in the full cohort at baseline (5-year risk of 0.75-0.88 for those above thresholds). …”

Decreasing trends in HbA1c are visible when using the average HbA1c for each dataset for T1Ds, but not T2Ds. by Hans F. Dias (14486401)

CHIKV-infected primary joint tissue fibroblasts display decreased MHC-I cell surface expression. by Brian C. Ware (8544672)

<i>RTTN</i>-mutated organoids exhibit decreased proliferation and increased cell death at early stages. by Justine Guguin (9088672)

Cells expressing nsP2 inefficiently present antigen and have decreased levels of cell surface MHC-I. by Brian C. Ware (8544672)

Effects of leucettines as DYRK1A inhibitors on cell cycle and cyclin D1 level. by Barbara Pucelik (2988795)

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Cell nuclear volume decreases under increasing osmotic pressure. by Adele Khavari (7378082)

Effects of DYRK1A inhibitors on isolated mouse islets. by Barbara Pucelik (2988795)

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The influence of selected leucettines on insulin production by 3D MIN6 spheroids. by Barbara Pucelik (2988795)

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Decreased <i>Bgl-</i>FaNaC expression in the visceral ganglion following <i>S</i>. <i>mansoni</i> infection. by Laura C. Vicente-Rodríguez (16437803)

“…Dunnett’s <i>post hoc</i> test: *, <i>p</i> < 0.05. See values in <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0011249#pntd.0011249.t001" target="_blank">Table 1</a>. …”

Predictive value of RVT1 for the decreased RV ejection fraction (RVEF) and poor outcome in pulmonary arterial hypertension (PAH). by Ryotaro Asano (11767131)

“…We defined a change of +3% or −3% (between baseline and follow-up over 12 months) as an increased or decreased RVEF, respectively. …”

<i>E</i> values weakly decrease with absolute latitude. by Dimitrios—Georgios Kontopoulos (9530566)

“…Note that values on the vertical axis increase exponentially. The data underlying this figure are available at <a href="https://doi.org/10.6084/m9.figshare.12816140.v1" target="_blank">https://doi.org/10.6084/m9.figshare.12816140.v1</a>.…”

Cell-penetrating 15mer peptides decrease the proliferation and viability of cancer cells. by Pavan Kumar Puvvula (10495853)

Decreased <i>Bgl-</i>FaNaC expression in the left parietal ganglion following <i>S</i>. <i>mansoni</i> infection. by Laura C. Vicente-Rodríguez (16437803)

“…<p><b>a-c:</b> Decreased <i>Bgl</i>-FaNaC hybridization on the dorsal surface of the left parietal ganglion in infected specimens. …”

Cabozantinib significantly decreases tumor volume and prolongs survival in SCNPC PDX models. by Mark P. Labrecque (10011469)

Treatment with low doses of GI254023X causes a mild decrease in ADAM10 surface expression that correlates with a marked impairment of HCV infectivity. by Belén Carriquí-Madroñal (17396512)

Effects of 254- or 222-UVC exposure on <i>C</i>. <i>elegans</i> motility. by Kaoru Okamoto Yoshiyama (14526661)

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CMS121 and C75 reduce the infectivity of HSV-1 viral particles. by Camilla Albano (16446679)

The influence of leucettines as DYRK1A inhibitors on insulin, C-peptide, and glucagon production by MIN6 cells. by Barbara Pucelik (2988795)

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HFD induces LDs and decreases ER and mitochondria in nephrocytes. by Aleksandra Lubojemska (10746241)

“…See <b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001230#pbio.3001230.s006" target="_blank">S1 Data</a></b> for details of <i>p</i>-values and the type of statistical model used for all graphs in this study. …”