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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
Published 2022“…In this regard, the recent SARS-CoV-2 alpha, beta, and gamma variants (B.1.1.7, B.1.351, and P.1 lineages, respectively) are of great significance in that they contain several mutations that increase their transmission rates as evident from clinical reports. …”
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apoA2 correlates to gestational age with decreased apolipoproteins A2, C1, C3 and E in gestational diabetes
Published 2021“…</p><h3>Results</h3><p dir="ltr">apoA2, apoC1, apoC3 and apoE were lower in women with GDM compared with control women (p=0.0019, p=0.0031, p=0.0002 and p=0.015, respectively). apoA1, apoB, apoD, apoH, and apoJ levels did not differ between control women and women with GDM. …”
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Corrigendum: Decreased interfacial dynamics caused by the N501Y mutation in the SARS-CoV-2 S1 spike:ACE2 complex
Published 2022“…The MOV files 5 to 8 are now removed from the <b>Supplementary Material</b>.</p><p dir="ltr">In the published article, there was also an error in the “<b>Materials and Methods</b>” section, sub-section “<i>ACE2-S1-RBD Molecular Dynamics Simulation Trajectory Analysis</i>”, <b>paragraph 1</b>. …”
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Novel Wire Gripper for Robotics Picking of Small Green Parts From Powder Bed of Binder Jet Metal Additive Manufacturing
Published 2025“…The adaptable gripper system fits different part geometries to decrease the chance of component deformation or fracturing. …”
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Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
Published 2022“…<p dir="ltr">This study presents comprehensive energetic, exergetic, exergoeconomic, and economic (4E) performance analyses for four direct oxy‐combustion (DOC) supercritical carbon dioxide (sCO2) power cycles at design, off‐design, and part‐load conditions. These cycles include the dual recuperator cycle (DRC), intercooling cycle (ICC), partial intercooling cycle (PIC), and reheating cycle (RHC). …”
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Part II.: Dissimilar friction stir welding of nickel titanium shape memory alloy to stainless steel – microstructure, mechanical and corrosion behavior
Published 2021“…Tensile testing of the weld showed a small initial plateau region, characteristic of shape memory alloys (SMAs) arising from NiTi part of the weld. Importantly, the transformation temperatures of NiTi, measured by differential scanning calorimetry (DSC) from different weld zones, varied by no more than 4 °C. …”
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Using B<sub>4</sub>C Nanoparticles to Enhance Thermal and Mechanical Response of Aluminum
Published 2017“…It was observed that the density decreased and porosity increased with an increase in B4C content in aluminum matrix. …”
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Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…Studies related to B19V prevalence in the Middle East and North Africa (MENA) region and other parts of Asia are very scarce. …”
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Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…<h3>Background</h3><p dir="ltr">Combating <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/hepatitis-virus" target="_blank">viral hepatitis</a> is part of the UN Sustainable Development Goals (SDGs), and WHO has put forth hepatitis B elimination targets in its Global Health Sector Strategy on Viral Hepatitis (WHO-GHSS) and Interim Guidance for Country Validation of Viral Hepatitis Elimination (WHO Interim Guidance). …”
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The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells
Published 2019“…In the current study, treatment of A549 cells with Pb significantly induced cell apoptosis as evidenced by increasing a) the percentage of cells underwent apoptosis determined by flow cytometry and b) p53 mRNA level. Pb treatment induced oxidative stress by a) increasing the formation of reactive oxygen species and b) decreasing GSTA1 mRNA levels. …”
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The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series
Published 2024“…In multivariable Poisson interrupted time series regression, the COVID-19 lockdown was associated with a 27% decrease in the monthly numbers of HIV tests (IRR 0.73, 95%CI 0.72–0.73), a 25% decrease in HIV positive tests (IRR 0.75, 95%CI 0.71–0.79), and a 43% reduction in ART initiations (IRR 0.57, 95%CI 0.55–0.60). …”
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Disrupting the α-synuclein-ESCRT interaction with a peptide inhibitor mitigates neurodegeneration in preclinical models of Parkinson’s disease
Published 2023“…We find that the most potent peptide inhibitor disrupts the direct interaction between the C-terminal region of α-synuclein and CHarged Multivesicular body Protein 2B (CHMP2B), a component of the Endosomal Sorting Complex Required for Transport-III (ESCRT-III). …”
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Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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Microwave-Assisted Solvothermal Synthesis of Mo-Doped TiO<sub>2</sub> with Exceptional Textural Properties and Superior Adsorption Kinetics
Published 2022“…Additionally, Mo-TiO<sub>2</sub> expressed enhanced adsorption kinetics for RhB compared to state-of-the-art adsorbents. The introduced synthesis procedure holds a grand promise for the versatile synthesis of metal-doped TiO<sub>2</sub> nanostructures with outstanding physicochemical properties.…”
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Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts
Published 2020“…In an in-vitro cell model, these compounds decreased the insoluble phosphorylated α-syn and aggregation. …”
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