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201
Effects of COVID-19 on Autism Spectrum Disorder in Qatar
منشور في 2024"…Parents also reported decreased access to family and social support networks, as well as decreased quality of clinical and community support. …"
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202
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
منشور في 2025"…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…"
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203
Hedgehog Signaling Inhibition by Smoothened Antagonist BMS-833923 Reduces Osteoblast Differentiation and Ectopic Bone Formation of Human Skeletal (Mesenchymal) Stem Cells
منشور في 2019"…BMS-833923, a SMO antagonist/Hedgehog inhibitor, exhibited significant inhibitory effects on osteoblast differentiation of hMSCs reflected by decreased ALP activity, in vitro mineralization, and downregulation of osteoblast-related gene expression. …"
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204
Changes in the burden and underlying causes of heart failure in the Eastern Mediterranean Region, 1990–2019: an analysis of the Global Burden of Disease Study 2019
منشور في 2023"…FindingsIn contrast with the decreasing trend of HF burden globally, EMR showed an increasing trend. …"
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205
Optimal management, prevalence, and clinical behavior of saddle pulmonary embolism: A systematic review and meta-analysis
منشور في 2022"…The overall SPE-related mortality rate was 8 % (95 % CI: 5.26–10.96). …"
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206
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
منشور في 2025"…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …"
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207
A 5-year trend in the use of sodium-glucose co-transporter 2 inhibitors and other oral antidiabetic drugs in a Middle Eastern country
منشور في 2022"…Among SGLT2is, empagliflozin prescriptions showed an increase from 537 (10.65%) to 2881 (34.40%) compared to dapagliflozin, which decreased by the end of 2018 from 4505 (89.35%) to 5494 (65.6%).…"
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208
The Use of Cutting-Stone-Slurry-Waste in Engineering Practice
منشور في 2010"…Results indicated that mixing the clay soil with cutting stone slurry waste increased the max dry density, and decreased the optimum water content percent and the plasticity index. …"
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209
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
منشور في 2022"…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …"
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210
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
منشور في 2021"…<p dir="ltr">Recent years have witnessed major progress in development of novel therapeutic agents such as chemotherapy, targeted therapy and immune checkpoint inhibitors for breast cancer. However, cancer-related death remains high especially in triple-negative breast cancer (TNBC) due limited therapeutic options. …"
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211
Properties and Microstructure Distribution of High-Performance Thermal Insulation Concrete
منشور في 2020"…This material allows for better thermal insulation properties, thus decreasing the energy usage within the life cycle of the concrete structure. …"
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212
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
منشور في 2025"…<p dir="ltr">Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …"
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213
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
منشور في 2019"…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…"
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214
TCAD Simulation and Analysis of Selective Buried Oxide MOSFET Dynamic Power
منشور في 2019"…Increasing power dissipation may lead to decreasing system effciency and lifetime. The BULK metal oxide semiconductor field-effect transistor (MOSFET) has relatively high power dissipation and low frequency response due to its internal capacitances. …"
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215
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216
Novel proteins implicated in lipid metabolism disorders
منشور في 2016"…After feeding, its expression is decreased, promoting the uptake of dietary lipids in fat tissue. …"
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217
Characterization of Contusive Spinal Cord Injury by Monitoring Motor-Evoked Potential
منشور في 2024"…Results: The results indicate that the relative MEP power spectral decreased to 11% and 22% in the left and right hindlimbs, respectively, during the first week post-SCI. …"
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218
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
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219
Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates
منشور في 2023"…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …"
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220
Frugal innovation for sustainable rural development
منشور في 2023"…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …"