A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate حسب Geethakumari, Anupriya M

"…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …"
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Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar حسب Doua Abdelrahman (17280667)

"…<div><p>Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) region and other parts of Asia are very scarce. …"

The Trace Element Composition of Size Fractionated Suspended Particulate Matter Samples from the Qatari EEZ of the Arabian Gulf: The Role of Atmospheric Dust حسب Oguz Yigiterhan (14151006)

"…The excess concentrations, relative to average dust, for most elements (except Cd) decreased with distance from shore, which may be due to differences in biology, currents, proximity to the coast or interannual processes.…"

Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice حسب Charlotte Rinne (18766966)

"…In aged mice, CR attenuated trabecular bone loss, suggesting that CR may revert some aspects of age-related bone dysfunction. Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …"

Appropriateness of gentamicin therapeutic drug monitoring at a Middle Eastern tertiary hospital setting: a retrospective evaluation and quality audit حسب Fatima Khalifa Al-Sulaiti (14152056)

"…Inappropriate sampling time relative to the last dose was captured in 31% (<i>n</i> = 18) of the cases. …"

Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model حسب Haissam Abou-Saleh (497840)

"…However, potential side effects related to ChNP toxicity remain the major limitation hampering their wide application. …"

Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity حسب Mohammed R. Shaker (10316180)

"…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …"

Qatar’s Evolving National Identity in Schools: A Twitter Perspective from 2015 to 2019 حسب Aisha Mohammed Al-Mansoor (20433395)

"…While the overall school twitter activity decreased over the years, the percentage of tweets by schools on nationalism remained high throughout the years, suggesting that it has remained an important topic post-blockade. …"

Driving and hypoglycemia حسب Stephen Beer (5480411)

"…Hypoglycemia is one of the major complications related to diabetes treatment. Many large studies have shown an increased risk of hypoglycemia with tight blood sugar control. …"

Non-diabetic ketoacidosis secondary to primary hyperthyroidism حسب Abdulrahman F. Al-Mashdali (17148316)

"…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …"

Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells حسب Mohamed Qasim Al-Fahdawi (17844209)

"…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …"

Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy حسب Ajaz A. Bhat (12984701)

"…Overall, this is a relatively unexplored field that could provide crucial insights into tumor immunology and encourage the effective application of modulatory cytokine-chemokine therapy to EC.…"

Trace element composition of size-fractionated suspended particulate matter samples from the Qatari Exclusive Economic Zone of the Arabian Gulf: the role of atmospheric dust حسب Oguz Yigiterhan (14151006)

"…The excess concentrations, relative to average dust, for most elements (except Cd) decreased with distance from the shore, which may be due to differences in biology, currents, proximity to the coast, or interannual processes.…"

Monitoring the Athlete Match Response: Can External Load Variables Predict Post-match Acute and Residual Fatigue in Soccer? A Systematic Review with Meta-analysis حسب Karim Hader (2548618)

"…For every 100-m run above 5.5 m·s⁻¹, CK activity measured 24 h post-match increased by 30% and CMJPPO decreased by 0.5%. Conversely, the total distance covered did not present any evidence of a clear relationship with any fatigue-related marker at any time-point.…"

PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development حسب Sahar I. Da’as (9631717)

"…Altogether, we report a novel pathogenic PGAP3 variant associated with unique phenotypic hallmarks, which may be related to the gene’s novel role in brain morphogenesis and neuronal wiring.…"

Global, regional, and national burden of respiratory tract cancers and associated risk factors from 1990 to 2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Hedyeh Ebrahimi (7321358)

"…Global age-standardised incidence rates of tracheal, bronchus, and lung cancer decreased by 7·4% (−16·8 to 1·6) and age-standardised incidence rates of larynx cancer decreased by 3·0% (−10·5 to 5·0) in males over the past decade; however, during the same period, age-standardised incidence rates in females increased by 0·9% (−8·2 to 10·2) for tracheal, bronchus, and lung cancer and decreased by 0·5% (−8·4 to 8·1) for larynx cancer. …"

Dynamic stretching alone can impair slower velocity isokinetic performance of young male handball players for at least 24 hours حسب Monoem Haddad (5345357)

"…In conclusion, testing-induced knee extensor isokinetic impairments were counterbalanced by DS, however the hip flexion DS could have produced minor muscle damage for at least 24-hours decreasing knee flexor forces and power at 60°.s^-1. …"

Basophil-VAMP7 is a vital regulator of skin barrier integrity and chronic itch حسب Zhang, Wenhao

"…VAMP7 knockout also decreased IL-4 and LTC4 release from basophils. Additionally, OSM downregulated barrier proteins and upregulated pruriceptors in keratinocytes; however, these effects were reversed by SC144, which restored skin barrier function in AIF without affecting itch response in either model. …"
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Prediction of critical total drawdown in sand production from gas wells: Machine learning approach حسب Fahd Saeed Alakbari (10701871)

"…The RSM correlation decreased the average absolute percent relative error (AAPRE) by 12.7% compared to all published correlations' AAPRE of 22.6%–30.4%. …"

Algal-algal bioflocculation enhances the recovery efficiency of Picochlorum sp. QUCCCM130 with low auto-settling capacity حسب Imen Saadaoui (14159025)

"…Results showed that self-settlement capacity increased with cell size and can be indirectly related to a decreased zeta potential of larger cells which enhances the Van der Waals attractive forces. …"