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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…MG activated the intrinsic pathway of apoptosis, with decrease of mitochondrial and spliceosomal proteins. …”
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122
Impact of birth weight to placental weight ratio and other perinatal risk factors on left ventricular dimensions in newborns: a prospective cohort analysis
Published 2024“…PW correlated with IVSs (p=0.019), while the longest placental diameter was linked to a decrease in LV internal dimension during diastole (LVIDd) (estimate=−0.07, p=0.039), LV mass (estimate=−0.11, p=0.024), and LV mass/volume (estimate=−0.55, p=0.005).…”
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123
Phase state of secondary organic aerosol in chamber photo-oxidation of mixed precursors
Published 2021“…Liquid (bounce fraction; BF < 0.2) at RH > 80 % and nonliquid behaviour (BF > 0.8) at RH < 30 % were observed, with a liquid-to-nonliquid transition with decreasing RH between 30 % and 80 %. This RH-dependent phase behaviour (RH<sub>BF=0.2, 0.5, 0.8</sub>) increased towards a maximum, with an increasing organic–inorganic mass ratio (MR<sub>org</sub><sub>/inorg</sub>) during SOA formation evolution in all investigated VOC systems. …”
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124
Case report: Safety and efficacy of voxelotor in a patient with sickle cell disease and stage IV chronic kidney disease
Published 2022“…<p dir="ltr">Sickle cell disease (SCD) is a heterogeneous group of inherited disorders characterized by the production of sickle hemoglobin which is less soluble than an adult or fetal hemoglobin. Voxelotor is a hemoglobin S polymerization inhibitor that has been approved for sickle cell disease treatment in the adult and adolescent populations. …”
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125
Intravenous administration of gold nanoparticles in rats exhibit alterations in sphingomyelins, bile acids, sphingolipids, and cholesterol esters levels
Published 2024“…Duplicate serum samples were collected 24 h post-dosing, and comprehensive metabolite profiling was performed using liquid chromatography-mass spectrometry (LC-MS/MS) and flow injection analysis-mass spectrometry (FIA-MS/MS). …”
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126
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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127
Durability of Cardiometabolic Outcomes Among Adolescents After Sleeve Gastrectomy: First Study with 9-Year Follow-up
Published 2022“…</p> <h2>Results</h2> <p>Follow-up rates were 57.53%, 82.87%, 85.24%, 83.92%, and 83.33% at the five time points. The preoperative mean body mass index (BMI) (45.60 ± 6.50 kg/m2) decreased at year 1 (30.04 ± 4.96 kg/m2, P=0.001) and was maintained up to 9 years (30.20 ± 3.92 kg/m2, P = 0.001). …”
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128
Peripheral inflammatory and metabolic markers as potential biomarkers in treatment-resistant schizophrenia: Insights from a Qatari Cohort
Published 2024“…Our findings indicated elevated body mass index (BMI) and triglyceride (TG) levels in both patient groups compared to controls. …”
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129
Trends of the Dementia Burden in South Asia: An Analysis of 2021 Global Burden of Disease Study
Published 2025“…The analysis evaluated trends in ADoD incidence, prevalence, mortality, and DALYs across five South Asian countries, focusing on health risk factors, including high body mass index, behavioral and metabolic risks.</p><h3>Results</h3><p dir="ltr">A slight decrease in incidence rates from 80.57 to 79 per 100,000 was observed, alongside a significant increase in mortality rates from 14.11 to 17.2 per 100,000. …”
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130
Energy saving potential analysis applying factory scale energy audit – A case study of food production
Published 2023“…The CO2 harmful emissions were also decreased. Additionally, it is estimated that switching from the proposed motors to energy-efficient motors will cost less overall over time, saving around 3472.314 JD/month or 0.33576/year on average. …”
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131
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”
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132
Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
Published 2020“…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…”
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133
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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134
Hypertension in Childhood Nephrotic Syndrome
Published 2019“…Although the prevalence of HTN in SSNS is less documented than in SRNS, recent studies reported high prevalence in both. …”
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135
Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes
Published 2023“…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …”
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136
A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media
Published 2024“…<p dir="ltr">Greywater recycling provides a means to address rising water demand with reduced environmental impact due to its abundance and lightly polluted nature. …”
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137
Mortality and socio-economic outcomes among patients hospitalized for stroke and diabetes in the US: a recent analysis from the National Inpatient Sample
Published 2021“…In those patients, the mean (SD) age slightly decreased from 70 (13) years to 69 (13) years (p-trend < 0.001). …”
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138
Diabetes-related cardiovascular and economic burden in patients hospitalized for heart failure in the US: a recent temporal trend analysis from the National Inpatient Sample
Published 2020“…In patients with HF and DM, mean (SD) age slightly decreased from 71 (13) to 70 (13) years, in which 47.5% were males in 2005 as compared with 52% in 2014 (p trend < 0.001 for both). …”
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139
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…However, EMG measurements showed significant reductions in average EMG power, total time, dominant frequency, and cumulative muscle workload after training. Additionally, the mean power spectral density of the EMG signal decreased notably post-training. …”
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140
Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
Published 2023“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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