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481
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
Published 2025“…The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. …”
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482
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
Published 2025“…<p dir="ltr">Colorectal cancer (CRC) is the second leading cause of cancer-related mortality worldwide. While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …”
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483
SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs
Published 2019“…Our results revealed that these selected chalcone analogs increased dopamine levels in the rat hepatoma (H4IIE) cells and decreased the relative mRNA expression of the MAO-B enzyme.…”
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484
On-site workshop investment problem: A novel mathematical approach and solution procedure
Published 2023“…These temporary OSWs are cost-effective, leading to decreasing the material handling cost and project makespan, which indicates their important role as a part of a construction project. …”
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485
Annual performance assessment of an off‐grid and self‐sufficient sustainable climate refuge for hot arid climates
Published 2023“…The electrical efficiency of the photovoltaic cells decreases from 16.87% to 15.24% with an increase in cell temperature from 309 K to 315 K. …”
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486
Frugal innovation for sustainable rural development
Published 2023“…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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487
Mapping subnational HIV mortality in six Latin American countries with incomplete vital registration systems
Published 2021“…</p><h3>Results</h3><p dir="ltr">All countries displayed over a 40-fold difference in HIV mortality between municipalities with the highest and lowest age-standardized HIV mortality rate in the last year of study for men, and over a 20-fold difference for women. Despite decreases in national HIV mortality in all countries—apart from Ecuador—across the period of study, we found broad variation in relative changes in HIV mortality at the municipality level and increasing relative inequality over time in all countries. …”
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488
Gut microbiome and Parkinson's disease: Perspective on pathogenesis and treatment
Published 2023“…</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Advanced Research<br>License: <a href="http://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank">http://creativecommons.org/licenses/by-nc-nd/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jare.2022.10.013" target="_blank">https://dx.doi.org/10.1016/j.jare.2022.10.013</a></p>…”
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489
Luspatercept's use in a patient with transfusion‐dependent beta‐thalassemia and intrathoracic extramedullary hematopoiesis (EMH)
Published 2024“…<h3>Key Clinical Message</h3><p dir="ltr">This case report and literature review examine the use of a relatively novel agent in a transfusion‐dependent beta‐thalassemia patient with extramedullary hematopoiesis (EMH). …”
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490
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
Published 2025“…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …”
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491
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
Published 2021“…Taken together, these data confirmed fascin’s role in promoting TNBC progression, and identified a novel opportunity for therapeutic interventions via targeting those FSCN1-related transcripts.</p><p dir="ltr"><br></p><h2>Other Information</h2><p dir="ltr">Published in: Pharmaceuticals<br>License: <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank">https://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.3390/ph14121228" target="_blank">https://dx.doi.org/10.3390/ph14121228</a></p>…”
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492
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
Published 2019“…However, potential side effects related to ChNP toxicity remain the major limitation hampering their wide application. …”
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493
Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
Published 2025“…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”
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494
Non-diabetic ketoacidosis secondary to primary hyperthyroidism
Published 2022“…This was associated with decreased appetite and weight loss.</p><h3>Diagnosis</h3><p dir="ltr">Laboratory findings were significant for high anion gap metabolic acidosis, positive ketones in the urine, and high serum B-hydroxybutyrate. …”
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495
Oxidative stress cytotoxicity induced by platinum-doped magnesia nanoparticles in cancer cells
Published 2021“…Pt/MgO nanoparticles also induced production of reactive oxygen species, decreased cellular glutathione level, and increased lipid peroxidation. …”
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496
Cytokine-chemokine network driven metastasis in esophageal cancer; promising avenue for targeted therapy
Published 2021“…</p><p> </p></div><h2>Other Information</h2> <p> Published in: Molecular Cancer<br> License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1186/s12943-020-01294-3" target="_blank">https://dx.doi.org/10.1186/s12943-020-01294-3</a></p>…”
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497
Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system
Published 2023“…The results demonstrate that the proposed indices effectively capture the contribution of RES to MG reliability and offer valuable insights for decision-making related to RES installation. Also, by integrating BESS, the contribution of RESs to outage hours and lost energy is effectively decreased from 89.41% and 87.41% to 32.69% and 28.94% respectively. …”
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498
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
Published 2024“…</p><h2>Other Information</h2><p dir="ltr">Published in: Journal of Clinical Densitometry<br>License: <a href="http://creativecommons.org/licenses/by/4.0/" target="_blank">http://creativecommons.org/licenses/by/4.0/</a><br>See article on publisher's website: <a href="https://dx.doi.org/10.1016/j.jocd.2024.101547" target="_blank">https://dx.doi.org/10.1016/j.jocd.2024.101547</a></p>…”
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499
Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
Published 2020“…</p><h3>Results</h3><p dir="ltr">In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. This was driven by increased hexokinase-2 linked glucose metabolism and related increased MG formation. …”
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500
Ratings of Perceived Exertion Misclassify Intensities for Sedentary Older Adults During Graded Cycling Test: Effect of Supramaximal High-Intensity Interval Training
Published 2018“…For both groups, RPE decreases with SCE at 10 min following graded test correlated significantly to V˙O<sub>2</sub> (r = 0.61, p < 0.01). …”