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281
Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021
Published 2024“…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …”
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282
Global, regional, and national burden of stroke and its risk factors, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2021“…During the same period, age-standardised rates of stroke incidence decreased by 17·0% (15·0–18·0), mortality decreased by 36·0% (31·0–42·0), prevalence decreased by 6·0% (5·0–7·0), and DALYs decreased by 36·0% (31·0–42·0). …”
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283
Wound healing potential of quercetin-3-O-rhamnoside and myricetin-3-O-rhamnoside isolated from Pistacia lentiscus distilled leaves in rats model
Published 2022“…Moreover, the cutaneous wound tissues treated with PDL 20, MM, and QM exhibited significantly higher hydroxyproline content than the negative control group, which means a high collagen biosynthesis in wound tissues. …”
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284
Global, regional, and national burden of hepatitis B, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019
Published 2022“…HBV-related death rates also decreased, but HBV-related death counts increased as a result of population growth, ageing, and <a href="https://www.sciencedirect.com/topics/medicine-and-dentistry/cohort-effect" target="_blank">cohort effects</a>. …”
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285
Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults
Published 2024“…FindingsFrom 1990 to 2022, the combined prevalence of underweight and obesity in adults decreased in 11 countries (6%) for women and 17 (9%) for men with a posterior probability of at least 0·80 that the observed changes were true decreases. …”
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286
Two-stage optimisation for malachite green removal using activated date pits
Published 2022“…The best fit for the experimental data for both treated and natural date stone was the Langmuir–Freundlich isotherm. …”
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287
Successful minimally invasive management of nonvascular grade IV blunt renal trauma with complete transection in a 7-year-old girl
Published 2022“…They can be treated with a minimally invasive combination of internal and external drainage. …”
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288
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
Published 2020“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
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289
Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies
Published 2021“…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …”
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290
Effectiveness of Intravenous Iron Therapy in the Management of Severe Iron Deficiency Anemia: A Retrospective Study
Published 2025“…The aim of this study is to retrospectively evaluate outpatients with iron deficiency anemia who refused blood transfusion and were treated with intravenous iron supplementation. This study is a retrospective study based on medical records. …”
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291
Increased footwear comfort is associated with improved running economy – a systematic review and meta‐analysis
Published 2021“…Running economy during constant submaximal running is likely improved in recreational runners wearing more comfortable compared to less comfortable footwear. …”
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292
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”
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293
12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase
Published 2013“…In vivo studies were performed using Ins<sup>2Akita</sup> mice treated with or without the 12/15-LOX inhibitor baicalein. …”
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294
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”
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295
Thermodynamic analysis of solar-driven integrated system for efficient brine management and hydrogen production
Published 2025“…Rejected brine from the RO process is treated using reverse electrodialysis (RED) and the photo-chloralkali (PCA) process to produce valuable chemicals, including hydrogen, which is converted into electricity using a proton exchange membrane (PEM) fuel cell. …”
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296
Use of Carbide Derived Carbon in Water Treatment and Thermal Fluids Applications
Published 2021“…Water scarcity is a global issue due to the increasing demand and consumption of natural water resources, which are under stress from; a growing human population, decreasing ground water tables and precipitation, and increasing agriculture, industrialization and urbanization. …”
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297
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”
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298
Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders
Published 2023“…More importantly, the proteome of treated cells displayed ~75% of the downregulated products as SP1 targets. …”
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299
Preterm birth in low-middle income Countries
Published 2024“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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300
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …”