A slow but steady nanoLuc: R162A mutation results in a decreased, but stable, nanoLuc activity by Wesam S. Ahmed (10170053)

“…Here, we combined molecular dynamics (MD) simulation and mutational analysis to show that the R162A mutation results in a decreased but stable <u>bioluminescence </u>activity of NLuc in living cells and in vitro. …”

Novel paclitaxel formulations solubilized by parenteral nutrition nanoemulsions for application against glioma cell lines by Najlah, Mohammad

“…The Polydispersity Indexes (PDIs) of all the nanoemulsion formulations (Clinoleic and Intralipid) were less than 0.2 irrespective of paclitaxel concentration indicating that all nanoemulsion formulations used were homogeneously sized. …”
Get full text
Get full text
Get full text

The role of NF-κB and AhR transcription factors in lead-induced lung toxicity in human lung cancer A549 cells by Ibraheem M. Attafi (14151735)

Effect of UV Ageing on the fatigue life of bulk polyethylene by Hamza Lamnii (18806002)

“…The results show an important decrease of the fatigue limit with increasing absorbed UV irradiation dose.…”

Impact of Work-Life Balance on Female Employee Motivation by Haleema Raja (22196926)

“…The study has revealed a link between work-life balance and employee motivation, suggesting that businesses that prioritize work-life balance policies will likely experience better levels of employee engagement, Productivity, well-being, retention, and decreased levels of stress. …”

Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan, Sirin

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
Get full text
Get full text
Get full text

Sanguinarine Induces Apoptosis Pathway in Multiple Myeloma Cell Lines via Inhibition of the JaK2/STAT3 Signaling by Sabah Akhtar (5809925)

“…In this study, we aimed to investigate the potential anti-proliferative and pro-apoptotic activities of SNG in a panel of MM cell lines (U266, IM9, MM1S, and RPMI-8226). SNG treatment of MM cells resulted in a dose-dependent decrease in cell viability through mitochondrial membrane potential loss and activation of caspase 3, 9, and cleavage of PARP. …”

The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading by Hozhabr Mozafari (18891892)

“…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …”

Impact of Life-coaching on Students' Wellbeing and Engagement Levels in a Preparatory School in Qatar by Abderrahmane Dedeche (20773958)

“…Both groups showed a decrease in satisfaction with life as well as most of the personality traits of the period of the school year. …”

The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe by Ammari, Lora

“…This thesis explores the relationship between living alone, loneliness, and quality of life (QoL) in elderly Europeans. This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
Get full text

Influence of temperature on tire-pavement noise in hot climates: Qatar case by Okan Sirin (14603304)

“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”

Life cycle assessment of binary recycled ceramic tile and recycled brick waste-based geopolymers by Namra Mir (17017734)

“…<p dir="ltr">This paper consists of a life cycle assessment (LCA) analysis on an experimental study to produce recycled brick waste (RBW) and recycled ceramic tile (RCT) based geopolymers. …”

Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane by Vasavi, Boggarapu

“…The results indicated that tensile and flexural strength decreased by 35.16 % and 29.3 % respectively, from S1 to S10. …”
Get full text
Get full text
Get full text

Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (DALYs), and healthy life expectancy (HALE) for 371 diseases and injuries in 204 co... by Alize J, Ferrari

“…FindingsGlobal DALYs increased from 2·63 billion (95% UI 2·44–2·85) in 2010 to 2·88 billion (2·64–3·15) in 2021 for all causes combined. Much of this increase in the number of DALYs was due to population growth and ageing, as indicated by a decrease in global age-standardised all-cause DALY rates of 14·2% (95% UI 10·7–17·3) between 2010 and 2019. …”
Get full text
Get full text
Get full text

The Anti-Tumor Agent Sodium Selenate Decreases Methylated PP2A, Increases GSK3βY216 Phosphorylation, Including Tau Disease Epitopes and Reduces Neuronal Excitability in SHSY-5Y Neu... by Wesal Habbab (17346961)

“…In this study we recorded maximum increase in total PP2A at 3 µM sodium selenate in a neuron cell line. In conjunction with these data, whole-cell electrophysiological studies revealed that this concentration had maximum effect on membrane potentials, conductance and currents. …”

3D Concrete Printing Sustainability: A Comparative Life Cycle Assessment of Four Construction Method Scenarios by Malek Mohammad (17150977)

“…Moreover, the use of an alternative concrete mixture in 3DCP showed a further decrease in the GWP, AP, EP, and FFD impact. Ultimately, the findings in this paper support the advantages of 3DCP technology and recommend the investigation of the development of (i) sustainable printable concrete materials and (ii) novel reinforcement techniques that are suitable for 3DCP rather than adopting conventional reinforcement techniques.…”

Life cycle assessment of compressed air, vanadium redox flow battery, and molten salt systems for renewable energy storage by Manal AlShafi (14778373)

“…This paper considers three energy storage techniques that can be suitable for hot arid climates namely; compressed air energy storage, vanadium redox flow battery, and molten salt thermal storage and performs a comprehensive life cycle assessment analysis to comparatively evaluate the environmental impacts per kWh of energy. …”

Assessment of treatment burden and its impact on quality of life in dialysis-dependent and pre-dialysis chronic kidney disease patients by Asmaa Al-mansouri (16931739)

“…<h3>Background</h3><p dir="ltr">The management of chronic kidney disease (CKD) and its complications places a significant burden on patients, resulting in impairment of their health-related quality of life (HR-QOL). Little is known about treatment-related burden in pre-dialysis and hemodialysis (HD) CKD patients.ObjectiveThis study aimed to investigate the magnitude of treatment-related burden and its impact on HR-QOL among patients with CKD.…”

Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2... by Michael, Brauer

“…From 2000 to 2021, there was an observable shift in global health challenges, marked by a decline in the number of all-age DALYs broadly attributable to behavioural risks (decrease of 20·7% [13·9–27·7]) and environmental and occupational risks (decrease of 22·0% [15·5–28·8]), coupled with a 49·4% (42·3–56·9) increase in DALYs attributable to metabolic risks, all reflecting ageing populations and changing lifestyles on a global scale. …”
Get full text
Get full text
Get full text

Health in times of uncertainty in the eastern Mediterranean region, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013 by Mokdad, Ali H

“…However, diarrhoeal diseases were the leading cause of death in Somalia (186·7 deaths per 100 000 people) in 2013, which decreased by 26·9% since 1990. The leading cause of disability-adjusted life-years (DALYs) was ischaemic heart disease for males and lower respiratory infection for females. …”
Get full text
Get full text
Get full text