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341
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
منشور في 2019"…Objective: In this study, we evaluated the effect of Suberoylanilide Hydroxamic Acid (SAHA), a panhistone deacetylase inhibitor, and Decitabine (DAC), a DNA methyltransferase inhibitor, either alone or in combination, on Caco-2 human colon cancer cell line in vitro. Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …"
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article -
342
NMR Study of the Interaction of Trinitrobenzene with High-Spin Tetraarylporphinato-Iron(II1) Halides
منشور في 1981"…The averaged TNB shifts and line-widths are indicative of 1:1 complexes whose stability is decreased by more electron-withdrawing axial halides or phenyl substituents, consistent with the porphyrin acting as a π donor in the adduct. …"
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article -
343
The effects of a change in the point system on immigration
منشور في 2016"…In parallel, points for a subjective assessment of “adaptability” were decreased. In line with the initial objective, we find more French-speaking immigrants with bachelor’s degrees, and no worsening in labor market outcomes after the reform. …"
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article -
344
Predicting stability of classes in an object-oriented system
منشور في 2010"…However, in almost all cases, these models were not efficient when used to predict the quality characteristics (stability or other) of new unseen software as their prediction accuracy decreases significantly. In this paper, we present a heuristic approach that relies on the adaptation and recombination of already built predictive models to new unseen software.The predictive models are all rule-based models and the approach is tested on the stability of classes in an object-oriented software system. …"
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article -
345
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346
Can bitcoin’s volatility be tamed?
منشور في 2018"…Bitcoin is a software for operating a peer-to-peer payment network with its own hard money, without having to rely on a trusted third party. As the use of this network has grown, the value of the token underpinning it has increased sharply, with its total outstanding supply currently exceeding $100 billion in value. …"
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article -
347
3D FEM Model on the Parameters’ Influence of EPB-TBM on Settlements of Single and Twin Metro Tunnels During Construction
منشور في 2022"…<p>The present research exposes the investigation on three-dimensional modeling of the single and twin metro tunnels for the case of the Tehran metro line. At first, simulation implemented on the comparison of the ground movements in the single and twin tunnels. …"
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348
Efficiency of Azithromycin-Loaded Lipid Polymer Hybrid Nano-vehicle as a Repurposing formulation in Colon Cancer Management
منشور في 2025"…It displayed a safe profile on HT29 cell line, with the coated formulation having the lowest IC50= 24.17 μM at 24 hours that even decreases at longer time intervals, which confirms its potential for colorectal cancer management.…"
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masterThesis -
349
Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment
منشور في 2020"…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …"
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masterThesis -
350
An empirical approach to understanding users' fake news identification on social media
منشور في 2021"…Design/methodology/approach This study employs a quantitative approach and proposes a behavioral model that explores the factors influencing users' identification of fake news on social media. It relies on data collected from a sample of 211 social media users which is tested using SEM. …"
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article -
351
miRNA-dependent regulation of STIM1 expression in breast cancer
منشور في 2019"…Consistently, overexpression of Ago2 results in decreased STIM1 protein levels in MDA-MB-231 cells. …"
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352
Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System
منشور في 2017"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
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article -
353
Investigating the Quality Combined Effect of Root Cause Analysis (RCA) in Quality Management in Manufacturing Firms
منشور في 2024"…This improvement led to decreased warranty claims, cost reductions, and enhanced product longevity, ultimately reinforcing the company's commitment to delivering high-quality products that exceed the customer's expectations. …"
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354
Power System Transient Stability Assessment Based on Machine Learning Algorithms and Grid Topology
منشور في 2023"…Features of transmission line maintenance were used to increase accuracy of estimation. …"
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article -
355
Detecting attacks in a cluster based QOS-OLSR protocol. (c2014)
منشور في 2014احصل على النص الكامل
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masterThesis -
356
Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas
منشور في 2020"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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357
Dynamic Analysis of Flexible Mechanisms with Clearance
منشور في 2016احصل على النص الكامل
doctoralThesis -
358
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
منشور في 2014"…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …"
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article -
359
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
منشور في 2011"…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …"
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article -
360
The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR)
منشور في 2023"…Therefore, we investigated the molecular mechanisms accompanied with the epigenetic regulation of NY-ESO-1 in 5-Aza-CdR-treated NCI–H1975 cell line. We showed significant induction of the NY-ESO-1 protein (**p < 0.0097) using Cellular ELISA. …"