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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. Decreased whole body exposure to MG-derived AGEs may be linked to increased weight specific physical activity of HSA-mUCP1 mice. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…From this and previous transcriptomic studies, signaling involved in enhanced removal of MG-modified protein is likely increased HSPB1-directed HUWE1 ubiquitination through eIF2α-mediated, ATF5-induced increased expression of HSPB1. Decreased whole body exposure to MG-derived AGEs may be linked to increased weight specific physical activity of HSA-mUCP1 mice. …”
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Influence of shelf-life duration on mechanical, thermal and shape recovery motion derivatives of shape memory polyurethane
Published 2024“…The present research, therefore explores the effect of shelf life on mechanical, thermal and shape recovery performance of polyurethane (PU) based shape memory polymer (SMP). …”
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Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…MG activated the intrinsic pathway of apoptosis, with decrease of mitochondrial and spliceosomal proteins. …”
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Effect of UV Ageing on the fatigue life of bulk polyethylene
Published 2018“…The results show an important decrease of the fatigue limit with increasing absorbed UV irradiation dose.…”
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Integration of Wind Catchers in Modern Residential Buildings in the UAE as a Means of Providing Thermal Comfort
Published 2014“…This research is an evaluation of the effectiveness of wind catchers as means of providing thermal comfort for modern residential buildings in the hot arid climates in the UAE. …”
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Work-life balance, perceived stress, & locus of control
Published 2014“…According to the result of this study, work life balance is positively affected by an increased level of control as well as a decreased level of perceived stress. …”
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The trans-10, cis-12 isomer of conjugated linoleic acid decreases adiponectin assembly by PPARγ-dependent and PPARγ-independent mechanisms
Published 2008“…The adipocyte-derived secretory protein adiponectin functions as an insulin-sensitizing agent. …”
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Sustainable Concrete Mix Design: Experimental Study of Life-Size Columns
Published 2025“…This study focused on assessing life-size isolated footings by replacing 10% of the cement, sand, and gravel with wood ash, fine glass, and recycled concrete aggregates, respectively. …”
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Effects of vitamin E derivatives on the proliferation of KG-1 leukemic cells in vitro
Published 2017“…XTT cell viability assay, which detects the presence of metabolically active cells, was used to assess cell proliferation. A decrease in proliferation of KG-1 cells was observed upon treatment with both forms of vitamin E derivatives; however, β-T3 was more potent than γ-T3 in promoting cell death with lower IC50 values. …”
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The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe
Published 2023“…This thesis explores the relationship between living alone, loneliness, and quality of life (QoL) in elderly Europeans. This research indicates a positive correlation between living alone and loneliness, with a greater effect on males, and identifies loneliness as an independent factor decreasing QoL. …”
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
Published 2021“…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …”
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Exploring students’ understanding of the second derivative within the context of a differential equations course
Published 2025“…The teaching of this course emphasizes a qualitative approach and therefore a solid understanding of the first and second derivatives is critical to determine the increase/decrease of solutions as well as their rate of increase/decrease. …”
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Environmental Footprint and Economics of a Full-Scale 3D-Printed House
Published 2021“…The economics of the selected structural systems were investigated through life cycle costing analysis (LCCA), that included mainly the construction costs and energy savings. …”
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Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma
Published 2008“…Expression of the platelet-derived growth factor receptor (PDGFR) correlates with metastatic medulloblastoma and PDGF treatment of medulloblastoma cells activates the pro-survival and pro-migratory pathways downstream of the receptor, for instance, increases extra-cellular regulated kinase (Erk1/2), Protein kinase B (Akt) and phosphatidylinositide 3-kinase (PI3K) activity and decreases phosphatase and tensin homolog (PTEN) expression and activity. …”
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Two-Surgeon Technique for Hepatic Parenchymal Transection of the Noncirrhotic Liver Using Saline-Linked Cautery and Ultrasonic Dissection
Published 2005“…To date, no single instrument has been designed that addresses both of these tasks. Saline-linked cautery is now widely used in liver surgery and is reported to decrease blood loss during liver transection, but data on its exact benefits are lacking. …”
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XPS and material properties of raw and oxidized carbide-derived carbon and their application in antifreeze thermal fluids/nanofluids
Published 2022“…<p>In this study, the stability, thermal conductivity and viscosity of carbide-derived carbon antifreeze thermal fluids were explored. …”
