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401
A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV
Published 2010“…Fabry disease is an X-linked lysosomal storage disorder that leads to abnormal accumulation of glycosphingolipids due to a deficiency of alpha-galactosidase A (AGAL). …”
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402
Self-Reported Sleep and Exercise Patterns in Patients with Schizophrenia: a Cross-Sectional Comparative Study
Published 2019“…Patients with schizophrenia have shown abnormal sleep patterns and decreased physical activity that were linked to their psychopathology and physical health. …”
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403
Exploring the influence of salesperson lone wolf tendencies on customer value co-creation: a social exchange perspective
Published 2025“…Although the potential link between salesperson personality traits and customer reactions in B2B sales has been suggested, it is unclear how the impact of salesperson’s LWTs on customer value co-creation is. …”
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404
Serum 25-hydroxyvitamin D concentrations are inversely associated with body adiposity measurements but the association with bone mass is non-linear in postmenopausal women
Published 2021“…<p dir="ltr">Vitamin D deficiency has been linked to increased adiposity and decreased bone density. …”
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405
Heart Rate Variability Analysis Reveals a Non-monotonic Relationship between Humanin Concentration and Cardiac Autonomic Regulation
Published 2022“…Humanin (HN), a mitochondrial-derived peptide, plays an important role in lowering OS. …”
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406
Performance analysis of a small-scale Orthopter-type Vertical Axis Wind Turbine
Published 2018“…Increasing solidity was achieved by either decreasing the blade aspect ratio or increasing the number of blades, both resulting in a higher peak power coefficient (Cp,max) of the VAWT. …”
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407
Capacity allocation for voice over IP networks using maximum waiting time models
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408
Cost-benefit analysis of antimicrobial stewardship program in a cancer setting in Qatar
Published 2024“…The total economic benefit of the ASP maturity was calculated as the sum of the cost savings and the cost avoidance associated with the service minus the operational cost.3 Cost savings were the reduction in therapy cost linked to decreased antimicrobial consumption and resource utilization. …”
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409
Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models
Published 2025“…ACSS2 inhibition significantly reduced the expression of pro-inflammatory cytokines such as Interleukin 8 (IL-8), IL-1β, and TNF-α, and attenuated activation of NF-κB and MAPK signaling pathways, as evidenced by decreased phosphorylation of p65 and ERK/MEK. These findings highlight a pro-inflammatory role for ACSS2 in IBD and identify it as a potential therapeutic target, warranting further validation in advanced models, including patient-derived organoids and in vivo systems.…”
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410
α-ketoglutarate (αKG) acts as a protective factor against chronic stress and has antidepressant properties by modulating BDNF levels in the brain
Published 2022“…In the hippocampus, aKG increases BDNF levels possibly through the PGC1a-BDNF pathway. In the NAc, aKG decreases BDNF levels possibly through the FNDC5-BDNF pathway.…”
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411
Waterpipe Tobacco Smoke Nicotine Mediates Resilience to Chronic Stress by Activating BDNF Signaling
Published 2020“…The involvement of brain-derived neurotrophic factor signaling in the nicotine-mediated effects was assessed with the tropomyosin receptor kinase B (TRKB) inhibitor, ANA-12. …”
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412
The Gut Microbiome and Colorectal Cancer: An Integrative Review of the Underlying Mechanisms
Published 2025“…While the incidence and mortality of CRC have decreased overall due to better screening, rates in adults under 50 have risen. …”
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413
Predictive Power of Random Forests in Analyzing Risk Management in Islamic Banking
Published 2024“…Concerns related to terrorism financing and cybersecurity risks have also decreased due to the better enforcement of anti-money laundering regulations and investments in cybersecurity infrastructure and education. …”
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414
A positive change in energy balance modulates TrkB expression in the hypothalamus and nodose ganglia of rats
Published 2009“…Brain-derived neurotrophic factor (BDNF) and its TrkB receptor play critical roles in the synaptic activity and plasticity of mature neurons and enhance adult neurogenesis. …”
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415
Direct assembly process
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416
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Based on its importance for cancer cells, we aim to investigate the molecular mechanisms that link HSP90 inhibition in colon cancer cells with oxidative stress and mitochondrial stress—related regulators.…”
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417
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…<div><p>Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. …”
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Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…These positive outcomes are mediated through the induction of the expression of a growth factor, brain derived neurotrophic factor (BDNF), in the hippocampus. …”
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masterThesis