Age‐associated cholesterol reduction triggers brain insulin resistance by facilitating ligand‐independent receptor activation and pathway desensitization حسب Adrián Martín‐Segura (18615133)

"…In recent studies, we reported that the mild and gradual loss of cholesterol in the synaptic fraction of hippocampal neurons during aging leads to a decrease in synaptic plasticity evoked by glutamate receptor activation and also by receptor tyrosine kinase (RTK) signaling. …"

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021 حسب Stein Emil, Vollset

"…MethodsUsing forecasts of major drivers of health such as the Socio-demographic Index (SDI; a composite measure of lag-distributed income per capita, mean years of education, and total fertility under 25 years of age) and the full set of risk factor exposures captured by GBD, we provide cause-specific forecasts of mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) by age and sex from 2022 to 2050 for 204 countries and territories, 21 GBD regions, seven super-regions, and the world. …"
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Double versus triple arthrodesis for adult-acquired flatfoot deformity due to stage III posterior tibial tendon insufficiency: a prospective comparative study of two cohorts حسب Amr A. Fadle (14150298)

"…The mean Hibbs angle decreased from 153.07 to 142.32° (MD = 10.54°, p < 0.001). …"

Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes حسب Dina Abushanab (10696501)

"…<h3>Aims</h3><p dir="ltr">Insufficient risk factor control can lead to a loss of millions of productivity-adjusted life years (PALYs). We aimed to assess the productivity burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) and examine the potential advantages of enhancing the control of modifiable CVD risk factors in Qatar. …"

Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar حسب Ayman Al-Dahshan (8962568)

"…</p><h3>Results</h3><p dir="ltr">A total of 327 pregnant women (mean age of 29.5 years ± 4.0) completed and returned the questionnaire (response rate: 87.5%). …"

Dynamic Change in Insulin Resistance Induced by Free Fatty Acids Is Unchanged Though Insulin Sensitivity Improves Following Endurance Exercise in PCOS حسب Myint Myint Aye (6404327)

"…Skewed data were log transformed and expressed as mean ± SEM.</p><h3>Results</h3><p dir="ltr">Before exercise, women with PCOS had a higher HOMA-IR and lower VO2 max than controls. …"

Infliximab versus ciclosporin in steroid resistant acute severe ulcerative colitis: a model-based cost-utility analysis of data from CONSTRUCT pragmatic trial حسب Mohammed Fasihul Alam (6832217)

"…Beyond 2-year trial follow-up, Markov model predicted a decrease in colectomy rate, but it remained slightly higher for ciclosporin. …"

Excess pCO2 and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor, Izumi

"…CO2 is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO2 to 464 μatm, similar to that observed. …"
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The Impact of COVID-19 on the HIV Cascade of Care in Botswana – An Interrupted Time Series حسب Alice Sehurutshi (21842696)

"…<p dir="ltr">Globally, Botswana has one of the highest burdens of HIV. This study estimated the impact of the COVID-19 pandemic on the HIV cascade of care in Sub-Saharan Africa. …"

Portfolio Selection Problem Using CVaR Risk Measures Equipped with DEA, PSO, and ICA Algorithms حسب Abdelouahed Hamdi (14158899)

"…It was found that when solving the Mean-CVaR model with evolutionary algorithms, the risk decreased. …"

Epidemiology of injuries from fire, heat and hot substances: global, regional and national morbidity and mortality estimates from the Global Burden of Disease 2017 study حسب Spencer L James (8673927)

"…First, we produced results on incidence, prevalence, years lived with disability, deaths, years of life lost and disability-adjusted life years from 1990 to 2017 for 195 countries and territories. …"

The global burden of cancer attributable to risk factors, 2010–19: a systematic analysis for the Global Burden of Disease Study 2019 حسب Christopher J L Murray (18278781)

"…Estimated cancer deaths and disability-adjusted life-years (DALYs) in 2019 and change in these measures between 2010 and 2019 are presented.…"

Performance comparison of different flow arrangements of 4-fluid internally-cooled liquid desiccant dehumidifiers حسب Ali Pakari (14158902)

"…The approximate difference between the best and poorest performing flow arrangements in terms of the decrease in supply air humidity ratio and enthalpy is 4.3% and 10.5%, respectively. …"

Experimental investigation of double-pipe heat exchangers in air conditioning applications حسب Saud Ghani (7205633)

"…Double-pipe heat exchangers are considered one of the practical solutions in today’s HVAC industry. …"

Simulation of the size-composition distribution of atmospheric nanoparticles over Europe حسب David Patoulias (4722960)

"…The ground level concentrations of particles with a diameter larger than 100 nm (N100) were reproduced with a daily normalized mean error of 40 % and a daily normalized mean bias of −20 %. …"

Land surface temperature responses to land use dynamics in urban areas of Doha, Qatar حسب Shikha, Patel

"…The LST data derived from remote sensing sources demonstrates an upward trend for summer and a contrasting trend for winter. Specifically, the mean summer LST increases by 7.64 °C (0.34 °C annually), and the mean winter LST decreases by 4.87 °C (0.22 °C annually). …"
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Modeling the risk-based decisions of the microgrid in day-ahead energy and reserve markets considering stochastic dispatching of electrical and thermal energy storages حسب Salah Bahramara (21347576)

"…Also, the risk-based behavior of the MGO showed that increasing the robust parameter decreases the reserve provided for the market and the net power trading with the market. …"

Water Footprint Assessment and Virtual Water Trade in the Globally Most Water-Stressed Country, Qatar حسب Nayla Higazy (17679453)

"…<p dir="ltr">Qatar is one of the most water stressed countries globally, despite Qatar’s aridity and its lack of freshwater resources, per capita water consumption became one of the highest in the world due to population growth, agricultural expansion, rapid urbanization and industrialization and it is expected to increase in the coming decades. …"

Mental health, burnout and resilience in community pharmacists during the COVID-19 pandemic: A cross-sectional study حسب Zeana, Samir AlKudsi

"…Participants had shown moderate resilience (mean score: 27.64 (SD = 8.31)) and their mean score fear of COVID19 was 15.67 (SD = 6.54). …"
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Excess pCO₂ and carbonate system geochemistry in surface seawater of the exclusive economic zone of Qatar (Arabian Gulf) حسب Connor Izumi (17337868)

"…CO₂ is lost from the Gulf due to gas exchange, decreasing DIC, and reducing pCO₂ to 464 μatm, similar to that observed. …"