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721
Hepato‐splanchnic fluxes during exercise in patients with cirrhosis—a pilot study
منشور في 2024"…Among the 14 amino acids measured, glutamate was released in the liver, while the uptake of free fatty acids decreased. During exercise at relatively low workloads, arterial lactate and ammonia levels were comparable to those seen in healthy subjects at higher workloads, while euglycemia was maintained due to sufficient hepatic glucose production. …"
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722
COVID-19 biomarkers for severity mapped to polycystic ovary syndrome
منشور في 2020"…However, it is observed that in metabolic conditions such as polycystic ovary syndrome expressed proteins differ compared to control women [2] and PCOS patients have increased platelet aggregation and decreased plasma fibrinolytic activity, resulting in a prothrombotic propensity [3, 4], with elevated coagulation markers [5]. …"
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723
Assessing the risk of angiotensin receptor blockers on major cardiovascular events: a systematic review and meta-analysis of randomized controlled trials
منشور في 2020"…Data extraction and quality assessment were also performed independently. The relative risk (RR) of all-cause mortality, myocardial infarction, and stroke were pooled using the IVhet model. …"
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724
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
منشور في 2019"…Compared to shoes only, mainly EVA tended to improve RE and comfort at submaximal running speeds. Specific CFO-related running mechanical adjustments included a reduced braking impulse occurring in the first 25% of contact time with EVA, whereas wearing TPU increased propulsive loading rate.…"
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725
3D Tissue-Engineered Vascular Drug Screening Platforms: Promise and Considerations
منشور في 2022"…<p dir="ltr">Despite the efforts devoted to drug discovery and development, the number of new drug approvals have been decreasing. Specifically, cardiovascular developments have been showing amongst the lowest levels of approvals. …"
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726
Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation
منشور في 2025"…Notable COX-2 inhibitory activities (IC<sub>50</sub> = 0.065–0.24 μM) were observed relative to celecoxib (IC<sub>50</sub> = 0.049 μM). …"
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727
Adaptation of a Mice Doppler Echocardiography Platform to Measure Cardiac Flow Velocities for Embryonic Chicken and Adult Zebrafish
منشور في 2019"…Theoretically, as the size of the imaged sample decreases, the frequency of the ultrasound transducer needed to image the sample increases. …"
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728
Coats disease in Saudi Arabia
منشور في 2012"…The reason for presentation was decreased vision in 11 cases (55 %), strabismus in 4 (20 %), leukocoria in 2 (10 %), and others in 3 (15 %) . …"
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article -
729
Comparison of Burr-Hole Craniostomy versus Twist-Drill Craniostomy Operations for Patients with Chronic Subdural Hematoma: A Systematic Review and Network Meta-Analysis
منشور في 2023"…<h3>Background</h3><p dir="ltr">Chronic subdural hematoma (CSDH) represents one of the most common neurologic disorders in the elderly. …"
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730
Fetoplacental transmission and placental response to SARS-CoV-2: Evidence from the literature
منشور في 2022"…The results indicated that SARS-CoV-2 induces placenta inflammation, and placenta susceptibility to SARS-CoV-2 decreases across the pregnancy window. Thus, SARS-CoV-2 infection in early pregnancy may adversely affect the developing fetus.…"
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731
From metabolic dysregulation to neurodegenerative pathology: the role of hyperglycemia, oxidative stress, and blood-brain barrier breakdown in T2D-driven Alzheimer’s disease
منشور في 2025"…Current vascular insults include the breakdown of the blood-brain barrier (BBB) and decreased brain perfusion, along with other contributory factors to conditions conducive to neurotoxicity. …"
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732
Does Ultrasound Really Good Enough to Evaluate the Pneumothorax in the Emergency Department
منشور في 2023"…The average age of the patients was 76.5%, with the youngest patient being 18 years old and the oldest one being 90 years old. Of the patients, 45.38% (n = 101) were men. …"
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733
Effectiveness of Positron Emission Tomography for Predicting Chemotherapy Response in Colorectal Cancer Liver Metastases
منشور في 2010"…We hypothesized that PET uptake levels were artificially decreased after chemotherapy. That is, lesions that appeared to be nonmalignant were actually viable malignant lesions.…"
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article -
734
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735
Activation of the unfolded protein response in high glucose treated endothelial cells is mediated by methylglyoxal
منشور في 2019"…We assessed if increased MG glycation induced proteotoxic stress, identifying related metabolic drivers and protein targets. Human aortal endothelial cells (HAECs) were incubated in high glucose concentration (20 mM versus 5 mM control) in vitro for 3–6 days. …"
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736
Urinary Metabolomic Markers of Protein Glycation, Oxidation, and Nitration in Early-Stage Decline in Metabolic, Vascular, and Renal Health
منشور في 2019"…<p>Glycation, oxidation, nitration, and crosslinking of proteins are implicated in the pathogenic mechanisms of type 2 diabetes, cardiovascular disease, and chronic kidney disease. Related modified amino acids formed by proteolysis are excreted in urine. …"
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737
Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy‐combustion supercritical CO<sub>2</sub> intercooled and reheated cycles under design and off‐d...
منشور في 2022"…The analyses were conducted at relatively low turbine inlet temperatures (TIT: 550–750°C) with compressor inlet temperature (CIT) varied from 33°C (wet‐cooling) to 50°C (dry‐cooling). …"
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738
Small molecule inhibition of stat3 enhances survival in mice with intracerebral melanoma
منشور في 2008"…In addition, WP1066 decreased the level of c-Myc and survivin in melanoma cells in a dose- and time-dependent manner. …"
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conferenceObject -
739
An empirical correlation-based model to predict solid-fluid phase equilibria and phase separation of the ternary system CH<sub>4</sub>-CO<sub>2</sub>-H<sub>2</sub>S
منشور في 2021"…However, acid gases have to be removed before the natural gas produced from these fields could be used. One of the novel concepts in this field is the utilization of solid phase formation of carbon dioxide and/or hydrogen sulfide. …"
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740
Past and future climate effects on population structure and diversity of North Pacific surfgrasses
منشور في 2024"…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …"