Novel thiazolones for the simultaneous modulation of PPARγ, COX-2 and 15-LOX to address metabolic disease-associated portal inflammation حسب Mai S., El-Shoukrofy

"…As well, the expression levels of 20-HETE, Il-1β and TNF-α were decreased in LPS-challenged RAW264.7 macrophages upon treatment with compound 2a. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Whole-Genome Molecular Characterization and Typing of Staphylococcus aureus Isolated from Lebanon حسب El Hassan, Sarah

"…Most of the studied isolates carried the blaZ gene, 45% were MRSA, and 32% were MDR. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Assessing the Built Environment’s Reflectivity, Flexibility, Resourcefulness, and Rapidity Resilience Qualities against Climate Change Impacts from the Perspective of Different Sta... حسب Mohammed M. Al-Humaiqani (18325554)

"…<p dir="ltr">The frequency and severity of climate change are projected to increase, leading to more disasters, increased built environment system (BES) vulnerability, and decreased coping capacity. Achieving resilience objectives in the built environment is challenging and requires the collaboration of all relevant sectors and professionals. …"

Stability enhancement of Al₂O₃, ZnO, and TiO₂ binary nanofluids for heat transfer applications حسب Ans Ahmed Memon (21633692)

"…Experimental work was carried out under several trials to enhance the stability of nanofluids. …"

Application of Enhanced Self-Adaptive Virtual Inertia Control for Efficient Frequency Control of Renewable Energy-Based Microgrid System Integrated with Electric Vehicles حسب Sonalika Mishra (22393114)

"…The validation of the proposed controller is carried out with a system injected with stochastic disturbances, high and low levels of renewable energies, denial of service attacks on renewable energy, and disturbed operating conditions with varied internal parameters. …"

Stochastic Programming for Hub Energy Management Considering Uncertainty Using Two-Point Estimate Method and Optimization Algorithm حسب Ali S. Alghamdi (17541711)

"…Additionally, the results show that TPEM approach dependability consideration decreased hub energy’s profit by 8.995% as compared to deterministic planning.…"

Effect of surfactants on the convective heat transfer and pressure drop characteristics of ZnO/DIW nanofluids: An experimental study حسب Adnan Qamar (14421759)

"…VC and TC increased by increasing the NFs concentration and decreased by increasing the operating temperature. …"

XPS and material properties of raw and oxidized carbide-derived carbon and their application in antifreeze thermal fluids/nanofluids حسب Ismail W. Almanassra (14151321)

"…Viscosity measurements showed that the gum arabic CDC suspensions have a higher viscosity than the oxidized CDC; the viscosity was growing with CDC and gum arabic loadings and decreased with temperature. The thermal conductivity analysis was carried out using a lambda analyzer in a temperature range of 288–338 K with a CDC mass loading range of 0.05–0.3 mass%. …"

Turkronicles: diachronic resources for the fast evolving Turkish language حسب Togay Yazar (22828175)

"…Despite the substantial vocabulary changes, we demonstrate that it is possible to identify old Turkish words that have the same meanings with newly coined ones using word embeddings. …"

Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC حسب Abhilash Dutta Roy (22466830)

"…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. We also observed an increase in mangrove and seagrass areas, likely due to recent conservation and afforestation efforts. …"

Innovative strategies to reduce traffic related injuries and deaths in youth حسب Joanne Banfield (19794507)

"…Studies have shown young drivers are more likely to underestimate the probability of specific risks caused by traffic situations, as well as to overestimate their own driving skills making them more vulnerable to trauma. …"

Stemming cardiovascular diseases in Qatar حسب Nature Research (16552612)

"…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.</p><p>All of these factors are associated with reduced physical activity and increased consumption of high-fat foods. …"

Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice حسب Julie Decock (44558)

"…These findings provide novel insight into the suppressive action of MMP-8 on mammary tumorigenesis and metastasis, and indicate that the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.…"

Quantitative Compressibility Effects in Thermal Elastohydrodynamic Circular Contacts حسب Habchi, W.

"…The results reconfirm the well-known observations that minimum film thickness is very little affected by lubricant compressibility while central film thickness decreases linearly with the increase in volume compression of the lubricant. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows حسب Tohid Adibi (17871551)

"…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …"

The Pros and Cons of Use of Handheld Electronic Devices During Ward Rounds and the Impact of the COVID-19 Pandemic حسب Shireen Suliman (13554986)

"…The COVID-19 pandemic led to a decrease in the use of HEDs by both faculty [38(64%)] and PGTs [42(60%)].…"

Public motives and willingness to participate in first-in-human clinical trials in Saudi Arabia: A new era in the making حسب Almutairi, Adel F.

"…In contrary, for every one unit increase in concern scores, the odds of enrollment decreased among study participants by 0.98 [0.97–0.99], adj.P = 0.017. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Mutations in L-type amino acid transporter-2 support SLC7A8 as a novel gene involved in age-related hearing loss حسب Meritxell Espino Guarch (18810097)

"…Thus, a screening of a cohort of ARHL patients and controls was carried out revealing several variants inSLC7A8, whose role was further investigated by in vitro functional studies. …"

The thioredoxin homolog YbbN functions as a chaperone rather than as an oxidoreductase حسب Kthiri, Fatoum

"…Escherichia coli contains two thioredoxins, Trx1 and Trx2, and a thioredoxin-like protein, YbbN, which presents a strong homology in its N-terminal part with thioredoxins, and possesses a 20 kDa C-terminal part of unknown function. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Investigating the structural impacts of a novel missense variant identified with whole exome sequencing in an Egyptian patient with propionic acidemia حسب Ali Zaki Ibrahim (17092957)

"…Computational analyses revealed that the novel variant might have a pathogenic effect that attributed to decreased protein stability, and also has an effect on the biotin carboxylase c-terminal domain of the propionyl carboxylase enzyme. …"