The molecular mechanisms of apoptosis accompanied with the epigenetic regulation of the NY-ESO-1 antigen in non-small lung cancer cells treated with decitabine (5-aza-CdR) حسب Varghese P. Inchakalody (14557382)

"…<p dir="ltr">Dysregulated epigenetic modifications are common in lung cancer but have been reversed using demethylating agent like 5-Aza-CdR. 5-Aza-CdR induces/upregulates the NY-ESO-1 antigen in lung cancer. …"

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 حسب Natalia V, Bhattacharjee

"…Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and family planning and support. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019: a systematic analysis... حسب Marissa B Reitsma (8674341)

"…Countries have a clear and urgent opportunity to pass strong, evidence-based policies to accelerate reductions in the prevalence of smoking and reap massive health benefits for their citizens.…"

Measuring routine childhood vaccination coverage in 204 countries and territories, 1980–2019: a systematic analysis for the Global Burden of Disease Study 2020, Release 1 حسب Natalie C Galles (9715361)

"…<h3>Background</h3><p dir="ltr">Measuring routine childhood vaccination is crucial to inform global vaccine policies and programme implementation, and to track progress towards targets set by the Global Vaccine Action Plan (GVAP) and Immunization Agenda 2030. …"

Global, regional, and national burden of HIV/AIDS, 1990–2021, and forecasts to 2050, for 204 countries and territories: the Global Burden of Disease Study 2021 حسب Austin, Carter

"…HIV-related deaths decreased by 39·7% (33·7–44·5), from 1·19 million (1·07–1·37) in 2010 to 718 000 (669 000–785 000) in 2021. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Global, regional, and national mortality among young people aged 10–24 years, 1950–2019: a systematic analysis for the Global Burden of Disease Study 2019 حسب Joseph L Ward (9715619)

"…Furthermore, indirect effects of the COVID-19 pandemic are likely to jeopardise efforts to improve health outcomes including mortality in young people aged 10–24 years. …"

Worldwide trends in underweight and obesity from 1990 to 2022: a pooled analysis of 3663 population-representative studies with 222 million children, adolescents, and adults حسب Nowell H, Phelps

احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Finding novel targets for the treatment and reversal of type 2 diabetes mellitus and obesity حسب Imran Ramzan (15430807)

"…Individually, both valine (245 ± 33 to 105 ± 23 µmol/L; p < 0.0001), and leucine (130 ± 20 to 75 ± 13 µmol/L; p < 0.05), decreased significantly in response to the BCAA-restricted diet. …"

Characteristics of aerosols and planetary boundary layer dynamics during biomass burning season حسب Muhammad Zeeshaan Shahid (18131689)

"…These findings provide key insights into the complex interactions between meteorology, emissions, and haze formation in NEP region, and will provide policy makers to design effective mittigation strategies.…"

Driving against the clock: Investigating the impacts of time pressure on taxi and non-professional drivers’ safety and compliance حسب Qinaat Hussain (15294164)

"…<p>Drivers often encounter time pressure, which can lead to riskier driving habits, decreased safety margins, and a higher chance of accidents. …"

A Case Study in Qatar for Optimal Energy Management of an Autonomous Electric Vehicle Fast Charging Station with Multiple Renewable Energy and Storage Systems حسب Abdulla Al Wahedi (17115613)

"…This interest has focused mainly on reducing the reliance on fossil fuel-based means of transportation and decreasing the harmful emissions produced from this sector. …"

Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas حسب Abu Saleh Md Moin (6189512)

"…<h3>Context: </h3><p dir="ltr">Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. …"

Effect of Intravenous Mannitol on Intraocular Pressure Changes in Vitrectomized and Non-Vitrectomized Eyes: A Systematic Review and Meta-Analysis حسب HASHEM ABU SERHAN (19737499)

"…In vitrectomized eyes, notable decreases were observed: at 30 min, the Ratio of Means (ROM) was 0.81 (95% CI: 0.53; 1.24), indicating a 19% reduction; at 60 min, the ROM of 0.833 (95% CI: 0.77; 0.89) showed a 16.7% reduction; at 90 min, the ROM of 0.757 (95% CI: 0.755; 0.758) corresponded to a 24.3% reduction; at 2 h, the ROM of 0.726 (95% CI: 0.642; 0.820) reflected a 27.4% reduction; at 3 h, the ROM of 0.692 (95% CI: 0.600; 0.797) resulted in a 30.8% reduction; and at 4 h, the ROM of 0.700 (95% CI: 0.363; 1.350) indicated a 30% reduction. …"

Unpacking the asymmetric impact of exchange rate volatility on trade flows: A study of selected developed and developing Asian economies حسب Umar Nawaz Kayani (17131781)

"…However, the result suggests that decreased volatility stimulates Malaysia’s exports. …"

The Influence of Loneliness and Living Alone on the Quality of Life of the Elderly: Evidence from Europe حسب Ammari, Lora

"…Concluding with policy recommendations emphasizing continuous evaluation and collaboration, this thesis highlights the need for targeted strategies to understand and alleviate loneliness among Europe’s elderly while acknowledging cultural diversity and gender differences.…"
احصل على النص الكامل

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
احصل على النص الكامل

Optimization of Community Integrated Energy System for the State of Qatar Towards Sustainable Development حسب Abdelrahman Mahmoud Ahmed Moursi (22674269)

"…The findings provide a pathway for sustainable urban planning and energy system design, reinforcing the significance of integrated energy solutions in achieving national targets.…"

Pilot testing of a novel Multi Effect Distillation (MED) technology for seawater desalination حسب Shahzada Aly (17191465)

"…Both the pilot testing and the simulation results confirm the features of the novel design of the MED. By implementing this invention's design, the heat transfer area has been decreased and accordingly, the capital cost of the evaporator is reduced by 20%. …"

Analysis of the resilience of the Turkey tourism industry to exogenous shocks: new evidence from a NARDL model حسب Lanouar Charfeddine (10705000)

"…Interestingly, the results reveal that terrorist attacks decreases have a higher impact on tourism demand compared to the impact of terrorist attacks increases. …"

Increased footwear comfort is associated with improved running economy – a systematic review and meta‐analysis حسب K. Van Alsenoy (21259700)

"…Running economy during constant submaximal running is likely improved in recreational runners wearing more comfortable compared to less comfortable footwear. …"