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381
Inhibiting HSP90 changes the expression pattern of PINK1 and BNIP3 and induces oxidative stress in colon cancer cells
Published 2025“…Similarly, genetic knockdown of HSP90 in RKO cells produced comparable effects, including reduced cell survival and a decreased PINK1/BNIP3 ratio.</p><h3>Conclusion</h3><p dir="ltr">Targeting HSP90 in colon cancer cells disrupts their survival by decreasing PINK1 and increasing BNIP3, which activates oxidative and endoplasmic reticulum stress, ultimately triggering apoptosis.…”
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382
The effect of Hydrogen Peroxide treatments on dental enamel porosity and protein structure and its long-term implications on tooth hardness and optical properties
Published 2025“…Hardness analysis revealed significant decreases in microhardness in the bleached group compared to the control group (<i>p </i> < 0.05). …”
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383
Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy
Published 2019“…Cells were co-transfected with a C-terminal modified α-synuclein (SynT) and synphilin-1, and then treated with DHM (10 μM) and Sal B (50 μM) 16 hours after transfection; levels of α-synuclein aggregation decreased significantly (68% for DHM and 75% for Sal B). …”
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384
The impact of bank liquidity on the Lebanese banks’ risk taking behavior
Published 2018“…This conclusion might suggest that higher capital requirements under Basel III are likely to increase bank risk with the implementation of new liquidity ratio. …”
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385
Effectiveness and specificity of a classroom-based group intervention in children and adolescents exposed to war in Lebanon
Published 2008“…The rates of disorders peaked one month post-war and decreased over one year. There was no significant effect of the intervention on the rates of MDD, SAD or PTSD. …”
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386
Effect of structural remodeling (retraction and recoil) of the pipeline embolization device on aneurysm occlusion rate
Published 2014“…On average, it increases its diameter by 0.23 mm and decreases its length by 2.88 mm within 6 months of initial deployment. …”
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387
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …”
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388
CRISPR-Cas Controls Cryptic Prophages
Published 2022“…Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …”
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389
Preterm birth in low-middle income Countries
Published 2024“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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390
Synergistic Effect of Epigenetic Inhibitors Decitabine and Suberoylanilide Hydroxamic Acid on Colorectal Cancer In vitro
Published 2019“…Results: Our results showed that SAHA and DAC, separately, significantly decreased cell proliferation, induced apoptosis and cell cycle arrest of Caco-2 cell line. …”
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391
Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…Interestingly, we also found that inhibition of autophagy in exercising 10-week-old mice decreases BDNF protein levels in the hippocampus as compared to the control exercising group. …”
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392
Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells
Published 2011“…Pre-treatment with sunitinib for 1 h also resulted in detachment and decreased viability of D556, but not Daoy, cells and only after 48 h following treatment. …”
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393
RHOG activates RAC1 through CDC42 leading to tube formation in vascular endothelial cells
Published 2019“…While knocking down either RHO, GTPase did not affect p-AKT levels, and p-ERK decreased in response to the knocking down of RHOG, CDC42 or RAC1. …”
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394
Tolfenamic Acid Derivatives: A New Class of Transcriptional Modulators with Potential Therapeutic Applications for Alzheimer’s Disease and Related Disorders
Published 2023“…More importantly, the proteome of treated cells displayed ~75% of the downregulated products as SP1 targets. …”
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395
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
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396
Successful endoscopic management of gastrojejunal anastomotic strictures after Roux-en-Y gastric bypas
Published 2007“…Dilation to at least 15 mm is safe and decreases the need for further endoscopic dilation.…”
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397
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
Published 2023“…The limited requests for retribution are likely due to a sense of impunity and adaptation to cumulative trauma. …”
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398
Evaluation of transportation network reliability during unexpected events with multiple uncertainties
Published 2016“…These uncertainties are likely due to the effect of natural disasters on road networks. …”
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399
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…<h3>Context: </h3><p dir="ltr">Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. …”
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400
Fitness training and work productivity in Lebanon. (c2006)
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masterThesis