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321
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Gaussian accelerated molecular dynamics (GaMD) simulations of the predicted alpha-helical synthetic Mpro cleavage sequences revealed a dynamic nature of the cleavage sequences, which is critical for their efficient cleavage, and a relatively short end-to-end distances, which is required for high BRET. Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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322
Addressing Challenges of Distance Learning in the Pandemic with Edge Intelligence Enabled Multicast and Caching Solution
Published 2022“…Moreover, user preferences and network’s contextual information can differentiate between live and cached access patterns optimizing edge caching decisions. …”
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323
Trends and levels of the global, regional, and national burden of appendicitis between 1990 and 2021: findings from the Global Burden of Disease Study 2021
Published 2024“…Although mortality rates due to appendicitis decreased in all regions, there were large regional variations in the temporal trend in incidence. …”
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324
The impact of bank liquidity on the Lebanese banks’ risk taking behavior
Published 2018“…This conclusion might suggest that higher capital requirements under Basel III are likely to increase bank risk with the implementation of new liquidity ratio. …”
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325
Epidemiological and clinical characteristics of fall-related injuries: a retrospective study
Published 2020“…Males were predominant (89%), more likely to fall at workplace, fall from a greater height and have polytrauma than females. …”
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326
CRISPR-Cas Controls Cryptic Prophages
Published 2022“…Specifically, compared to the wild-type strain, reducing the amounts of specific interfering RNAs (crRNA) decreases growth by 40%, increases cell death by 700%, and prevents persister cell resuscitation. …”
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327
Preterm birth in low-middle income Countries
Published 2024“…Although the overall trend is decreasing, this is mainly in high-income countries (HIC). …”
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328
Do Older Adults with Multimorbidity Meet the Recommended Levels of Physical Activity? An Analysis of Scottish Health Survey
Published 2019“…Independent predictors of meeting the recommended levels of PA include male gender [odds ratio (OR) 2.00 (95% confidence interval (CI) 1.58–2.54)], living in the least deprived areas [OR 1.79 (95% CI 1.20–2.69)]; being a non-smoker [OR 2.22 (95% CI 1.48–3. 34)]. …”
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329
Biochar from food waste: a sustainable amendment to reduce water stress and improve the growth of chickpea plants
Published 2022“…<p>The application of biochar in agriculture is a developing means to improve soil water retention, fertility, and crop yield. …”
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330
A Qualitative Investigation of University Students’ Experience of the Beirut Port Explosion
Published 2023“…The limited requests for retribution are likely due to a sense of impunity and adaptation to cumulative trauma. …”
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331
Evaluation of transportation network reliability during unexpected events with multiple uncertainties
Published 2016“…These uncertainties are likely due to the effect of natural disasters on road networks. …”
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332
Characterization of Non-hormone Expressing Endocrine Cells in Fetal and Infant Human Pancreas
Published 2019“…<h3>Context: </h3><p dir="ltr">Previously, we identified chromograninA positive hormone-negative (CPHN) cells in high frequency in human fetal and neonatal pancreas, likely representing nascent endocrine precursor cells. …”
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333
Fitness training and work productivity in Lebanon. (c2006)
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334
StarD13 is a tumor suppressor in breast cancer that regulates cell motility and invasion
Published 2014“…In general, the more aggressive the tumor, the more rapidly it grows and the more likely it metastasizes. Members of the Rho subfamily of small GTP-binding proteins (GTPases) play a central role in breast cancer cell motility and metastasis. …”
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335
Conflict in Ukraine and the unsettling ripples: implications on food systems and development in North Africa
Published 2024“…Algeria) will likely be able to mitigate the adverse effects on their citizens. …”
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336
Hypertension in Childhood Nephrotic Syndrome
Published 2019“…Others are associated with chronic and more sustained HTN such as renal fibrosis, decreased GFR, and progression of chronic kidney disease. …”
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337
The Effect of EVA and TPU Custom Foot Orthoses on Running Economy, Running Mechanics, and Comfort
Published 2019“…Albeit not reaching statistical significance (P = 0.11, η<sup>2</sup> = 0.12), RE on average improved in EVA (+2.1±4.8% and +2.9±4.9%) and TPU (+0.9±5.9% and +0.9±5.3%) compared to CON at LS and HS, respectively. Braking force was decreased by 3.4±9.1% at LS and by 2.7±9.8% at HS for EVA compared to CON (P = 0.03, η<sup>2</sup> = 0.20). …”
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338
An Investigation into the factors influencing Arabic speaking students’ proficiency in the Arabic language in Dubai British School
Published 2022“…The primary findings of the study are that while all the students’ proficiency was negatively influenced by the factor of language variation of the Arabic language, such an influence was felt more by the students in the British schools. This is likely due to the difference in linguistic environment experienced by the students in the British schools, relative to those in the Arabic schools, and which this study significantly correlated with decreased proficiency. …”
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339
Hepatitis serology predicts tumor and liver-disease characteristics but not prognosis after resection of hepatocellular carcinoma
Published 2004“…Patients with hepatitis were more likely to have tumors smaller than 5 cm and bilateral HCC involvement. …”
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340
Numerical analysis of spatial distribution of carbon in methane dry reforming over supported nickel catalyst in a packed bed reactor
Published 2024“…As the temperature increased, the total carbon deposition decreased, although this reduction became negligible beyond 850 °C. …”
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