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141
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
منشور في 2018"…These effects are likely dependent on the inhibition of eIF4A activity since we observed similar results using PatA. …"
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142
Transcriptome Profile Identifies Actin as an Essential Regulator of Cardiac Myosin Binding Protein C3 Hypertrophic Cardiomyopathy in a Zebrafish Model
منشور في 2022"…These knockout zebrafish displayed significant morphological heart alterations related to a significant decrease in ventricular and atrial diameters at systolic and diastolic states at the larval stages. …"
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143
PD-L1 Expression in Human Breast Cancer Stem Cells Is Epigenetically Regulated through Posttranslational Histone Modifications
منشور في 2019"…In summary, EMT-associated overexpression of PD-L1 was partially independent of promoter CpG methylation and more likely to be dependent on posttranslational histone modifications. …"
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144
Efficient Integration of Direct Air Capture With HVAC System
منشور في 2025"…Experimental results with sorbents like SBA-15 functionalized with Tetraethylenepentamine (TEPA) show substantial increases in CO<sub>2</sub> adsorption capacity. …"
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145
Meta-Heuristic Algorithm-Tuned Neural Network for Breast Cancer Diagnosis Using Ultrasound Images
منشور في 2022"…Early diagnosis is the only way to increase the treatment options which then decreases the death rate and increases the chance of survival in patients. …"
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146
Evapotranspiration and water availability response to climate change in the Middle East and North Africa
منشور في 2021"…The analysis predicted a shortage of water availability (precipitation—AET), which is alarming for most MENA regions. Relative to the reference period (1981–2010), the decline in annual water availability would reach 26 (62) mm by 2100 under SSP2-4.5 (SSP5-8.5). …"
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147
Genetic Variation in CCL5 Signaling Genes and Triple Negative Breast Cancer: Susceptibility and Prognosis Implications
منشور في 2019"…In the TCGA TNBC/Basal-like cohort the <b><i>MAP3K21</i></b><b> </b><b>rs1294255-G</b> allele was associated with a decreased OVS. …"
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148
Investigation of Groundwater Depletion in the State of Qatar and Its Implication to Energy Water and Food Nexus
منشور في 2021"…Long-term temperature data indicates that the annual mean temperature increased significantly by 1.02 °C between 1987 and 2016, while total rainfall exhibited a slight decreasing trend. …"
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149
A genetically encoded BRET-based SARS-CoV-2 Mpro protease activity sensor
منشور في 2022"…Further, in vitro assays with the BRET-based Mpro sensors revealed a molecular crowding-mediated increase in the rate of M<sup>pro</sup> activity and a decrease in the inhibitory potential of GC376. The sensors developed here will find direct utility in studies related to drug discovery targeting the SARS-CoV-2 M<sup>pro</sup> and functional genomics application to determine the effect of sequence variation in M<sup>pro</sup>.…"
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150
Energy-Efficient Cell Association and Load Balancing for Low Battery Users in Heterogeneous Cellular Networks
منشور في 2025"…This paper proposes improved cell association schemes based on the battery levels of UE and Deep Q-learning (DQL) to achieve load balancing and to decrease the power consumption of Low Battery Users (LBUs). …"
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151
Leveraging sentiment analysis of Arabic Tweets for the 2022 FIFA World Cup insights, incorporating the gulf region
منشور في 2024"…These insights hold the potential to inform future decisions related to the hosting of major sporting events, providing a unique perspective on the evolving dynamics of sentiment within this demographic.…"
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152
Children safety risk factors in Khorasan Razavi province
منشور في 2015"…The paper includes a review of the literature and a description of new research carried out on correlates of injury severity and measures of their relative effects on fatal or high injury collisions. …"
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153
Detailed organic characterization of process water to evaluate reverse osmosis membrane fouling in industrial wastewater treatment
منشور في 2024"…After ACF treatment, the hydrophobic organics decreased to 0.65 mg/L, revealing that the ACF is removing >50 % of hydrophobic organics which are likely responsible for membrane fouling. …"
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154
Studying coral reef patterns in UAE waters using panel data analysis and multinomial logit and probit models
منشور في 2020"…Like coral reefs around the world, the reefs of the United Arab Emirates (UAE) are facing global climate change and associated threats. …"
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155
The impact of climatic conditions on the carcinogenic and non-carcinogenic risk of BTEX compounds: A systematic review and meta-analysis
منشور في 2024"…For different climatic conditions, the overall mean and 95 % confidence interval (CI) of the effect size related to the carcinogenic and non-carcinogenic risk of BTEX were calculated using a random effect model. 26 articles passed the inclusion/exclusion criteria and were included in this review. …"
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156
Wales’ tourists not a burden for local healthcare
منشور في 2016"…The team categorized these injuries according to how they happened: mechanical fall, sporting injury, work-related, alcohol-related, alleged assault, outdoor pursuits, and others (including animal bites and stubbing a toe). …"
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157
Stemming cardiovascular diseases in Qatar
منشور في 2015"…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.</p><p>All of these factors are associated with reduced physical activity and increased consumption of high-fat foods. …"
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158
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
منشور في 2015"…These findings provide novel insight into the suppressive action of MMP-8 on mammary tumorigenesis and metastasis, and indicate that the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.…"
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159
Factors Affecting Waterpipe Tobacco Smoking among University Students in Qatar
منشور في 2021"…Compared to non-users, waterpipe tobacco users were significantly more likely to believe that waterpipe tobacco is less addictive than cigarettes (<i>p</i> = 0.009) and significantly less likely to believe that waterpipe tobacco can lead to cardiovascular diseases (<i>p</i> = 0.003) or dental problems (<i>p</i> = 0.02). …"
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160
Healthcare Professionals' Attitudes Toward Patients With Mental Illness: A Cross-Sectional Study in Qatar
منشور في 2022"…Stigmatizing attitudes by HCP can have adverse consequences on people with mental illness from delays in seeking help to decreased quality of care provided. Assessing such attitudes is an essential step in understanding such stigma and, if needed, developing and testing appropriate and culturally adapted interventions to reduce it.…"