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381
Frugal innovation for sustainable rural development
Published 2023“…We developed a classification that identifies the increasing positive and decreasing negative parameters of SDGs to assess the extent to which frugal enterprises contribute to specific SDGs. …”
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382
Luspatercept's use in a patient with transfusion‐dependent beta‐thalassemia and intrathoracic extramedullary hematopoiesis (EMH)
Published 2024“…<h3>Key Clinical Message</h3><p dir="ltr">This case report and literature review examine the use of a relatively novel agent in a transfusion‐dependent beta‐thalassemia patient with extramedullary hematopoiesis (EMH). …”
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383
Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
Published 2023“…<p dir="ltr">Metabolic reprogramming is one of the hallmarks of tumorigenesis. Here, we show that nuclear myosin 1 (NM1) serves as a key regulator of cellular metabolism. …”
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384
Associations between Bone Mineral Density and WOMAC Scores in Healthy Individuals: Insights from the Qatar Biobank
Published 2024“…<u>The Western Ontario and McMaster Universities Osteoarthritis Index</u> (WOMAC) is used to assess the severity of symptoms related to pain, stiffness, and function in diseased hip and knee joints. …”
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385
Glycolytic overload-driven dysfunction of periodontal ligament fibroblasts in high glucose concentration, corrected by glyoxalase 1 inducer
Published 2020“…</p><h3>Results</h3><p dir="ltr">In high glucose concentration cultures, there was a ca. twofold increase in cellular MG, cellular protein MG-H1 content and decreased attachment of PDLFs to collagen-I. This was driven by increased hexokinase-2 linked glucose metabolism and related increased MG formation. …”
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386
Type 2 Diabetes Coagulopathy Proteins May Conflict With Biomarkers Reflective of COVID-19 Severity
Published 2021“…A hyperinsulinemic clamp was performed and normoglycemia induced in T2D [4.5 ± 0.07 mmol/L (81 ± 1.2 mg/dl)] for 1-h, following which blood glucose was decreased to ≤2.0 mmol/L (36 mg/dl). Proteomic analysis for the complement and coagulation cascades were measured using Slow Off-rate Modified Aptamer (SOMA)-scan.…”
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387
Development of new reliability metrics for microgrids: Integrating renewable energy sources and battery energy storage system
Published 2023“…The results demonstrate that the proposed indices effectively capture the contribution of RES to MG reliability and offer valuable insights for decision-making related to RES installation. Also, by integrating BESS, the contribution of RESs to outage hours and lost energy is effectively decreased from 89.41% and 87.41% to 32.69% and 28.94% respectively. …”
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388
A BRET-based Mpro biosensor containing a nanobody and tandem cleavage sites shows an increased cleavage rate
Published 2025“…Live cell assays revealed a cleavage sequence length-dependent resonance energy transfer, except for the 12× -syn cleavage site, and an increased rate of cleavage and a decreased pharmacological inhibitor efficacy for the Mpro biosensor containing 2× cleavage sequences. …”
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389
Epstein–Barr Virus Epidemiology, Serology, and Genetic Variability of LMP-1 Oncogene Among Healthy Population: An Update
Published 2018“…EBV is highly prevalent since it affects more than 90% of individuals worldwide and has been linked to several malignancies including PTLDs, which are one of the most common malignancies following transplantation. …”
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390
Assessment of High-resolution Local Emissions and Land-use in Air Quality Forecasting at an Urban, Coastal, Desert Environment
Published 2022“…The overall forecast error decreased from –51% to 8% for PM2.5 and from –88% to 20% for NOx while a significant improvement was observed in the diurnal profile of predicted ozone. …”
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391
Bacterial diseases of Asian sea bass (Lates calcarifer): A review for health management strategies and future aquaculture sustainability
Published 2024“…<p>The advent of aquaculture has been one of the most significant shifts in world food supply during the last century. …”
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392
Effect of AlN nanoparticle concentration in the electrolyte on corrosion resistance and mechanical properties of the electrodeposited composite coatings
Published 2024“…<p>The impact of corrosion is widespread, affecting structures, equipment, and infrastructure across various industries increasing the maintenance cost and thereby decreasing profit and efficiency. Nickel-based coatings are one of the most tempting options owing to their enhanced mechanical and corrosion-resistant properties. …”
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393
Understanding the Molecular Mechanisms of Dysglycemia in Patients with Fanconi-Bickel Syndrome
Published 2023“…Both of the exonic mutations had overexpression of dysfunctional GLUT2 (characterized by decreased glucose uptake activity in PBMCs and mitigated glucose release activity in HEK293T). …”
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394
Exponential Particle Swarm Optimization for Global Optimization
Published 2022“…Particle Swarm Optimization (PSO) is one of the most famous nature-inspired algorithms owing to its simplicity and ability to be used in a wide range of applications. …”
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395
Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar
Published 2021“…<div><p>Human parvovirus (B19V) is the causative agent of erythema infectiosum in children and is linked to a wide range of clinical manifestations. Studies related to B19V prevalence in the Middle East and North Africa (MENA) region and other parts of Asia are very scarce. …”
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396
The Trace Element Composition of Size Fractionated Suspended Particulate Matter Samples from the Qatari EEZ of the Arabian Gulf: The Role of Atmospheric Dust
Published 2019“…The excess concentrations, relative to average dust, for most elements (except Cd) decreased with distance from shore, which may be due to differences in biology, currents, proximity to the coast or interannual processes.…”
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397
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
Published 2024“…In aged mice, CR attenuated trabecular bone loss, suggesting that CR may revert some aspects of age-related bone dysfunction. Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …”
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398
Impaired Liver Size and Compromised Neurobehavioral Activity are Elicited by Chitosan Nanoparticles in the Zebrafish Embryo Model
Published 2019“…However, potential side effects related to ChNP toxicity remain the major limitation hampering their wide application. …”
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399
Klotho overexpression protects human cortical neurons from β-amyloid induced neuronal toxicity
Published 2025“…Our data reveal that upregulation of <i>KLOTHO</i> significantly reduced β-amyloid-induced neuronal degeneration and apoptosis, as evidenced by decreased cleaved caspase-3 expression and preservation of axonal integrity. …”
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400
Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021
Published 2024“…The reference forecast is our estimate of the most likely fertility future given the model, past fertility, forecasts of covariates, and historical relationships between covariates and fertility. …”
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