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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
منشور في 2023"…Proteomics analysis of skeletal muscle revealed a shift to increased heat shock proteins and mechanoprotection and repair in HSA-mUCP1 mice. Decreased MG-derived AGE protein content in skeletal muscle of aged HSA-mUCP1 mice is therefore likely produced by increased proteolysis of MG-modified proteins and increased proteostasis surveillance of the skeletal muscle proteome. …"
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Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex
منشور في 2022"…Additionally, we find that the N501Y mutant S1-RBD displays altered dynamics that likely aids in its enhanced interaction with ACE2. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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The Effect of Number of Corrugation on Crashworthiness of Aluminum Corrugated Tube under Lateral Loading
منشور في 2017"…The results show that tubes with corrugations have a higher mean crushing force which is directly proportional to the number of corrugations. …"
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Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
منشور في 2025"…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of -0.16 mmol/L and -0.48 mmol/L, respectively. …"
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Influence of temperature on tire-pavement noise in hot climates: Qatar case
منشور في 2021"…There is an apparent trend of decreasing temperature coefficient with increasing mean texture depth of dense graded asphalt pavements. …"
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The ortholog of human ssDNA-binding protein SSBP3 influences neurodevelopment and autism-like behaviors in <i>Drosophila melanogaster</i>
منشور في 2023"…<p dir="ltr">1p32.3 microdeletion/duplication is implicated in many neurodevelopmental disorders-like phenotypes such as developmental delay, intellectual disability, autism, macro/microcephaly, and dysmorphic features. …"
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Unraveling the impaired incretin effect in obesity and type 2 diabetes: Key role of hyperglycemia-induced unscheduled glycolysis and glycolytic overload
منشور في 2024"…<p>Glucagon-like peptide-1 (GLP-1) agonists and GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) co-agonists are major treatment options for subjects with obesity and patients with type 2 diabetes mellitus (T2DM). …"
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Exploring beyond numeric weight loss: The metabolic effects of semaglutide
منشور في 2025"…Furthermore, semaglutide was the only effective Glucagon Like Peptide-1 Receptor Agonist in reducing Low-Density Lipoprotein and total cholesterol levels, with mean differences of −0.16 mmol/L and −0.48 mmol/L, respectively. …"
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Rooftop Photovoltaic Systems Adoption Using a Sequential Mixed Methods Approach in Qatar
منشور في 2024"…</p><p dir="ltr">The economic viability of a PV system relies on the country’s policies, customer acceptance, and the state of the economy. …"
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Water Footprint Assessment and Virtual Water Trade in the Globally Most Water-Stressed Country, Qatar
منشور في 2023"…The virtual water exports gradually decreased over the years with the most notable decrease in 2018 following Qatar’s blockade. …"
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IoT‐based mock oxygenator for extracorporeal membrane oxygenation simulator
منشور في 2023"…The approach is intrinsically costly since it relies on disposable medical equipment (i.e., oxygenators, heat exchangers, and pumps) that must be replaced regularly due to the damage caused by the liquid used to simulate blood. …"
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Effective non-intrusive load monitoring of buildings based on a novel multi-descriptor fusion with dimensionality reduction
منشور في 2020"…The latter can not only reduce feature dimensionality, but it can also effectively decrease the intra-class distances and increase the extra-class distances of appliance features; and (iii) a powerful decision bagging tree classifier is implemented to accurately classify electrical devices using the reduced features. …"
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Automated detection of posterior urethral valves in voiding cystourethrography images: A novel AI-Based pipeline for enhanced diagnosis and classification
منشور في 2024"…Traditional diagnosis relies on subjective interpretation of imaging techniques. …"
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Predictors of prolonged hospitalization among geriatric trauma patients using the modified 5-Item Frailty index in a Middle Eastern trauma center: an 11-year retrospective study
منشور في 2025"…There was a significant decrease in the trend of geriatric trauma over the years. …"
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Aortic valve function post-replacement of severe aortic stenosis by transcatheter procedure versus surgery: a systematic review and metanalysis
منشور في 2021"…TAVR was associated with 37% (95% CI [0.51–0.78) mean RR reduction of post-procedural PPM, a decrease that was not affected by the surgical risk at inclusion, neither by the transcatheter heart valve system. …"
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Hyper-Hypo study: A Retrospective Observational Study of Neonatal Hypoglycemia Related to Maternal Hypertension
منشور في 2023"…However, a sub-group comparison of neonates (with initial blood glucose <2.6 mmol/L) showed methyldopa to be marginally associated with a 2 mmol/L decrease from the mean initial blood glucose, mean 1.6 ± 0.5 mmol/L, and methyldopa (1.4 ± 0.5 mmol/L; p= .045). …"
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Utilization of the internet for physical activity and diet information and its influence on pregnant women’s lifestyle habits in Qatar
منشور في 2023"…Also, participants who used the internet for diet information a great deal were more likely to decrease the amount of sugary and fatty foods they ate compared to women who used the internet somewhat or very little (61.4, 45.2, and 18.2%, p < 0.001; respectively) and (50.9, 30.4, and 18.2%, p = 0.001; respectively).…"