Potential mechanisms of human recombinant arginase I (Co)-PEG5000 [HuArgI (CO) - PRG5000] induced cytotoxicity in glioblastoma cells. (c2018) by El Jawhari, Yassmine

“…Cytotoxicity of [HuArgI (Co)-PEG5000] was tested on two GBM cell lines, namely A172 and U251. Both cell lines showed increased sensitivity at longer incubation periods of [HuArgI (Co)-PEG5000] treatment with IC50 values in the pM range, a result attributable to the arginine auxotrophy expressed in those two cell lines. …”
Get full text
Get full text
Get full text

Characterizing the Effect of Arginine Deprivation on Autophagic Response in Breast Cancer cells by Haidar, Fatemah

“…In this project, we first inspected ASS-1 expression in human breast cancer patients and found that it decreases progressively with tumorigenesis and metastasis. …”
Get full text
Get full text
Get full text

Machine Learning Models for Scheduling On-Demand Fog Placement and Optimizing Container Deployment by Farhat, Peter

“…Second, we propose a K-Means based clustering model embedded within a multi-objective optimization scheme for fog and container placement. …”
Get full text
Get full text
Get full text

Underrepresentation of racial and ethnic minorities in cascade testing for hereditary cancer syndromes by Muhammad Danyal Ahsan (14488278)

“…Cascade testing is critical as relatives found to carry a pathogenic gene variant have the opportunity to pursue targeted cancer risk reduction and early detection, decreasing cancer-associated morbidity and mortality. …”

Intravitreal adalimumab in active noninfectious uveitis by Hamam, Rola N.

“…Seven out of 12 eyes had improvement of ≥2 ETDRS lines. Three out of three eyes had resolution of anterior chamber cells. …”
Get full text
Get full text
Get full text
Get full text

Chemotherapy prior to Hepatic Resection for Colorectal Liver Metastases: Helpful until Harmful? by Abdalla, Eddie K.

“…Importantly, bevacizumab decreases the incidence and severity of sinusoidal injury with oxaliplatin therapy. …”
Get full text
Get full text
Get full text

Correlation of MPTP neurotoxicity in vivo with oxidation of MPTP by the brain and blood-brain barrier in vitro in five rat strains by Riachi, Naji J.

“…Decreased striatal dopamine levels in these latter rat strains were associated with increased dopamine turnover. …”
Get full text
Get full text
Get full text
Get full text

Why some firms export? An empirical analysis for manufacturing firms in the MENA region by Fakih, Ali

“…Also, they indicate that the propensity to export of these firms decreases with larger domestic market size. The empirical analysis reveals considerable variations in the effects of the determining factors when carrying out the estimation for individual countries.…”
Get full text
Get full text
Get full text

Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System by Bair, Scott

“…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…”
Get full text
Get full text
Get full text
Get full text

Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models by Mezher, Nawal

“…Using Caco-2 and HT-29 intestinal epithelial cell lines stimulated with Tumor Necrosis Factor-α (TNF-α) or Dextran Sodium Sulfate (DSS) as in vitro models of inflammation, we observed upregulation of ACSS2 protein expression. …”
Get full text
Get full text
Get full text

Hemodynamics of small aneurysm pairs at the internal carotid artery by Jou, Liang-Der

“…Cerebral aneurysms carry significant risks because rupture-related subarachnoid hemorrhage leads to serious and often fatal consequences. …”
Get full text
Get full text
Get full text
Get full text

Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling by Fostok, Sabreen

“…Background: The expression of connexin 43 (Cx43) is disrupted in breast cancer, and re-expression of this protein in human breast cancer cell lines leads to decreased proliferation and invasiveness, suggesting a tumor suppressive role. …”
Get full text
Get full text
Get full text
Get full text

Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters by Ali Yeganeh (16624998)

“…., intercept, slope and average residual between sample and reference lines) by integrating them with run rules in order to quickly detect various magnitudes of shifts in profile parameters. …”

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas by Tejedor, Alejandro

“…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…”
Get full text

Breast cancer cells and bone marrow mesenchymal stromal cells by Faour, Wissam H.

“…Co-cultures with either MG-63 cells or MSCs induced OPG and MMP-2 in both tumor cell lines. Interestingly, conditioned medium from co-cultures of MSCs and MDA-MB-231 cells significantly decreased the proliferation of activated T lymphocytes which was reversed by addition of anti-OPG antibodies to the co-cultures. …”
Get full text
Get full text
Get full text

Elastic Buckling Behavior of Functionally Graded Material Thin Skew Plates with Circular Openings by Alashkar, Adnan

“…Moreover, as the opening shifts from the plate’s edge closer to the center, the critical buckling load decreases by 26%. The critical buckling load is also dependent on the power index, as an increase in the power index from 0.2 to 5 reduced the buckling load by 1698 kN. …”
Get full text

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …”

Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation by Ghazi, Nicola G.

“…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …”
Get full text
Get full text
Get full text
Get full text

PSA-activated proaerolysin as a prostate specific cancer therapy by Abi-Habib, Ralph

“…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …”
Get full text
Get full text
Get full text

The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) by Khoury, Nathalie El

“…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …”
Get full text
Get full text