ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] حسب Abdel Khalek, Maya

"…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects حسب Majdi Mansouri (16869885)

"…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …"

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy حسب Taki, Fatima

"…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes حسب Maryam Aghadi (17128819)

"…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …"

STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration حسب Ayat S. Hammad (9592374)

"…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca²⁺ entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …"

EXPERIMENTAL STUDY OF HYBRID LIQUID DESICCANT BASED VAPOR COMPRESSION COOLING SYSTEM حسب Al-Farayedhi, A.

"…Results show that the ratio of the outlet-to-inlet absolute humidity reaches a steady state value of about 0.6 and the temperature of air decreased from 48 to 38o C in the dehumidifier of the hybrid system. …"
احصل على النص الكامل

An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im... حسب Khreibi, Rima Abou

"…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …"
احصل على النص الكامل

Developing a Framework for improving Business Continuity Management success (BCM) in UAE Construction Industry حسب ALFALASI, ALMUR ABDULLA

"…Study even identified that employee’s performance was decreased and new challenges come in workplace. For that various factors were responsible such that enforce new technology, insufficient labour training, inadequate early construction planning, high complexity in construction and inadequate early construction planning etc.…"
احصل على النص الكامل

Enhancing Thermal Comfort for the Revitalization of Pedestrian-Friendly Shopping Arcades in Dubai, UAE حسب RAJEEV, ANN MARIA

"…The most favorable cases are selected from each phase, and the final reduction in temperature and PMV values of the optimized case indicates a substantial decrease of 3.76 degrees Celsius in air temperature post-implementation of passive design strategies. …"
احصل على النص الكامل

Media, technology use, and attitudes: associations with physical and mental well‐being in youth with implications for evidence‐based practice حسب Zeeni, Nadine

"…Moreover, social media could be used as a platform for intervention and prevention programs to decrease BID, EDs, depression, and anxiety.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

The impact of green supply chain management practices on environmental performance during COVID-19 period: the case of discretionary companies in the G-20 countries حسب El Khoury, Rim

"…It highlights the impact of green initiatives to cope with major disruptions and decrease pollution and environmental disaster.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways حسب Shehaby, Wassim N.

"…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Occupational Violence at Lebanese Emergency Departments حسب Dimassi, Hani

"…Such measures will be necessary to protect the well-being and decrease the turnover of ED workers.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma حسب Shebaby, W.

"…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Behavior of axially loaded drilled shaft foundations with symmetric voids outside and inside the caging حسب Abishdid, Caesar

"…Drilled shaft foundations usually carry very high design loads, and often serve as a single load-carrying unit. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Particle size impact on pyrolysis of multi-biomass: a solid-state reaction modeling study حسب Sabah Mariyam (14150859)

"…Both activation energy and pre-exponential factor decreased from 18.78 to 5.57 kJ/mol and 1.16 E+10 to 1.48 E+08 with reducing particle sizes. …"

Nonlinear Multimode Vibration Attenuation Using Passive Circuits حسب Kadri, Khaled

احصل على النص الكامل

Effect of StarD13 on colorectal cancer proliferation, motility and invasion حسب Nasrallah, Anita

"…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro حسب Rizk, Sandra

"…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…"
احصل على النص الكامل
احصل على النص الكامل
احصل على النص الكامل

Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression حسب Rayanah Barnawi (8737584)

"…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1^KD) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …"