Modeling circadian clock–cell cycle interaction effects on cell population growth rates by El Khatib, N.

“…Particularly, we show that Cry 1, Cry 2 mutations decrease the growth rate of cells, Per 2 mutation enhances it and Bmal 1 knockout increases it for autonomous periods of the cell cycle less than 21 h and decreases it elsewhere. …”
Get full text
Get full text
Get full text
Get full text

Grid electricity demand reduction through applying passive and active strategies for a house in Baghdad, Iraq by Al-Badri, Nadia Rashid

“…By adopting 1Pearl, it provided 4.33% energy reduction while 2 Pearls can achieve about 4.37% decrease in energy. This means that roof insulation should take priority when considering the passive solutions for conserving energy. …”
Get full text

Daucus carota pentane-based fractions arrest the cell cycle and increase apoptosis in MDA-MB-231 breast cancer cells by Shebaby, Wassim N.

“…In this study we examined the anticancer effect of Daucus carota oil extract (DCOE) fractions on the human breast adenocarcinoma cell lines MDA-MB-231 and MCF-7 and clarified the mechanism of action. …”
Get full text
Get full text
Get full text

Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells by Al Sayyed, Fatima

“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
Get full text
Get full text
Get full text

Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon by Mokhbat, Jacques M.

“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
Get full text
Get full text
Get full text
Get full text

Sunitinib induces PTEN expression and inhibits PDGFR signaling and migration of medulloblastoma cells by Castellino, R.C.

“…However, sunitinib did not induce apoptosis in either cell line at any time point, indicating that the anti-migratory effects of sunitinib were not due to impeding cell survival. …”
Get full text
Get full text
Get full text
Get full text

In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation by Sleiman, Sama F.

“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
Get full text
Get full text
Get full text

Differential water quality in confined and free-flowing water bodies, Lebanon by Korfali, Samira Ibrahim

“…This emphasises the importance of assessing surface water quality as a projected means to increase water availability. This study involves two different water bodies, the freely flowing Nahr-Ibrahin River and the Qaraaoun Reservoir, an impoundment of the Litani River. …”
Get full text
Get full text
Get full text

Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States by Yahya, Fares

“…The quantification of mental states was performed by means of statistical analysis of indexes based on GTA, behavioral responses of time-on-task (TOT), and Brunel Mood Scale (BRMUS). …”
Get full text

Testing and Evaluation of a Smart Irrigation System towards Smart landscaping in UAE by ALSULAIMANI, FATMA

“…The outcomes of the use of SMS have shown a better results in water conservation and a decrease in water flow in the month of September by 21% and 26% in October. …”
Get full text

A framework for implementing Green Supply Chain Management: The Case of Petco Gulf by HASSAN, HUDA YOUSIF ALI AHMED

“…From this research, it was found that as Petco gulf is present in the U.A.E. it can take advantage of this and by applying the GSCM strategies against each of its components this will help the company by, increased overall gross profit with the decrease in cost since going green in its supply chain means reducing the overheads. …”
Get full text

Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses by Merilyn Lock (9440240)

“…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …”

A modified lipid composition in Fabry disease leads to an intracellular block of the detergent-resistant membrane-associated dipeptidyl peptidase IV by Rizk, Sandra

“…Possible consequences could be altered signalling at the cell surface triggered by DRM-associated proteins, with implications on gene regulation and subsequent protein expression.…”
Get full text
Get full text
Get full text

Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat by Dimassi, Hani I.

“…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …”
Get full text
Get full text

The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013) by Nasrallah, Anita I.

Get full text
Get full text

ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000] by Abdel Khalek, Maya

“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
Get full text
Get full text
Get full text

Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects by Majdi Mansouri (16869885)

“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”

Cytotoxicity of Arginine Deprivation to AML Cells is Mediated by Autophagy by Taki, Fatima

“…[HuArgI(Co)-PEG5000]-induced arginine deprivation led to significant and sustained activation of autophagy starting at 24 hours and lasting up to 120 hours following arginine deprivation in all cell lines. Inhibition of autophagy, using chloroquine, led to a significant decrease in cell cytotoxicity evident at 48 hours and up to 120 hours. …”
Get full text
Get full text
Get full text

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes by Shadi Nejat (19457212)

“…Similarly, KO 47 mice also showed a slower rate of glucose clearance in GTT that was consistent with decreased mRNA expression of the GLUT4 gene in WAT but not in the muscle. …”

Driving simulation sickness and the sense of presence: Correlation and contributing factors by Mustafa Almallah (17280568)

“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”