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261
Loss of FOXA2 induces ER stress and hepatic steatosis and alters developmental gene expression in human iPSC-derived hepatocytes
Published 2022“…Here, we used FOXA2−/−iPSC lines to understand the role of FOXA2 on the development and function of human hepatocytes. …”
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262
Autophagy Mediates the Effects of Physical Exercise on Learning and Memory through Activation of Hippocampal BDNF
Published 2020“…Interestingly, we also found that inhibition of autophagy in exercising 10-week-old mice decreases BDNF protein levels in the hippocampus as compared to the control exercising group. …”
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masterThesis -
263
Thermal challenges in lithium-ion battery technology: Investigating performance and thermal stability
Published 2025“…Results show a significant reduction in discharge capacity, decreasing from 38.12 mAh in the first cycle to 24.36 mAh after 350 cycles at 55 °C, corresponding to a 36.1 % capacity loss. …”
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264
Fanconi–Bickel Syndrome: A Review of the Mechanisms That Lead to Dysglycaemia
Published 2020“…SLC2A2 encodes for glucose transporter 2 (GLUT2) a low affinity facilitative transporter of glucose mainly expressed in tissues playing important roles in glucose homeostasis, such as renal tubular cells, enterocytes, pancreatic β-cells, hepatocytes and discrete regions of the brain. Dysfunctional mutations and decreased GLUT2 expression leads to dysglycaemia (fasting hypoglycemia, postprandial hyperglycemia, glucose intolerance, and rarely diabetes mellitus), hepatomegaly, galactose intolerance, rickets, and poor growth. …”
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265
Efficacy And Safety of Cannabidiol on Juvenile Diabetes Outcomes in Male Rats
Published 2023“…Thus, CBD has the potential to decrease HbA1C in diabetic patients (Diabetes Mellitus type 1) and improve their lives. …”
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masterThesis -
266
Electric vehicles charging management using deep reinforcement learning considering vehicle-to-grid operation and battery degradation
Published 2023“…<p>EVs are becoming more popular and widely used worldwide due to their environmentally friendliness as part of the world efforts to decrease the effects of climate change. Moreover, more users are buying EVs due to governmental incentives, development of charging technologies and cheaper maintenance costs. …”
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267
Teachers’ Job Satisfaction in Instructional Delivery Modalities, and the Role of School Leaders: a Study among Selected Private Schools in Abu Dhabi.
Published 2022“…This result is derived from the change in the outcomes of the satisfaction factors: job security, workload, in-class effort, work-life balance, remuneration, leadership support, students’ behaviour, and relationship with co-workers. …”
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268
Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes
Published 2025“…AimsInsufficient risk factor control can lead to a loss of millions of productivity-adjusted life years (PALYs). We aimed to assess the productivity burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) and examine the potential advantages of enhancing the control of modifiable CVD risk factors in Qatar. …”
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269
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca<sup>2+</sup> entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”
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270
Driving simulation sickness and the sense of presence: Correlation and contributing factors
Published 2021“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”
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271
An investigation into links between UAE STI Policy and the Federal Universities STEM Majors’ Enrolments, Graduates and Research Development: an evidence-based exploration of the im...
Published 2020“…In terms of United Arab Emirates University (UAEU), there has been a decrease in STEM programs enrolment, while STEM graduates in UAEU has stayed steady at 1/3 STEM majors compared to 2/3 non-STEM programs. …”
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272
Orofacial Clefts
Published 2021“…We found markers of focal adhesions to be heavily localized at the tail regions of patient-derived cells that could explain this behavior. …”
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masterThesis -
273
Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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274
Caloric restriction reduces trabecular bone loss during aging and improves bone marrow adipocyte endocrine function in male mice
Published 2024“…Cortical bone, however, was decreased in young mice on CR and remained reduced in aged mice, irrespective of dietary intervention. …”
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275
Expanding the donor pool
Published 2002“…These measures may be beneficial in terms of increasing the number of donors and decreasing the waiting time. However, deviation from the standard method of cadaver donor selection is not without possible negative impact on graft survival. …”
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276
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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277
Energy Efficient Refurbishment for Existing Office Building in UAE
Published 2011“…The other principles are to decrease the energy use and related operational expenses while to increase use of environment-friendly materials and renewable energy sources. …”
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278
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
Published 2014“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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279
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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280
DNA methylation signature in peripheral blood reveals distinct characteristics of human X chromosome numerical aberrations
Published 2015“…The X inactivation process appears to be less effective in Klinefelter syndrome as methylation on the X was decreased compared to normal female samples. In a large number of individuals, we verified several loci by pyrosequencing and observed only weak inter-loci correlations between the verified regions. …”
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