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141
Studies of Glyoxalase 1-Linked Multidrug Resistance Reveal Glycolysis-Derived Reactive Metabolite, Methylglyoxal, Is a Common Contributor in Cancer Chemotherapy Targeting the Splic...
Published 2021“…Spliceosomal gene expression correlated positively with Glo1 in human tumor cell lines and tumors. In clinical chemotherapy of breast cancer, increased expression of Glo1 was associated with decreased patient survival, with hazard ratio (HR) = 1.82 (logrank p < 0.001, n = 683) where upper quartile survival of patients was decreased by 64% with high Glo1 expression.…”
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142
Global time differences in road traffic injuries among children and adolescents between and 1990 and 2013: Regional and economical perspectives from global burden of diseases study
Published 2015“…<p dir="ltr">In 2010, road traffic injuries (RTIs) are the leading cause of deaths in those aged 1-19 years globally and half of those victims are vulnerable road users (VRUs), defined as pedestrians, bicyclists and motorcyclists. …”
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143
Detailed organic characterization of process water to evaluate reverse osmosis membrane fouling in industrial wastewater treatment
Published 2024“…After ACF treatment, the hydrophobic organics decreased to 0.65 mg/L, revealing that the ACF is removing >50 % of hydrophobic organics which are likely responsible for membrane fouling. …”
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144
Analyzing the Influence of Climate and Anthropogenic Development on Vegetation Cover in the Coastal Ecosystems of GCC
Published 2025“…Our results revealed significant changes in land cover, as seen by an increase in artificial built-up areas by 15.5% in two decades and a corresponding decrease in bareland and dense vegetation. We also observed an increase in mangrove and seagrass areas, likely due to recent conservation and afforestation efforts. …”
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145
Innovative strategies to reduce traffic related injuries and deaths in youth
Published 2015“…Studies have shown young drivers are more likely to underestimate the probability of specific risks caused by traffic situations, as well as to overestimate their own driving skills making them more vulnerable to trauma. …”
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146
Stemming cardiovascular diseases in Qatar
Published 2015“…Many of the heart attack and stroke patients had diabetes, hypertension, high cholesterol, and/or were smokers, whereas controls were much less likely to have these factors.</p><p>All of these factors are associated with reduced physical activity and increased consumption of high-fat foods. …”
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147
Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice
Published 2015“…These findings provide novel insight into the suppressive action of MMP-8 on mammary tumorigenesis and metastasis, and indicate that the loss of MMP-8 likely has pleiotropic effects on innate immunity and angiogenesis that are reflected in changes in the protease web.…”
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148
Identification of genetic determinants of breast cancer immune phenotypes by integrative genome-scale analysis
Published 2017“…The mutation and neoantigen load progressively decreased from ICR4 to ICR1 but could not fully explain immune phenotypic differences. …”
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149
Investigation of the Effect of Imatinib and Hydroxyurea Combination Therapy on Hematological Parameters and Gene Expression in Chronic Myeloid Leukemia (CML) Patients
Published 2022“…<h3>Background</h3><p dir="ltr">Chronic myeloid leukemia is defined as the neoplastic development of mostly myeloid cells in the bone marrow. …”
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150
BCL-2 Inhibitor Venetoclax Induces Autophagy-Associated Cell Death, Cell Cycle Arrest, and Apoptosis in Human Breast Cancer Cells
Published 2020“…</p><h3>Methods</h3><p dir="ltr">Breast cancer cell lines with different molecular subtypes (MDA-MB-231, MCF7, and SKBR-3) were treated with different concentrations of VCX for indicated time points. …”
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151
Factors Affecting Waterpipe Tobacco Smoking among University Students in Qatar
Published 2021“…Compared to non-users, waterpipe tobacco users were significantly more likely to believe that waterpipe tobacco is less addictive than cigarettes (<i>p</i> = 0.009) and significantly less likely to believe that waterpipe tobacco can lead to cardiovascular diseases (<i>p</i> = 0.003) or dental problems (<i>p</i> = 0.02). …”
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152
Breaking the barriers towards large-scale microalgae-based bio-hydrogen production
Published 2025“…A CSTR nutrient-recovery line on digested <i>Scenedesmus</i> recovered 68 % N and 72 % P via struvite, reducing synthetic fertilizer ∼35 %; flue-gas CO<sub>2</sub> (12 % v/v) lifted biomass 22 % and reduced carbon-supplement cost 86 %. …”
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153
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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154
Fractionation and phytochemical composition of an ethanolic extract of Ziziphus nummularia leaves: antioxidant and anticancerous properties in human triple negative breast cancer c...
Published 2024“…F6 decreased MDA-MB-231 viability more than crude ZNE or its other fractions. …”
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155
Crystallization properties of arsenic doped GST alloys
Published 2019“…Optical band gap (E<sub>opt</sub>) values of the as-deposited films show a clear increasing trend; 0.6 eV for GST to 0.76 eV for (GST)<sub>0.85</sub>As<sub>0.15</sub>. The decreases in E<sub>opt</sub> for the samples annealed at higher temperatures shows significant optical contrast between the as-deposited and annealed samples. …”
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156
A new perspective on cardiovascular drift during prolonged exercise
Published 2021“…<p dir="ltr">Prolonged exercise induces cardiovascular drift, which is characterized by decreasing mean arterial pressure (MAP), stroke volume and heart rate increase. …”
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157
Prediction of biogas production from chemically treated co-digested agricultural waste using artificial neural network
Published 2020“…An ANN model consists of three layers, 15 neutrons and 260 <i>epochs</i> accurately predict the CMP with 99.1% of data within ±10% deviation of the mean experimental value. The developed model can be used to forecast the CMP as a function of operating temperature, the substrate composition, and chemical dose, and can be used for scaling-up and cost analysis purposes.…”
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158
Fluid-Structure-Acoustic coupling analysis for external laminar and turbulent fluid flows
Published 2023“…The results indicate that the transmission loss is 27% more at the elastic plate’s highest position. By decreasing the length of the elastic plate by 50%, the mean transmission loss is reduced by 9%. …”
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159
A kinetic evaluation of nutrient and organic matter removal in greywater for green Walls: Assessing the performance of Mineral-Based, Organic, and Waste-Derived plant support media
Published 2024“…<p dir="ltr">Greywater recycling provides a means to address rising water demand with reduced environmental impact due to its abundance and lightly polluted nature. …”
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160
The impact of COVID‐19 pandemic lockdown on smoking habits and lifestyle: A cross‐sectional study
Published 2023“…Participants who smoke were more likely to adopt an unhealthy lifestyle during the pandemic. …”