Sulforaphane Delays Fibroblast Senescence by Curbing Cellular Glucose Uptake, Increased Glycolysis, and Oxidative Damage حسب Florence Hariton (18629764)

"…SFN delayed senescence by decreasing glucose metabolism on the approach to senescence, exhibiting a caloric restriction mimetic-like activity and thereby decreased oxidative damage to cell protein and DNA. …"

Treatment sequencing strategy for hepatic epithelioid haemangioendothelioma حسب Thomas, Ryan

"…However, 5-year survival for patients treated with chemotherapy at any point during their disease course was decreased compared with those who did not receive any chemotherapy (43.6% versus 82.9%, respectively; P = 0.02) and was predictive of a decreased overall survival on univariate analysis [HR 3.1 (CI 0.9–10.7), P = 0.02]. …"
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Transfusion of Plasma from Young Exercise mice ameliorates Aging-associated Cognitive Impairments on Learning and Memory through activation of Autophagy حسب Khoury, Reine

"…Activation of BDNF signaling in mice treated with CQ did not rescue learning and memory deficits. …"
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The anti-cancer activity of 2 himachalene-6-OL extracted from daucus carota SSP. carota. (c2014) حسب Najm, Paul I.

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Investigating the mechanism by which the platelet-derived growth factor receptor promotes metastasis in medulloblastoma حسب AbouAntoun, Thamara Jihad

"…PDGF-BB treatment of cells enhanced migration and proliferation after 24 hr; increased PDGFRβ, PI3K, Akt and Erk1/2 activity, decreased PTEN activation and transactivated EGFR. …"
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PGAP3 Associated with Hyperphosphatasia with Mental Retardation Plays a Novel Role in Brain Morphogenesis and Neuronal Wiring at Early Development حسب Sahar I. Da’as (9631717)

"…The zebrafish functional modeling of PGAP3 loss resulted in HPMRS4-like features, including structural brain abnormalities, dysmorphic cranial and facial features, hypotonia, and seizure-like behavior. …"

Quantitative Elastohydrodynamic Film-Forming for an Oil/ Refrigerant System حسب Bair, Scott

"…It seems that only central film thicknesses have been experimentally measured for oil/refrigerant systems leaving these calculations as the only means of assessing the minimum.…"
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Hemodynamic effect of Neuroform stent on intimal hyperplasia and thrombus formation in a carotid aneurysm حسب Jou, Liang-Der

"…An 8 mm cavernous carotid aneurysm with a wide neck was treated by a Neuroform stent first and by coils five weeks later. …"
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Investigating the Role of Acetyl-CoA Synthetase Short Chain Family Member 2 (ACSS2) in Inflammatory Bowel Disease: Expression in Clinical Samples and Insights from In Vitro Models حسب Mezher, Nawal

"…Using Caco-2 and HT-29 intestinal epithelial cell lines stimulated with Tumor Necrosis Factor-α (TNF-α) or Dextran Sodium Sulfate (DSS) as in vitro models of inflammation, we observed upregulation of ACSS2 protein expression. …"
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Connexin 43 Loss Triggers Cell Cycle Entry and Invasion in Non-Neoplastic Breast Epithelium: A Role for Noncanonical Wnt Signaling حسب Fostok, Sabreen

"…Background: The expression of connexin 43 (Cx43) is disrupted in breast cancer, and re-expression of this protein in human breast cancer cell lines leads to decreased proliferation and invasiveness, suggesting a tumor suppressive role. …"
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Run Rules-Based EWMA Charts for Efficient Monitoring of Profile Parameters حسب Ali Yeganeh (16624998)

"…., intercept, slope and average residual between sample and reference lines) by integrating them with run rules in order to quickly detect various magnitudes of shifts in profile parameters. …"

Channel Network Control on Seasonal Lake Area Dynamics in Arctic Deltas حسب Tejedor, Alejandro

"…This shrinkage signal, easily extracted from remote sensing observations, may offer the means to constrain estimates of lacustrine methane emissions and to develop process-based estimates of depth to permafrost on arctic deltas.…"
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Self-assembly of Pseudo-Dipolar Nanoparticles at Low Densities and Strong Coupling حسب Mariano E. Brito (18622741)

"…This system self-assembles in a rich variety of string-like configurations, depicting three clearly distinguishable regimes with decreasing temperature: fluid, composed by isolated colloids; string-fluid, a gas of short string-like clusters; and string-gel, a percolated network. …"

Genetic Deletion of DNAJB3 Using CRISPR-Cas9, Produced Discordant Phenotypes حسب Shadi Nejat (19457212)

"…Three DNAJB3 knockout (KO) lines were generated (KO 30, 44 and 47), using CRISPR-Cas9. …"

12/15-Lipoxygenase-Derived Lipid Metabolites Induce Retinal Endothelial Cell Barrier Dysfunction: Contribution of NADPH Oxidase حسب Amira Othman (380131)

"…In vivo studies were performed using Ins^2Akita mice treated with or without the 12/15-LOX inhibitor baicalein. …"

Metformin attenuates V-domain Ig suppressor of T-cell activation through the aryl hydrocarbon receptor pathway in Melanoma: In Vivo and In Vitro Studies حسب Fawaz E., Alanazi

"…Here, metformin significantly decreased VISTA and AHR levels in vitro and in vivo. …"
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Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice حسب Ann Van der Jeugd (18629695)

"…Chronic sodium selenate treatment efficiently reversed hippocampal-dependent learning and memory impairments, and behavior- and neuropsychiatric-like symptoms in old female 3xTg-AD mice. Selenium significantly decreased the number of aggregated tau-positive neurons and astrogliosis, without globally affecting amyloid plaques, in the hippocampus of 3xTg-AD mice. …"

Intravitreal bevacizumab (Avastin) treatment of retinal angiomatous proliferation حسب Ghazi, Nicola G.

"…Results: Twelve eyes (92.3%) had stable or improved BCVA, and 8 eyes (61.5%) had at least 2 lines of vision improvement. The average BCVA improved from 20/203 at baseline to 20/113 at 12 weeks (P = 0.001). …"
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PSA-activated proaerolysin as a prostate specific cancer therapy حسب Abi-Habib, Ralph

"…Activity toward proaerolysin was decreased 10-100 fold for each of the proteases tested except PSA, which showed a 4-fold increase in activity against the modified protein. …"
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The mechanism of action of kefir and its effect on the motility of breast and colorectal cancer cells. (c2013) حسب Khoury, Nathalie El

"…In this study, we aim to determine a possible mechanism of action of kefir and to study its effect on the motility of colorectal and breast cancer cell lines. Results from the reverse-transcription PCR experiment have shown that kefir decreases the expression of TGF-α and TGF-β1 in HT-29 cells in a dose dependent manner. …"
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