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221
STIM1 signals through NFAT1 independently of Orai1 and SOCE to regulate breast cancer cell migration
Published 2023“…In contrast, Orai1-KO cells, which have similar levels of SOCE inhibition as STIM1-KO, migrate slower than the parental cell line. This shows that the enhanced migration phenotype of STIM1-KO cells is not due to the loss of Ca<sup>2+</sup> entry through SOCE, rather it involves transcriptional remodeling as elucidated by RNA-seq analyses. …”
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222
Driving simulation sickness and the sense of presence: Correlation and contributing factors
Published 2021“…Importantly, designing buildings that replicate a real-world environment could increase SP and decrease SS. Moreover, designing high quality and resolution scenarios could also increase SP, thus decreasing the severity of SS symptoms. …”
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Direct assembly process
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224
Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021
Published 2024“…In the assessment of alternative future scenarios, the combined effects of the scenarios (Safer Environment, Improved Childhood Nutrition and Vaccination, and Improved Behavioural and Metabolic Risks scenarios) demonstrated an important decrease in the global burden of DALYs in 2050 of 15·4% (13·5–17·5) compared with the reference scenario, with decreases across super-regions ranging from 10·4% (9·7–11·3) in the high-income super-region to 23·9% (20·7–27·3) in north Africa and the Middle East. …”
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Performance analysis of a small-scale Orthopter-type Vertical Axis Wind Turbine
Published 2018“…Increasing solidity was achieved by either decreasing the blade aspect ratio or increasing the number of blades, both resulting in a higher peak power coefficient (Cp,max) of the VAWT. …”
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227
Predictive Power of Random Forests in Analyzing Risk Management in Islamic Banking
Published 2024“…Findings reveal that larger banks provide more consistent survey responses, driven by their confidence and larger survey budgets. Moreover, a positive link is established between a country’s development, characterized by high GDPs and low inflation and interest rates, and the precision of Islamic banks’ survey responses. …”
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Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways
Published 2015“…Western blot revealed the activation of caspase-3, PARP cleavage, and a considerable increase in Bax and p53 levels, and a decrease in Bcl-2 level. Treatment of HT-29 cells with either fraction markedly decreased the levels of both phosphorylated Erk and Akt. …”
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230
Chemopreventive potential of the pentane-based fraction of wild carrot oil against chemically-induced squamous cell carcinoma
Published 2015“…The fractions were tested in vitro against several cancer cell lines and F1 was found to possess the highest activity. …”
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231
Effect of StarD13 on colorectal cancer proliferation, motility and invasion
Published 2014“…Colon cancer is a cancer of the epithelial cells lining the colon. It is mainly divided into different stages according to the invasiveness and metastatic ability of the tumor. …”
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232
Andrographolide pre-treatment enhances the anti-tumor activity of topotecan on acute myeloid leukemia cells in vitro
Published 2016“…Conclusion: Pretreating acute myeloid leukemia cell lines with non-cytotoxic doses of andrographolide promotes the anti-tumor effect of topotecan in vitro.…”
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233
Blockchain, climate damage, and death: Policy interventions to reduce the carbon emissions, mortality, and net-zero implications of non-fungible tokens and Bitcoin
Published 2022“…</p><p dir="ltr">Nonetheless, many popular types of blockchain have resisted the pressure to decrease their environmental impact, including Bitcoin, whose attributed 2021 annual emissions will produce emissions responsible for around 19,000 future deaths. …”
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234
Social Media Use and Body Checking Among Lebanese Adults
Published 2022“…That being said, interventions regulating social media content to limit the spread of unrealistic beauty standards and media literacy campaigns educating people may be helpful to decrease body checking behaviors thus decreasing the risk of body image dissatisfaction and disordered eating.…”
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235
eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
Published 2018“…Furthermore, we show that hippuristanol perturbs the activation of the STAT3 pathway and expression of STAT3-gene targets such as IL-6. The decreased activation of STAT3, which resulted from a decrease in STAT3 protein expression, was due to the inhibition of STAT3 translation as there were no changes in STAT3 mRNA levels. …”
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236
Comprehensive Transcriptome and Pathway Analyses Revealed Central Role for Fascin in Promoting Triple-Negative Breast Cancer Progression
Published 2021“…Herein, fascin ShRNA was used to generate stable fascin knockdown (FSCN1<sup>KD</sup>) in the MDA-MB-231 TNBC cell line and then were subjected to comprehensive mRNA and miRNA transcriptome analysis. …”
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237
Optical coherence tomography findings in autoimmune retinopathy
Published 2012“…Macular OCT showed reduced central macular and foveal thicknesses in 6 patients (mean thickness 143 ± 30 μm and 131 ± 29 μm respectively). …”
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Reducing terrorism with development ; the United Nations' new path. (c2009)
Published 2009Get full text
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