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221
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
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masterThesis -
222
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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223
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
Published 2013“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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Brain Connectivity Analysis Under Semantic Vigilance and Enhanced Mental States
Published 2019“…The quantification of mental states was performed by means of statistical analysis of indexes based on GTA, behavioral responses of time-on-task (TOT), and Brunel Mood Scale (BRMUS). …”
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226
Past and future climate effects on population structure and diversity of North Pacific surfgrasses
Published 2024“…Genetic diversity of <i>Phyllospadix torreyi </i>decreases from north to south, but in <i>Phyllospadix scouleri</i> the trend is variable. …”
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227
Testing and Evaluation of a Smart Irrigation System towards Smart landscaping in UAE
Published 2017“…The outcomes of the use of SMS have shown a better results in water conservation and a decrease in water flow in the month of September by 21% and 26% in October. …”
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228
A framework for implementing Green Supply Chain Management: The Case of Petco Gulf
Published 2021“…From this research, it was found that as Petco gulf is present in the U.A.E. it can take advantage of this and by applying the GSCM strategies against each of its components this will help the company by, increased overall gross profit with the decrease in cost since going green in its supply chain means reducing the overheads. …”
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229
Efficacy of Lebanese Cannabis Oil Extract in the Treatment of Folic Acid-Induced Renal Fibrosis in Rats
Published 2023“…In addition, a significant decrease in serum creatinine was observed in groups receiving cannabis extract at the doses of 5 and 10 mg/kg. …”
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masterThesis -
230
Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
Published 2023“…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …”
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231
Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat
Published 2006“…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …”
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232
Media, technology use, and attitudes: associations with physical and mental well‐being in youth with implications for evidence‐based practice
Published 2018“…Moreover, social media could be used as a platform for intervention and prevention programs to decrease BID, EDs, depression, and anxiety.…”
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233
The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013)
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234
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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235
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
Published 2021“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”
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236
Prophylactic and therapeutic antibiotic patterns of lebanese dentists for the management of dentoalveolar abscesses
Published 2016“…The data were analyzed with chi-square test and multivariate regression.Out of the 563 initial patients, 127 were selected for the study and received a local treatment. The patient's medical condition and age did not affect the decision to prescribe antibiotics 36.2% patients with pain and 11.8% patients with swelling were prescribed antibiotics. …”
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237
Effect of Acute and Chronic Moderate Red or White Wine Consumption on Fasted and Postprandial Lipemia in the Rat
Published 2006“…Animals in the chronic study received either red or white wine in drinking water for a period of 10 wk (3% v/v ethanol). …”
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Endocrine contribution to the sexual dysfunction in patients with advanced chronic kidney disease and the role of hyperprolactinemia
Published 2021“…Patients with hyperprolactinemia received treatment with cabergoline 0.5 mg once per week for 6 months and were re-evaluated. …”
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240
Adaptive Effects of Seeing Green Environment on Psychophysiological Parameters When Walking or Running
Published 2019“…However, the effects of seeing colors on self-selected behaviors have received little attention from physiologists and psychologists. …”