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261
Investigating The Efficacy of Ruxolitinib and CHIR-99021 in Targeting Pediatric Neuroblastoma Stem Cells
Published 2021“…In this study, we investigate the efficacy of two small molecules Ruxolitinib, a JAK/STAT inhibitor, and CHIR-99021, a GSK-3 inhibitor, in targeting pediatric neuroblastoma stem cells by testing them on human MYC-N amplified, IMR-32, and non-MYC-N amplified, SK-N-SH, cell lines. Treating neuroblastoma cells with Ruxolitinib and CHIR-99021 resulted in significant reduction in cellular proliferation, viability, apoptosis and tumorsphere formation capacity in both IMR-32 and SK-N-SH cell lines. …”
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masterThesis -
262
Potent anti-tumor promoting effects of Daucus carota oil extract in mice
Published 2008“…Inraperitoneal treatment inhibited tumor yield by 43%, and decreased the tumor volume by 85% at week 20. Gavage treatment failed to inhibit the promotion of tumors but decreased tumor volume by 20%. …”
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263
Screening for antiretroviral drug resistance among treatment-naive human immunodeficiency virus type 1-infected individuals in Lebanon
Published 2014“…Introduction: Antiretroviral therapy (ART) has been successful at decreasing the morbidity and mortality associated with human immunodeficiency virus type 1 (HIV-1) infection. …”
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264
In vitro ischemia suppresses hypoxic induction of hypoxia-inducible factor-1α by inhibition of synthesis and not enhanced degradation
Published 2013“…We validated the use of a reporter containing the oxygen-dependent degradation domain of HIF-1α fused to firefly luciferase (ODD-luc) to monitor quantitatively distinct biochemical events leading to hypoxic HIF-1α expression or stabilization in a human neuroblastoma cell line (SH-SY5Y). When OGD was imposed following a 2-hr hypoxic stabilization of ODD-luc, the levels of the reporter were reduced, consistent with prior models proposing that OGD enhances HIF prolylhydroxylase (PHD) activity. …”
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265
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266
The Potential Role of Daucus carota Aqueous and Methanolic Extracts on Inflammation and Gastric Ulcers in Rats
Published 2009“…Daucus carota (DC) is among commonly used plants in folk medicine in Lebanon and the region. The present investigation was undertaken to examine the effects of the aqueous and extracts of Daucus carota umbels against acute and chronic inflammation, gastric ulcer and antibacterial activity on rats. …”
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267
Differential water quality in confined and free-flowing water bodies, Lebanon
Published 2003“…This emphasises the importance of assessing surface water quality as a projected means to increase water availability. This study involves two different water bodies, the freely flowing Nahr-Ibrahin River and the Qaraaoun Reservoir, an impoundment of the Litani River. …”
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268
A framework for implementing Green Supply Chain Management: The Case of Petco Gulf
Published 2021“…From this research, it was found that as Petco gulf is present in the U.A.E. it can take advantage of this and by applying the GSCM strategies against each of its components this will help the company by, increased overall gross profit with the decrease in cost since going green in its supply chain means reducing the overheads. …”
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269
Thermodynamic analysis of gravity assisted solar-powered reverse osmosis unit for greenhouses situated in a depleted zone
Published 2021“…A thermodynamic analysis of the system is performed, and the results demonstrate that the use of an energy recovery turbine along with the geographical advantage of the region decreased the power requirement of the RO unit. …”
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270
Structural and physical properties of the dust particles in Qatar and their influence on the PV panel performance
Published 2016“…However, even when these characteristics have been addressed appropriately, there are other factors that adversely affect the performance of PV systems, namely the temperature-induced voltage decrease leading to a PV power loss and the dust accumulation (soiling). …”
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271
Combining Saliency with Prediction for Endoscopic Diagnosis
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doctoralThesis -
272
Cardiorespiratory Fitness and Performance Adaptations to High-Intensity Interval Training: Are There Differences Between Men and Women? A Systematic Review with Meta-Analyses
Published 2023“…Data were sub-grouped for men and women, baseline training level, mean age, intervention type, and intervention length. …”
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273
Carotid artery revascularization through a radiated field
Published 2003“…All patients had received previous radiation therapy within a mean interval of 10 years (range, 1-26 years), with average radiation dose of 62 Gy (range, 50-70 Gy). …”
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274
A Multidecadal Assessment of Haze Development and Fluctuations in Visibility for Arabian Peninsula
Published 2024“…Policymakers in the region can work on regional environmental policies to further improve the regional atmospheric visibility.…”
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275
Dietary Calcium Intake of 1200 mg/d May Have Negative Correlation on Percent Body Fat
Published 2006“…The high-calcium group (intake ≥1200 mg/d) had a significantly higher mean caloric intake (P ≤ .01) and significantly lower percent body fat (P ≤ .05) than the low-calcium group (intake <1200 mg/d). …”
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276
Media, technology use, and attitudes: associations with physical and mental well‐being in youth with implications for evidence‐based practice
Published 2018“…Moreover, social media could be used as a platform for intervention and prevention programs to decrease BID, EDs, depression, and anxiety.…”
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277
The effect of StarD13 on colorectal cancer proliferation and invasion. (c2013)
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masterThesis -
278
ROS-Mediated Autophagic Death in Glioblastoma Cells Upon Treatment by Human Recombinant Arginase I (Co)- PEG5000 [HuArgI (Co)-PEG5000]
Published 2021“…In this study, we examine the mechanism of HuArgI (Co)-PEG5000-induced cell death in both partially and completely auxotrophic GBM cell lines. Our results first showed a significant increase in HuArgI (Co)-PEG5000 treated cells for both U251 and A172 in autophagosome formation; suggesting activation of autophagy in response to arginine deprivation. …”
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masterThesis -
279
Deep Learning-Based Fault Diagnosis of Photovoltaic Systems: A Comprehensive Review and Enhancement Prospects
Published 2021“…These faults may affect the different system components such as PV modules, connection lines, converters/inverters, which can lead to a decrease in the efficiency, performance, and further system collapse. …”
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280
Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
Published 2023“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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